The Oakland Athletics had the most runs by an AL team in a game with >0 games played in 2018, with 21 runs against the Angels on September 20, 2018.

Interpreted as:

team most runs in a regular-season game 2018 al

	TEAM	R	G	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Athletics	21	1	9/20/2018	OAK	vs	LAA	W 21-3	44	22	4	0	3	20	7	0	7	0	0	51	35	7	0	0	0	2	.500	.569	.795	1.364
2	Red Sox	19	1	9/26/2018	BOS	vs	BAL	W 19-3	45	22	9	0	5	19	3	0	7	1	0	48	46	14	0	0	0	1	.489	.521	1.022	1.543
3	Red Sox	19	1	8/10/2018	BOS	@	BAL	W 19-12	41	16	5	1	3	18	10	1	6	1	0	53	32	9	0	1	1	1	.390	.509	.780	1.290
4	Rays	19	1	7/14/2018	TBR	@	MIN	W 19-6	44	20	5	1	3	19	4	1	7	0	1	50	36	9	0	1	1	0	.455	.500	.818	1.318
5	Indians	19	1	7/11/2018	CLE	vs	CIN	W 19-4	42	19	1	0	4	19	7	0	6	0	0	49	32	5	0	0	0	2	.452	.531	.762	1.293
6	Rangers	18	1	9/2/2018	TEX	vs	MIN	W 18-4	42	19	6	1	6	15	2	3	8	0	0	48	45	13	0	1	0	1	.452	.500	1.071	1.571
7	Rangers	17	1	8/2/2018	TEX	vs	BAL	W 17-8	41	18	6	0	3	16	10	0	8	0	0	51	33	9	0	0	0	0	.439	.549	.805	1.354
8	Orioles	17	1	5/13/2018	BAL	vs	TBR	W 17-1	44	19	3	1	4	17	5	0	5	0	0	49	36	8	0	0	0	0	.432	.490	.818	1.308
9	Indians	16	1	7/21/2018	CLE	@	TEX	W 16-3	47	21	8	1	3	15	2	1	3	0	0	50	40	12	0	0	0	0	.447	.480	.851	1.331
10	Athletics	16	1	6/1/2018	OAK	@	KCR	W 16-0	41	16	1	1	4	16	5	0	11	0	0	47	31	6	0	1	0	1	.390	.447	.756	1.203
11	Astros	16	1	5/7/2018	HOU	@	OAK	W 16-2	45	20	5	0	3	14	6	0	4	0	0	51	34	8	0	0	0	2	.444	.510	.756	1.265
12	Athletics	16	1	4/11/2018	OAK	@	LAD	W 16-6	49	21	3	0	3	15	1	0	9	0	0	50	33	6	0	0	0	0	.429	.440	.673	1.113
13	Indians	15	1	9/15/2018	CLE	vs	DET	W 15-0	42	18	3	1	3	14	6	2	2	0	0	52	32	7	0	2	0	1	.429	.500	.762	1.262
14	Twins	15	1	8/16/2018	MIN	vs	DET	W 15-8	38	15	3	0	3	15	4	1	10	0	1	45	27	6	0	2	0	0	.395	.444	.711	1.155
15	Red Sox	15	1	8/2/2018	BOS	vs	NYY	W 15-7	44	19	7	0	3	15	6	0	4	4	0	50	35	10	0	0	0	0	.432	.500	.795	1.295
16	Orioles	15	1	7/27/2018	BAL	vs	TBR	W 15-5	39	15	2	0	2	13	8	0	4	0	0	47	23	4	0	0	0	1	.385	.489	.590	1.079
17	Athletics	15	1	7/23/2018	OAK	@	TEX	W 15-3	44	18	6	0	4	15	4	1	7	0	0	49	36	10	0	0	0	0	.409	.469	.818	1.288
18	Red Sox	15	1	7/7/2018	BOS	@	KCR	W 15-4	40	16	5	0	1	15	13	0	8	3	0	54	24	6	0	1	1	1	.400	.537	.600	1.137
19	Indians	15	1	7/1/2018	CLE	@	OAK	W 15-3	46	20	11	0	2	15	3	1	10	0	0	51	37	13	1	0	0	0	.435	.480	.804	1.284
20	Royals	15	1	5/8/2018	KCR	@	BAL	W 15-7	43	20	0	0	5	15	3	0	6	0	0	48	35	5	0	2	0	2	.465	.479	.814	1.293
21	Blue Jays	15	1	4/18/2018	TOR	vs	KCR	W 15-5	40	15	4	1	3	13	7	1	9	0	0	48	30	8	0	0	0	1	.375	.479	.750	1.229
22	Indians	14	1	9/28/2018	CLE	@	KCR	W 14-6	44	16	4	0	2	12	3	0	3	0	0	47	26	6	0	0	0	0	.364	.404	.591	.995
23	Rays	14	1	9/7/2018	TBR	vs	BAL	W 14-2	32	10	1	0	4	13	11	0	6	1	1	44	23	5	0	1	0	0	.313	.477	.719	1.196
24	Red Sox	14	1	8/29/2018	BOS	vs	MIA	W 14-6	37	16	4	1	2	13	3	0	6	0	0	41	28	7	1	0	1	2	.432	.475	.757	1.232
25	Astros	14	1	8/4/2018	HOU	@	LAD	W 14-0	38	13	6	0	3	14	5	1	7	1	0	46	28	9	1	1	2	0	.342	.422	.737	1.159