The Baltimore Orioles had the highest run differential by a team in 1970, with a differential of 218 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Orioles	218	1970	162	.667	108	54	5,545	792	1,424	213	25	179	748	717	44	952	84	39	6,416	2,224	417	64	46	64	110	.257	.344	.401	.745
2	Twins	139	1970	162	.605	98	64	5,483	744	1,438	230	41	153	694	501	42	905	57	52	6,143	2,209	424	79	38	65	132	.262	.327	.403	.730
3	Cubs	127	1970	162	.519	84	78	5,491	806	1,424	228	44	179	761	607	20	844	39	16	6,229	2,277	451	75	36	65	110	.259	.333	.415	.748
4	Reds	94	1970	162	.630	102	60	5,540	775	1,498	253	45	191	726	547	29	984	115	52	6,222	2,414	489	58	48	70	119	.270	.336	.436	.772
5	Athletics	85	1970	162	.549	89	73	5,376	678	1,338	208	24	171	630	584	36	977	131	68	6,105	2,107	403	73	36	55	121	.249	.325	.392	.717
6	Yankees	68	1970	163	.574	93	69	5,492	680	1,381	208	41	111	627	588	25	808	105	61	6,211	2,004	360	60	46	48	115	.251	.324	.365	.689
7	Pirates	65	1970	162	.549	89	73	5,637	729	1,522	235	70	130	676	444	44	871	66	34	6,231	2,287	435	53	53	82	117	.270	.325	.406	.731
8	Dodgers	65	1970	161	.540	87	74	5,606	749	1,515	233	67	87	695	541	24	841	138	57	6,293	2,143	387	72	50	67	113	.270	.334	.382	.717
9	Mets	65	1970	162	.512	83	79	5,443	695	1,358	211	42	120	640	684	26	1,062	118	54	6,275	2,013	373	74	48	60	139	.249	.333	.370	.703
10	Red Sox	64	1970	162	.537	87	75	5,535	786	1,450	252	28	203	743	594	40	855	50	48	6,250	2,367	483	34	47	47	137	.262	.335	.428	.763
11	Giants	5	1970	162	.531	86	76	5,578	831	1,460	257	35	165	773	729	56	1,005	83	27	6,469	2,282	457	66	40	95	144	.262	.351	.409	.760
12	Angels	1	1970	162	.531	86	76	5,532	631	1,391	197	40	114	598	447	29	922	69	27	6,114	2,010	351	69	37	56	118	.251	.309	.363	.672
13	Cardinals	-3	1970	162	.469	76	86	5,689	744	1,497	218	51	113	688	569	26	961	117	47	6,376	2,156	382	52	40	65	138	.263	.331	.379	.710
14	Astros	-19	1970	162	.488	79	83	5,574	744	1,446	250	47	129	694	598	27	911	114	41	6,305	2,177	426	63	43	81	144	.259	.332	.391	.722
15	Indians	-26	1970	162	.469	76	86	5,463	649	1,358	197	23	183	617	503	37	909	25	36	6,124	2,150	403	76	45	42	119	.249	.314	.394	.707
16	Braves	-36	1970	162	.469	76	86	5,546	736	1,495	215	24	160	692	522	38	736	58	34	6,202	2,238	399	54	42	72	140	.270	.334	.404	.738
17	Senators	-63	1970	162	.432	70	92	5,460	626	1,302	184	28	138	583	635	46	989	72	42	6,223	1,956	350	44	38	68	133	.238	.321	.358	.679
18	Tigers	-65	1970	162	.488	79	83	5,377	666	1,282	207	38	148	619	656	34	825	29	30	6,199	2,009	393	83	49	56	134	.238	.322	.374	.696
19	Royals	-94	1970	162	.401	65	97	5,503	611	1,341	202	41	97	572	514	21	958	97	53	6,128	1,916	340	63	27	42	126	.244	.309	.348	.657
20	Padres	-107	1970	162	.389	63	99	5,494	681	1,353	208	36	172	629	500	39	1,164	60	45	6,145	2,149	416	83	29	46	111	.246	.312	.391	.703
21	Expos	-120	1970	162	.451	73	89	5,411	687	1,284	211	35	136	646	659	39	972	65	45	6,251	1,973	382	107	35	64	106	.237	.323	.365	.687
22	Phillies	-136	1970	161	.453	73	88	5,456	594	1,299	224	58	101	553	519	25	1,066	72	64	6,099	1,942	383	62	37	59	133	.238	.305	.356	.661
23	Brewers	-138	1970	163	.401	65	97	5,395	613	1,305	202	24	126	571	592	36	985	91	73	6,170	1,933	352	115	32	54	132	.242	.319	.358	.678
24	White Sox	-189	1970	162	.346	56	106	5,514	633	1,394	192	20	123	587	477	42	872	53	33	6,132	1,995	335	51	48	41	132	.253	.315	.362	.676