what pitcher leads the mlb in strikeouts in the 2nd inning

Randy Johnson has struck out the most career hitters in the 2nd inning, with 764 strikeouts.

NAMESOGHHRBBHBPIBBK/BB
1Randy Johnson
R. Johnson
764
603
435
60
204
31
1
3.75
2Roger Clemens
R. Clemens
749
704
582
59
227
31
3
3.30
3Nolan Ryan
N. Ryan
665
609
432
44
307
17
1
2.17
4Justin Verlander
J. Verlander
596
554
436
44
120
16
2
4.97
5Max Scherzer
M. Scherzer
572
470
373
48
103
17
4
5.55
6CC Sabathia
CC Sabathia
533
559
495
53
166
21
3
3.21
7Greg Maddux
G. Maddux
529
736
630
56
113
12
20
4.68
8Clayton Kershaw
C. Kershaw
512
450
314
38
96
5
3
5.33
9Zack Greinke
Z. Greinke
507
540
495
47
129
6
4
3.93
10John Smoltz
J. Smoltz
504
481
398
39
149
3
3
3.38
11Pedro Martinez
P. Martinez
496
407
301
42
108
20
5
4.59
12Mike Mussina
M. Mussina
470
534
537
55
137
9
1
3.43
13Frank Tanana
F. Tanana
466
602
508
53
169
20
8
2.76
14Curt Schilling
C. Schilling
452
436
379
38
73
4
0
6.19
15Tom Glavine
T. Glavine
452
678
598
50
188
4
18
2.40
16Javier Vazquez
J. Vazquez
450
443
412
55
131
15
9
3.44
17Jon Lester
J. Lester
441
450
436
56
146
13
3
3.02
18Jamie Moyer
J. Moyer
435
641
588
78
168
22
4
2.59
19A.J. Burnett
A.J. Burnett
430
430
371
48
182
19
4
2.36
20Charlie Morton
C. Morton
424
405
328
39
158
27
5
2.68
21Cole Hamels
C. Hamels
423
419
336
47
104
20
5
4.07
22David Cone
D. Cone
418
420
335
41
156
20
5
2.68
23Bartolo Colon
B. Colon
415
546
546
68
157
5
5
2.64
24Bert Blyleven
B. Blyleven
415
543
469
38
145
20
2
2.86
25Felix Hernandez
F. Hernandez
411
416
356
36
117
11
1
3.51
StatMuse has event-level data for strikeouts going back to the 1974 season.
Some of the information used here was obtained free of charge from Retrosheet.

More Mariners Stats

Team Rankings

HR

238

3rd

R

766

9th

SO

1,426

7th

ERA

3.87

13th

2025 Division Standings
TEAMWLPCTGB
Mariners Mariners
90
72
.556
Astros Astros
87
75
.537
3.0
Rangers Rangers
81
81
.500
9.0
Athletics Athletics
76
86
.469
14.0
Angels Angels
72
90
.444
18.0
Schedule
DATEMATCHUPTIME (ET)
Thu
3/26
CLE CLE
@
SEA SEA
10:10 PM
Fri
3/27
CLE CLE
@
SEA SEA
9:40 PM
Sat
3/28
CLE CLE
@
SEA SEA
9:40 PM
Sun
3/29
CLE CLE
@
SEA SEA
4:10 PM
Mon
3/30
NYY NYY
@
SEA SEA
9:40 PM
Last Game
SEA Mariners

3 - 4

3

Final

4

TOR Blue Jays

4 - 3

Mon 20 Oct 2025

MLB 2025 Batting Leaders

MLB 2025 Pitching Leaders

MLB Fantasy 2025

MLB 2025 Betting

MLB 2025 Division Standings

NL EastWLPCTGB
Phillies Phillies
96
66
.593
Mets Mets
83
79
.512
13.0
NL CentralWLPCTGB
Brewers Brewers
97
65
.599
Cubs Cubs
92
70
.568
5.0
NL WestWLPCTGB
Dodgers Dodgers
93
69
.574
Padres Padres
90
72
.556
3.0
AL EastWLPCTGB
Blue Jays Blue Jays
94
68
.580
Yankees Yankees
94
68
.580
AL CentralWLPCTGB
Guardians Guardians
88
74
.543
Tigers Tigers
87
75
.537
1.0
AL WestWLPCTGB
Mariners Mariners
90
72
.556
Astros Astros
87
75
.537
3.0

MLB 2025 Scores & Schedule

Scores

DATEMATCHUPSCORE
Tue
9/16
CIN CIN
@
STL STL
6-2
Tue
9/16
ATL ATL
@
WSH WSH
9-4
Tue
9/16
ATH ATH
@
BOS BOS
4-5
Tue
9/16
TOR TOR
@
TBR TBR
1-2
Tue
9/16
SEA SEA
@
KCR KCR
5-7

Schedule

DATEMATCHUPTIME (ET)
Wed
3/25
NYY NYY
@
SFG SFG
8:05 PM
Thu
3/26
LAA LAA
@
HOU HOU
4:00 AM
Thu
3/26
AZ AZ
@
LAD LAD
4:00 AM
Thu
3/26
WSH WSH
@
CHC CHC
4:00 AM
Thu
3/26
CWS CWS
@
MIL MIL
2:10 PM