Frank Thomas has launched the most career home runs for the White Sox, with 448 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Frank Thomas F. Thomas	448	1,959	6,956	1,327	2,136	447	11	1,465	1,466	71	1,165	32	23	8,602	3,949	906	0	109	162	190	.307	.427	.568	.995	1721	670.2	.424	159	642.9
2	Paul Konerko P. Konerko	432	2,268	8,169	1,141	2,292	406	8	1,383	904	101	1,349	9	3	9,258	4,010	846	1	83	80	271	.281	.356	.491	.847	1402	286	.364	120	226.3
3	Al Kaline A. Kaline	399	2,834	10,116	1,622	3,007	498	75	1,582	1,277	55	1,020	137	65	11,597	4,852	972	45	104	131	271	.297	.376	.480	.855	1825	555.2	.378	134	453.6
4	Norm Cash N. Cash	377	2,089	6,705	1,045	1,820	241	41	1,104	1,043	90	1,091	43	30	7,910	3,274	659	17	55	112	139	.271	.374	.488	.862	1274	427.7	.382	139	355.6
5	Miguel Cabrera M. Cabrera	373	2,077	7,662	1,102	2,332	444	7	1,358	936	49	1,513	23	10	8,724	3,909	824	0	77	168	277	.304	.380	.510	.890	1443	425.9	.378	139	395.4
6	Hank Greenberg H. Greenberg	306	1,269	4,791	975	1,528	366	69	1,200	748	12	771	58		5,586	2,950	741	35			50	.319	.412	.616	1.028	1200	526.1	.457	156	425.4
7	Magglio Ordonez M. Ordonez	294	1,848	6,978	1,076	2,156	426	21	1,236	651	45	852	94	50	7,742	3,506	741	3	65	36	242	.309	.369	.502	.871	1245	292.4	.375	126	258.1
8	Willie Horton W. Horton	262	1,515	5,405	671	1,490	211	31	886	469	49	945	14	29	5,978	2,549	504	11	44	78	141	.276	.337	.472	.808	845	219	.359	127	174.8
9	Rudy York R. York	254	1,370	5,077	778	1,414	254	46	997	677	11	727	35		5,787	2,522	554	22			127	.279	.365	.497	.861	942	281.7	.396	125	185.5
10	Cecil Fielder C. Fielder	245	982	3,674	558	947	141	4	758	519	27	926	2	3	4,252	1,831	390	0	32	66	113	.258	.351	.498	.849	649	147.5	.369	124	120.8
11	Lou Whitaker L. Whitaker	244	2,390	8,570	1,386	2,369	420	65	1,084	1,197	20	1,099	143	75	9,967	3,651	729	89	91	79	143	.276	.363	.426	.789	1388	254.5	.353	118	208.3
12	José Abreu J. Abreu	243	1,270	4,954	697	1,445	303	16	863	386	117	1,088	11	5	5,506	2,509	562	0	49	56	167	.292	.354	.506	.860	866	217.6	.364	133	211.5
13	Harold Baines H. Baines	221	1,670	6,149	786	1,773	320	44	981	565	11	918	32	21	6,797	2,844	585	8	64	107	172	.288	.346	.463	.809	951	168.9	.352	115	124.5
14	Chet Lemon C. Lemon	215	1,988	6,868	973	1,875	396	61	884	749	151	1,024	58	76	7,872	3,038	672	50	54	46	174	.273	.355	.442	.797	1115	229.1	.356	122	202.2
15	Carlton Fisk C. Fisk	214	1,421	4,896	649	1,259	214	14	762	460	84	798	67	32	5,500	2,143	442	13	47	73	118	.257	.329	.438	.766	703	83	.338	108	51.4
16	Lance Parrish L. Parrish	212	1,146	4,273	577	1,123	201	23	700	334	19	847	22	30	4,674	2,006	436	13	35	37	116	.263	.317	.469	.786	621	95.7	.345	113	73.5
17	Bill Freehan B. Freehan	200	1,774	6,073	706	1,591	241	35	758	626	114	753	24	21	6,899	2,502	476	38	48	67	138	.262	.340	.412	.752	874	152.4	.339	113	96.7
18	Kirk Gibson K. Gibson	195	1,177	4,170	698	1,140	187	45	668	499	43	930	194	64	4,773	2,002	427	18	43	50	45	.273	.354	.480	.834	714	159.9	.364	125	140.8
19	Dick McAuliffe D. McAuliffe	192	1,656	5,898	856	1,471	218	70	671	842	32	932	61	59	6,829	2,405	480	28	29	54	69	.249	.345	.408	.753	878	157.7	.339	113	96.3
20	Bobby Higginson B. Higginson	187	1,362	4,910	736	1,336	270	33	709	649	37	796	91	53	5,660	2,233	490	12	52	36	83	.272	.358	.455	.813	811	102.2	.354	111	84
21	Alan Trammell A. Trammell	185	2,293	8,288	1,231	2,365	412	55	1,003	850	37	874	236	109	9,375	3,442	652	124	76	48	156	.285	.352	.415	.767	1236	166	.343	111	122.3
22	Charlie Gehringer C. Gehringer	184	2,323	8,860	1,775	2,839	574	146	1,427	1,186	50	372	181		10,237	4,257	904	141			27	.320	.404	.480	.884	1797	516.6	.405	124	350
23	Robin Ventura R. Ventura	171	1,254	4,542	658	1,244	219	12	741	668	15	659	15	26	5,310	2,000	402	28	57	86	107	.274	.365	.440	.805	748	115	.353	116	103.6
24	Jermaine Dye J. Dye	164	724	2,669	419	742	150	8	461	251	30	536	23	12	2,970	1,400	322	0	20	14	80	.278	.344	.525	.869	464	102.4	.370	122	80.8
25	Harry Heilmann H. Heilmann	164	1,990	7,297	1,209	2,499	497	145	1,443	792	39	498	111		8,390	3,778	806	262				.342	.410	.518	.927	1566	583.7	.427	145	493.8