The San Francisco Giants have the most wins by a team, with 11,563 wins.

Interpreted as:

the most regular-season wins by a team in MLB history

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Giants	11,563	10,032	.535	21,758	742,584	100,615	195,332	31,333	7,035	15,575	90,089	68,260	5,670	99,469	16,512	3,142	831,186	287,460	53,943	11,662	3,010	4,016	10,172	.263	.329	.387	.716
2	Dodgers	11,455	10,079	.532	21,673	738,455	97,826	192,929	31,031	7,003	14,109	88,050	68,849	5,145	100,241	17,333	3,547	828,352	280,293	52,143	12,772	3,055	3,729	9,932	.261	.327	.380	.707
3	Cubs	11,348	10,781	.513	22,290	762,804	102,628	199,782	33,729	7,356	15,236	88,217	68,526	5,281	104,955	15,777	3,067	852,539	293,931	56,321	13,026	2,902	3,518	9,956	.262	.326	.385	.711
4	Braves	11,129	10,967	.504	22,250	761,796	99,452	197,856	32,089	6,298	15,044	86,501	67,454	5,062	100,027	14,088	3,063	849,867	287,673	53,431	12,681	2,874	3,651	10,374	.260	.323	.378	.701
5	Reds	10,952	10,783	.504	21,874	745,322	98,166	194,202	32,357	7,557	14,309	87,312	66,667	5,503	102,147	18,152	3,403	833,356	284,600	54,223	12,661	3,035	3,645	9,708	.261	.325	.382	.707
6	Pirates	10,851	10,842	.500	21,833	747,875	97,130	196,862	32,338	8,933	12,244	86,640	64,280	5,526	99,481	15,672	3,266	833,475	283,798	53,515	12,557	3,114	3,696	10,045	.263	.325	.379	.704
7	Yankees	10,797	8,163	.569	19,048	649,203	92,554	172,359	28,609	5,492	17,298	85,998	68,534	4,922	94,729	11,640	2,800	735,529	263,846	51,399	9,594	3,276	2,827	10,675	.265	.339	.406	.745
8	Cardinals	10,521	9,989	.513	20,641	706,057	92,345	187,631	31,805	7,049	12,847	84,410	64,152	5,192	98,056	15,010	3,612	790,507	272,075	51,701	11,971	3,135	3,775	10,127	.266	.330	.385	.715
9	Phillies	10,226	11,341	.474	21,682	741,887	96,272	193,182	33,393	6,677	14,176	86,497	67,701	5,409	105,240	14,948	2,911	829,922	282,457	54,246	11,914	3,011	3,739	9,856	.260	.326	.381	.706
10	Red Sox	9,973	9,281	.518	19,337	661,809	90,311	176,604	33,100	5,597	14,585	83,748	66,777	4,799	95,453	9,628	2,546	747,317	264,653	53,282	10,594	3,338	2,996	11,542	.267	.337	.400	.737
11	Guardians	9,872	9,383	.513	19,346	659,394	87,464	174,574	31,126	5,496	13,905	80,833	62,583	4,829	94,502	11,900	3,384	741,619	258,407	50,527	11,461	3,352	2,544	10,519	.265	.331	.392	.723
12	Tigers	9,698	9,580	.503	19,371	660,577	88,949	174,529	29,563	6,294	14,567	81,909	65,511	4,441	96,613	11,287	2,935	744,641	260,381	50,424	11,009	3,103	2,446	10,705	.264	.333	.394	.727
13	White Sox	9,604	9,636	.499	19,343	654,953	84,035	170,073	28,185	5,550	12,275	77,245	62,063	5,246	91,955	13,613	3,482	737,847	246,183	46,010	12,367	3,218	2,461	10,510	.260	.327	.376	.703
14	Athletics	9,348	9,875	.486	19,310	654,512	85,231	168,475	29,173	5,332	14,126	78,535	64,471	4,727	98,916	12,098	3,205	737,492	250,690	48,631	10,681	3,101	2,267	10,607	.257	.327	.383	.710
15	Twins	9,274	9,975	.482	19,358	660,373	85,111	173,189	29,739	6,331	11,999	78,355	62,326	5,153	94,364	12,008	3,078	741,204	251,587	48,069	10,189	3,163	2,661	10,963	.262	.329	.381	.710
16	Orioles	9,133	10,104	.475	19,347	657,165	83,545	169,579	29,304	4,909	14,421	77,242	63,248	4,471	98,215	10,540	2,778	738,512	251,964	48,634	10,530	3,098	2,574	10,832	.258	.326	.383	.709
17	Angels	5,034	5,135	.495	10,172	345,124	44,001	88,307	15,265	1,808	9,193	41,403	32,273	2,817	62,600	6,042	3,097	386,517	134,767	26,266	3,536	2,767	2,482	7,870	.256	.322	.390	.713
18	Astros	5,026	4,981	.502	10,012	339,776	42,698	86,612	15,882	2,171	8,410	40,183	32,309	2,893	62,819	7,146	3,130	381,716	132,066	26,463	4,027	2,711	3,144	7,396	.255	.323	.389	.711
19	Mets	4,838	5,161	.484	10,007	338,586	41,294	84,610	15,115	1,814	8,564	38,881	32,366	2,851	64,850	5,873	2,734	380,404	129,045	25,493	3,986	2,615	3,137	7,446	.250	.318	.381	.699
20	Rangers	4,835	5,320	.476	10,161	346,880	45,723	89,483	15,951	1,891	10,178	43,202	32,849	2,693	65,068	5,931	2,845	388,212	139,750	28,020	2,963	2,827	2,250	7,791	.258	.325	.403	.727
21	Brewers	4,325	4,548	.487	8,877	301,337	39,470	77,170	14,383	1,755	8,693	37,392	28,999	2,706	58,803	5,963	2,727	338,616	121,142	24,831	3,160	2,414	2,158	6,606	.256	.325	.402	.727
22	Nationals	4,281	4,588	.483	8,873	300,108	37,171	76,153	14,686	1,788	7,591	34,935	28,219	2,618	57,083	6,538	2,771	337,105	117,188	24,065	3,877	2,283	2,880	6,490	.254	.321	.390	.712
23	Royals	4,227	4,639	.477	8,868	303,327	38,793	79,656	14,891	2,284	6,997	36,611	25,969	2,455	52,035	7,077	2,893	336,781	120,106	24,172	2,364	2,666	1,865	6,772	.263	.323	.396	.719
24	Padres	4,149	4,728	.467	8,879	300,147	35,979	74,850	13,246	1,757	7,247	33,835	28,575	2,122	59,371	5,999	2,603	336,796	113,351	22,250	3,709	2,243	2,685	6,494	.249	.317	.378	.695
25	Blue Jays	3,777	3,806	.498	7,586	259,903	35,059	67,582	13,507	1,491	8,239	33,253	24,098	2,423	48,869	4,568	1,962	290,043	108,788	23,237	1,497	2,122	1,397	5,916	.260	.326	.419	.745