Since 2021, the Colorado Rockies have lost the most games by a team, with 433 losses.

Interpreted as:

What team has most regular-season loses since 2021?

	TEAM	L	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	433	271	.615	704	.385	23,748	3,019	5,843	1,222	139	720	2,895	2,000	247	6,406	309	112	26,263	9,503	2,081	95	173	67	524	.246	.309	.400	.709
2	Athletics	418	288	.592	706	.408	23,440	2,781	5,390	1,080	81	774	2,650	2,151	306	6,197	441	107	26,152	8,954	1,935	89	166	52	496	.230	.301	.382	.683
3	Nationals	416	289	.590	705	.410	23,612	2,940	5,908	1,163	93	664	2,792	2,062	321	5,338	535	177	26,268	9,249	1,920	114	159	74	561	.250	.317	.392	.709
4	White Sox	411	294	.583	705	.417	23,709	2,827	5,713	1,122	55	689	2,704	1,929	258	5,964	336	95	26,120	9,012	1,866	80	144	47	535	.241	.303	.380	.683
5	Pirates	410	296	.581	706	.419	23,476	2,742	5,458	1,054	122	641	2,609	2,248	242	6,299	428	135	26,230	8,679	1,817	96	168	71	444	.232	.304	.370	.674
6	Marlins	399	304	.568	703	.432	23,643	2,741	5,724	1,065	97	669	2,611	1,891	255	6,136	485	140	26,039	8,990	1,831	92	158	75	525	.242	.303	.380	.684
7	Royals	395	311	.559	706	.441	23,655	2,930	5,825	1,118	157	668	2,812	1,862	247	5,510	572	165	26,094	9,261	1,943	101	229	58	418	.246	.305	.392	.697
8	Angels	392	312	.557	704	.443	23,564	2,948	5,591	1,039	101	856	2,815	2,053	301	6,425	385	143	26,143	9,400	1,996	80	145	100	467	.237	.305	.399	.704
9	Rangers	382	324	.541	706	.459	23,823	3,092	5,752	1,062	83	833	2,956	2,126	233	5,993	461	127	26,386	9,479	1,978	44	160	62	423	.241	.308	.398	.706
10	Diamondbacks	379	326	.538	705	.462	23,738	3,299	5,836	1,229	147	771	3,132	2,382	284	5,746	481	112	26,762	9,672	2,147	141	217	73	468	.246	.319	.407	.727
11	Reds	373	333	.528	706	.472	23,585	3,186	5,705	1,156	104	811	3,042	2,260	396	6,329	546	169	26,490	9,502	2,071	87	162	48	478	.242	.317	.403	.720
12	Tigers	361	345	.511	706	.489	23,637	2,892	5,600	1,051	148	684	2,778	2,047	229	6,383	317	101	26,143	8,999	1,883	48	182	43	453	.237	.302	.381	.683
13	Cubs	359	346	.509	705	.491	23,664	3,249	5,783	1,120	130	814	3,098	2,339	337	6,247	552	150	26,615	9,605	2,064	97	178	70	473	.244	.319	.406	.725
14	Orioles	357	347	.507	704	.493	23,784	3,141	5,811	1,193	108	844	3,011	2,086	283	6,074	402	116	26,390	9,752	2,145	55	182	54	428	.244	.311	.410	.721
15	Twins	353	351	.501	704	.499	23,753	3,173	5,800	1,201	89	877	3,023	2,264	359	6,174	273	84	26,595	9,810	2,167	40	179	60	525	.244	.317	.413	.730
16	Red Sox	350	357	.495	707	.505	24,227	3,367	6,222	1,440	92	822	3,213	2,168	292	6,237	402	124	26,910	10,312	2,354	45	178	102	486	.257	.323	.426	.749
17	Cardinals	336	369	.477	705	.523	23,801	3,139	5,933	1,179	80	821	3,009	2,248	319	5,657	412	116	26,639	9,735	2,080	81	190	79	468	.249	.320	.409	.729
18	Guardians	333	370	.474	703	.526	23,538	3,009	5,747	1,139	105	696	2,852	2,020	308	5,295	566	140	26,143	9,184	1,940	80	197	131	472	.244	.310	.390	.700
19	Blue Jays	330	375	.468	705	.532	23,919	3,270	6,129	1,260	72	859	3,140	2,258	273	5,401	354	114	26,663	10,110	2,191	49	164	70	545	.256	.325	.423	.748
20	Mets	328	377	.465	705	.535	23,457	3,140	5,762	1,098	93	830	3,004	2,251	441	5,759	382	93	26,398	9,536	2,021	86	163	84	504	.246	.321	.407	.728
21	Padres	328	375	.467	703	.533	23,610	3,182	5,855	1,161	78	780	3,038	2,442	252	5,421	457	132	26,602	9,512	2,019	115	183	106	518	.248	.323	.403	.726
22	Giants	326	379	.462	705	.538	23,608	3,131	5,633	1,134	95	831	2,996	2,405	309	6,352	284	80	26,581	9,450	2,060	78	181	97	493	.239	.315	.400	.715
23	Mariners	321	383	.456	704	.544	23,462	3,077	5,424	1,040	58	867	2,953	2,464	419	6,617	458	126	26,552	9,181	1,965	44	163	55	446	.231	.313	.391	.705
24	Phillies	315	390	.447	705	.553	23,883	3,333	6,022	1,182	114	882	3,198	2,309	271	6,066	524	114	26,731	10,078	2,178	84	184	101	472	.252	.323	.422	.745
25	Rays	311	394	.441	705	.559	23,719	3,227	5,768	1,196	103	793	3,065	2,263	318	6,314	602	189	26,489	9,549	2,092	30	159	62	403	.243	.316	.403	.718