Since 2005, Albert Pujols has crushed the most homers, with 543 homers.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Albert Pujols A. Pujols	543	2,451	9,058	1,414	2,597	497	7	1,714	1,069	88	1,125	104	30	10,313	4,737	1,047	0	98	273	351	.287	.364	.523	.887	1659	445.1	.372	135	441.6
2	Miguel Cabrera M. Cabrera	466	2,550	9,439	1,411	2,913	575	13	1,707	1,165	66	1,873	35	17	10,765	4,912	1,054	1	94	230	332	.309	.385	.520	.905	1825	556.8	.384	140	519.6
3	Nelson Cruz N. Cruz	464	2,055	7,501	1,090	2,053	372	15	1,325	738	86	1,916	84	32	8,387	3,847	851	2	60	78	179	.274	.343	.513	.856	1294	313.6	.363	129	286.2
4	Giancarlo Stanton G. Stanton	453	1,726	6,274	943	1,619	313	11	1,169	805	54	2,059	42	15	7,173	3,313	777	0	40	91	158	.258	.345	.528	.874	1145	313.5	.369	136	307.6
5	Edwin Encarnacion E. Encarnacion	424	1,960	7,040	1,099	1,832	370	10	1,261	903	105	1,426	61	14	8,114	3,494	804	0	66	54	185	.260	.350	.496	.846	1233	280.2	.362	125	235.4
6	David Ortiz D. Ortiz	411	1,675	6,133	1,031	1,775	438	11	1,290	1,000	24	1,195	13	7	7,220	3,468	860	1	62	180	180	.289	.388	.565	.953	1304	460.8	.400	146	402.8
7	Mike Trout M. Trout	404	1,648	5,966	1,196	1,754	325	55	1,018	1,067	106	1,662	214	38	7,200	3,401	784	0	61	130	75	.294	.407	.570	.977	1392	555.5	.410	166	556.8
8	Ryan Howard R. Howard	380	1,553	5,668	843	1,464	272	21	1,189	707	58	1,830	12	5	6,488	2,918	673	0	55	154	114	.258	.344	.515	.858	970	210.4	.361	121	173.9
9	Paul Goldschmidt P. Goldschmidt	372	2,074	7,608	1,280	2,190	477	24	1,232	1,086	53	1,979	174	36	8,804	3,831	873	0	57	121	174	.288	.378	.504	.882	1462	430.2	.375	137	385.9
10	Manny Machado M. Machado	369	1,894	7,424	1,082	2,069	396	18	1,144	663	30	1,433	113	41	8,195	3,608	783	14	64	72	224	.279	.338	.486	.824	1193	230.2	.350	123	224.1
11	Aaron Judge A. Judge	368	1,145	4,105	873	1,205	203	7	830	817	40	1,369	65	21	4,995	2,526	578	0	33	104	116	.294	.413	.615	1.028	1050	453.4	.425	178	457.2
12	Freddie Freeman F. Freeman	367	2,179	8,114	1,379	2,431	547	33	1,322	1,070	113	1,763	104	32	9,363	4,145	947	0	66	142	172	.300	.386	.511	.897	1600	506.4	.381	142	474.4
13	Bryce Harper B. Harper	363	1,785	6,435	1,154	1,801	401	24	1,051	1,105	52	1,654	152	52	7,665	3,339	788	13	60	137	139	.280	.387	.519	.905	1322	422.1	.382	141	384.3
14	Joey Votto J. Votto	356	2,056	7,252	1,171	2,135	459	22	1,144	1,365	81	1,640	80	29	8,746	3,706	837	0	48	147	168	.294	.409	.511	.920	1563	539.6	.394	145	472.9
15	Nolan Arenado N. Arenado	353	1,787	6,807	992	1,921	405	34	1,184	577	43	1,094	31	23	7,512	3,453	792	5	80	80	202	.282	.338	.507	.846	1136	252.2	.356	116	148.1
16	Ryan Braun R. Braun	352	1,766	6,622	1,080	1,963	408	49	1,154	586	77	1,363	216	60	7,329	3,525	809	0	44	56	179	.296	.358	.532	.891	1210	352.7	.379	135	310.8
17	Mark Teixeira M. Teixeira	345	1,571	5,862	932	1,572	345	11	1,102	806	87	1,204	21	4	6,815	2,974	701	0	60	74	138	.268	.362	.507	.869	1078	277.4	.372	128	235.8
18	Jose Bautista J. Bautista	344	1,734	5,963	1,016	1,478	309	17	973	1,025	80	1,354	70	31	7,148	2,853	670	22	58	58	169	.248	.362	.478	.841	1081	249.2	.364	127	219.8
19	Adam Dunn A. Dunn	344	1,500	5,155	784	1,201	242	6	895	969	58	1,814	26	11	6,216	2,487	592	1	33	88	76	.233	.358	.482	.841	932	204	.362	121	161.2
20	Curtis Granderson C. Granderson	344	2,048	7,211	1,215	1,794	345	94	937	921	67	1,908	153	50	8,278	3,359	783	30	49	31	63	.249	.337	.466	.803	1146	173.8	.347	115	148.4
21	Evan Longoria E. Longoria	342	1,986	7,306	1,017	1,930	431	26	1,159	730	72	1,696	58	19	8,206	3,439	799	1	97	87	206	.264	.333	.471	.804	1119	163.4	.343	118	170.3
22	Kyle Schwarber K. Schwarber	340	1,291	4,544	800	1,050	175	14	784	764	50	1,527	37	19	5,384	2,273	529	1	25	47	53	.231	.346	.500	.846	837	193.8	.359	127	174.5
23	Carlos Santana C. Santana	335	2,204	7,815	1,107	1,880	404	17	1,136	1,330	43	1,540	65	18	9,254	3,323	756	0	66	66	188	.241	.352	.425	.777	1256	176	.339	114	151.2
24	Robinson Cano R. Cano	335	2,267	8,773	1,262	2,639	572	33	1,306	620	85	1,214	51	38	9,550	4,282	940	10	62	112	286	.301	.351	.488	.839	1411	291.8	.358	124	273.3
25	Andrew McCutchen A. McCutchen	332	2,262	8,350	1,290	2,266	451	50	1,152	1,183	94	1,893	220	90	9,705	3,813	833	3	75	74	147	.271	.365	.457	.822	1441	313.2	.356	125	289.9