The Brooklyn Dodgers had the highest run differential by a team in 1955, with a differential of 207 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	207	1955	154	.641	98	55	5,193	857	1,406	230	44	201	800	674	41	718	79	56	6,037	2,327	475	75	54	62	132	.271	.356	.448	.804
2	Yankees	192	1955	154	.623	96	58	5,161	761	1,342	179	55	175	717	607	46	655	55	25	5,942	2,156	409	79	49	48	99	.260	.340	.418	.758
3	White Sox	168	1955	155	.591	91	63	5,220	725	1,401	204	36	116	677	568	58	595	69	45	6,000	2,025	356	111	43	40	117	.268	.344	.388	.732
4	Tigers	117	1955	154	.513	79	75	5,283	775	1,407	211	38	130	724	638	21	581	41	22	6,070	2,084	379	71	57	42	130	.266	.344	.394	.739
5	Red Sox	103	1955	154	.545	84	70	5,273	755	1,392	241	39	137	709	707	29	730	43	17	6,131	2,122	417	69	53	44	125	.264	.351	.402	.753
6	Indians	97	1955	154	.604	93	61	5,146	698	1,325	195	31	148	657	723	35	715	28	24	6,050	2,026	374	87	59	36	112	.257	.349	.394	.743
7	Redlegs	77	1955	154	.487	75	79	5,270	761	1,424	216	28	181	726	556	33	657	51	36	5,978	2,239	425	76	43	50	104	.270	.341	.425	.766
8	Braves	75	1955	154	.552	85	69	5,277	743	1,377	219	55	182	699	504	28	735	42	27	5,920	2,252	456	72	39	67	113	.261	.326	.427	.753
9	Giants	29	1955	154	.519	80	74	5,288	702	1,377	173	34	169	643	497	36	581	38	22	5,940	2,125	376	69	50	44	108	.260	.325	.402	.727
10	Phillies	9	1955	154	.500	77	77	5,092	675	1,300	214	50	132	631	652	24	673	44	32	5,864	2,010	396	53	43	39	139	.255	.340	.395	.735
11	Cubs	-87	1955	154	.471	72	81	5,214	626	1,287	187	55	164	597	428	22	806	37	35	5,766	2,076	406	69	33	45	107	.247	.305	.398	.703
12	Cardinals	-103	1955	154	.442	68	86	5,266	654	1,375	228	36	143	608	458	31	597	64	59	5,855	2,104	407	56	44	53	122	.261	.321	.400	.721
13	Senators	-191	1955	154	.344	53	101	5,142	598	1,277	178	54	80	566	537	36	651	25	32	5,832	1,803	312	79	38	23	127	.248	.322	.351	.672
14	Pirates	-207	1955	154	.390	60	94	5,173	560	1,262	210	60	91	532	471	21	652	22	22	5,790	1,865	361	93	32	64	132	.244	.308	.361	.668
15	Orioles	-214	1955	156	.370	57	97	5,257	540	1,263	177	39	54	503	562	19	740	34	46	5,935	1,680	270	70	27	31	127	.240	.314	.320	.634
16	Athletics	-273	1955	155	.409	63	91	5,335	638	1,395	189	46	121	592	462	26	718	22	36	5,915	2,039	356	58	34	34	146	.261	.321	.382	.704