Since 1980, the New York Yankees have the most wins by a team, with 4,028 wins.

Interpreted as:

teams with most regular-season wins since 1980

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	4,028	3,091	.566	7,122	244,036	35,635	64,782	11,966	1,016	8,648	33,946	26,392	2,335	46,115	4,384	1,655	276,265	104,724	21,630	1,354	2,148	1,665	5,937	.265	.340	.429	.769
2	Dodgers	3,898	3,232	.547	7,132	242,207	31,482	62,249	11,135	1,226	7,050	29,824	23,578	2,066	47,543	4,899	2,042	272,754	96,986	19,411	2,993	1,910	2,164	5,122	.257	.326	.400	.726
3	Braves	3,816	3,300	.536	7,119	242,212	32,181	62,471	11,822	1,163	7,471	30,529	23,742	1,920	48,269	4,145	1,972	272,508	99,032	20,456	2,804	1,830	2,115	5,417	.258	.327	.409	.736
4	Red Sox	3,810	3,319	.534	7,130	247,284	35,566	67,209	14,178	1,249	7,643	33,790	25,135	2,321	46,092	3,337	1,476	278,327	106,814	23,070	1,414	2,173	1,867	6,043	.272	.342	.432	.774
5	Cardinals	3,795	3,321	.533	7,121	241,909	32,181	63,157	11,968	1,436	6,426	30,425	23,870	2,198	46,532	5,490	2,212	272,831	97,275	19,830	2,827	2,027	2,223	5,308	.261	.330	.402	.733
6	Astros	3,694	3,437	.518	7,132	242,566	31,736	62,542	12,075	1,381	6,772	30,051	23,338	2,309	47,413	5,257	2,191	272,841	97,695	20,228	2,627	2,001	2,042	5,270	.258	.326	.403	.729
7	Giants	3,649	3,482	.512	7,132	242,534	31,146	61,844	11,661	1,513	6,627	29,451	23,520	2,023	48,342	4,103	1,993	272,918	96,412	19,801	2,898	1,943	2,482	5,269	.255	.324	.398	.721
8	Athletics	3,629	3,501	.509	7,130	242,307	32,857	61,287	11,711	1,059	7,599	31,114	25,488	2,199	48,244	4,574	1,764	273,619	97,913	20,369	1,532	2,093	1,283	5,576	.253	.327	.404	.731
9	Blue Jays	3,627	3,499	.509	7,129	244,548	33,384	63,741	12,852	1,379	7,983	31,715	22,806	2,346	46,922	4,412	1,800	273,001	103,300	22,214	1,281	2,020	1,326	5,527	.261	.327	.422	.750
10	Guardians	3,612	3,503	.508	7,117	243,734	33,607	64,406	12,439	1,228	7,192	31,844	23,978	2,249	45,541	4,960	2,017	273,946	100,877	20,859	1,759	2,226	1,547	5,624	.264	.333	.414	.747
11	Mets	3,598	3,522	.505	7,122	241,494	30,990	61,294	11,613	1,223	6,826	29,365	23,332	2,257	47,986	4,734	1,882	271,692	95,831	19,662	2,656	1,953	2,209	5,171	.254	.323	.397	.720
12	Angels	3,583	3,547	.503	7,130	243,318	32,559	63,306	11,521	1,182	7,218	30,791	22,710	2,155	45,743	4,465	2,120	272,202	98,845	19,921	2,042	1,977	1,625	5,614	.260	.326	.406	.733
13	Phillies	3,571	3,555	.501	7,129	243,292	31,889	62,201	11,986	1,559	6,926	30,190	24,217	2,194	49,853	4,878	1,622	274,070	98,083	20,471	2,476	1,891	2,220	5,054	.256	.326	.403	.729
14	Brewers	3,540	3,588	.497	7,130	242,780	32,464	62,515	12,039	1,374	7,298	30,825	23,222	2,392	49,118	4,977	2,055	272,675	99,196	20,711	2,305	1,976	1,728	5,320	.257	.326	.409	.735
15	White Sox	3,504	3,617	.492	7,127	242,793	32,502	63,190	11,529	1,311	7,435	30,925	22,012	2,223	46,082	4,530	2,034	271,069	99,646	20,275	1,996	2,045	1,412	5,498	.260	.325	.410	.735
16	Nationals	3,494	3,629	.491	7,126	241,322	30,425	61,620	12,308	1,435	6,371	28,699	22,420	2,228	47,679	5,637	2,209	270,747	95,911	20,114	2,902	1,875	2,201	5,178	.255	.322	.397	.720
17	Rangers	3,493	3,631	.490	7,128	244,765	34,058	64,542	12,217	1,286	7,935	32,301	22,728	2,120	48,083	4,358	1,913	273,338	103,136	21,438	1,665	2,060	1,443	5,387	.264	.329	.421	.750
18	Cubs	3,481	3,634	.489	7,122	243,055	31,603	62,196	11,811	1,425	7,332	29,934	22,554	2,152	50,010	4,229	1,878	272,246	98,853	20,568	2,656	1,829	2,008	5,153	.256	.322	.407	.729
19	Reds	3,481	3,649	.488	7,135	241,919	31,469	61,561	11,872	1,260	7,253	29,765	23,593	2,289	50,552	5,528	2,138	272,470	97,712	20,385	2,780	1,889	2,032	5,052	.254	.324	.404	.728
20	Twins	3,469	3,658	.487	7,129	244,620	32,600	64,480	12,584	1,490	6,643	30,814	22,323	2,221	45,734	3,923	1,876	272,623	99,973	20,717	1,393	2,066	1,481	5,856	.264	.328	.409	.737
21	Mariners	3,444	3,681	.483	7,127	243,261	31,835	62,481	11,732	1,137	7,383	30,260	23,146	2,273	47,656	4,672	2,007	272,346	98,636	20,252	1,738	1,928	1,573	5,304	.257	.325	.405	.730
22	Padres	3,443	3,690	.483	7,135	241,561	29,877	60,800	11,073	1,359	6,161	28,177	23,256	1,820	49,300	5,026	2,065	271,196	93,074	18,593	2,668	1,891	2,059	5,290	.252	.320	.385	.705
23	Tigers	3,423	3,703	.480	7,127	244,149	32,846	63,595	11,789	1,610	7,554	31,236	23,259	1,986	49,196	3,711	1,892	272,970	101,266	20,953	1,555	2,021	1,398	5,360	.260	.327	.415	.742
24	Orioles	3,423	3,695	.481	7,122	243,742	32,542	63,186	11,852	982	8,022	31,012	23,125	2,121	45,929	3,586	1,603	272,491	101,068	20,856	1,517	1,986	1,376	5,775	.259	.326	.415	.741
25	Royals	3,320	3,799	.466	7,120	243,940	31,236	64,173	12,223	1,741	5,909	29,554	20,144	2,113	44,028	5,440	2,116	270,022	97,605	19,873	1,731	2,094	1,357	5,479	.263	.322	.400	.722