Babe Ruth has the most career RBIs in the AL, with 2,202 RBIs.

	NAME	RBI	G	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	2,202	2,475	8,327	2,161	2,860	506	136	708	2,042	43	1,306	123		10,525	5,762	1,350	113				.343	.475	.692	1.167	2713	1,434.9	.514	198	1,367.1
2	Alex Rodriguez A. Rodriguez	2,086	2,784	10,566	2,021	3,115	548	31	696	1,338	176	2,287	329	76	12,207	5,813	1,275	16	111	97	261	.295	.380	.550	.930	2178	690.1	.395	141	629.5
3	Lou Gehrig L. Gehrig	1,995	2,164	8,001	1,888	2,721	534	163	493	1,508	45	790	102		9,660	5,060	1,190	106			2	.340	.447	.632	1.080	2265	1,046.8	.477	173	980
4	Ty Cobb T. Cobb	1,933	3,034	11,434	2,244	4,189	724	295	117	1,249	94	681	897		13,068	5,854	1,136	291				.366	.433	.512	.945	2534	1,093.6	.445	165	975.1
5	Jimmie Foxx J. Foxx	1,863	2,143	7,685	1,696	2,543	438	124	524	1,405	13	1,212	86		9,173	4,801	1,086	70			57	.331	.435	.625	1.060	2087	939.4	.468	162	789
6	Carl Yastrzemski C. Yastrzemski	1,844	3,308	11,988	1,816	3,419	646	59	452	1,845	40	1,393	168	116	13,991	5,539	1,157	13	105	190	323	.285	.379	.462	.841	2155	643.2	.375	130	469.8
7	Ted Williams T. Williams	1,839	2,292	7,706	1,798	2,654	525	71	521	2,021	39	709	24	4	9,791	4,884	1,117	5	20	86	197	.344	.482	.634	1.116	2349	1,219.7	.493	188	1,067
8	Al Simmons A. Simmons	1,784	2,113	8,408	1,468	2,831	522	144	300	591	28	694	88		9,134	4,541	966	107			10	.337	.382	.540	.922	1669	521.7	.413	132	399.9
9	David Ortiz D. Ortiz	1,768	2,408	8,640	1,419	2,472	632	19	541	1,319	38	1,750	17	9	10,091	4,765	1,192	2	92	209	236	.286	.380	.552	.931	1760	559.9	.392	140	484.1
10	Rafael Palmeiro R. Palmeiro	1,740	2,573	9,598	1,547	2,763	525	32	544	1,291	82	1,282	82	35	11,095	4,984	1,101	13	111	165	213	.288	.373	.519	.892	1841	496.5	.382	131	434.6
11	Frank Thomas F. Thomas	1,704	2,322	8,199	1,494	2,468	495	12	521	1,667	87	1,397	32	23	10,074	4,550	1,028	0	121	168	226	.301	.419	.555	.974	1954	721.1	.416	154	692
12	Reggie Jackson R. Jackson	1,702	2,820	9,864	1,551	2,584	463	49	563	1,375	96	2,597	228	115	11,416	4,834	1,075	13	68	164	183	.262	.356	.490	.846	1749	503	.374	139	497.6
13	Cal Ripken Jr. C. Ripken Jr.	1,695	3,001	11,551	1,647	3,184	603	44	431	1,129	66	1,305	36	39	12,883	5,168	1,078	10	127	107	350	.276	.340	.447	.788	1734	219.3	.346	111	175.1
14	Manny Ramirez M. Ramirez	1,675	2,079	7,509	1,414	2,337	494	18	511	1,191	98	1,656	35	31	8,882	4,400	1,023	2	82	175	227	.311	.408	.586	.994	1754	648.7	.418	151	588.3
15	Harold Baines H. Baines	1,628	2,830	9,908	1,299	2,866	488	49	384	1,062	14	1,441	34	34	11,092	4,604	921	9	99	187	298	.289	.356	.465	.820	1599	304.2	.358	118	249.9
16	Goose Goslin G. Goslin	1,612	2,287	8,656	1,482	2,735	500	173	248	949	55	585	176		9,822	4,325	921	162				.316	.387	.500	.887	1695	458.2	.402	127	355.4
17	George Brett G. Brett	1,596	2,707	10,349	1,583	3,154	665	137	317	1,096	33	908	201	97	11,624	5,044	1,119	26	120	229	235	.305	.369	.487	.857	1799	496.2	.374	132	436.3
18	Harmon Killebrew H. Killebrew	1,584	2,435	8,147	1,283	2,086	290	24	573	1,559	48	1,699	19	18	9,831	4,143	887	0	77	160	243	.256	.376	.509	.884	1630	569	.389	142	477.8
19	Al Kaline A. Kaline	1,582	2,834	10,116	1,622	3,007	498	75	399	1,277	55	1,020	137	65	11,597	4,852	972	45	104	131	271	.297	.376	.480	.855	1825	555.2	.378	134	453.6
20	Joe DiMaggio J. DiMaggio	1,537	1,736	6,821	1,390	2,214	389	131	361	790	46	369	30	0	7,671	3,948	881	14			130	.325	.398	.579	.977	1517	604.1	.439	152	528.8
21	Tristram Speaker T. Speaker	1,531	2,789	10,195	1,882	3,514	792	222	117	1,381	103	394	436		11,988	5,101	1,131	309				.345	.428	.500	.928	2264	921	.436	157	812.3
22	Mickey Mantle M. Mantle	1,509	2,401	8,102	1,676	2,415	344	72	536	1,733	13	1,710	153	38	9,909	4,511	952	14	47	126	113	.298	.421	.557	.977	1941	840	.428	170	821.8
23	Jim Rice J. Rice	1,451	2,089	8,225	1,249	2,452	373	79	382	670	64	1,423	58	34	9,058	4,129	834	5	94	77	315	.298	.352	.502	.854	1410	394.2	.375	128	300.2
24	Harry Heilmann H. Heilmann	1,443	1,990	7,297	1,209	2,499	497	145	164	792	39	498	111		8,390	3,778	806	262				.342	.410	.518	.927	1566	583.7	.427	145	493.8
25	Eddie Murray E. Murray	1,442	2,239	8,440	1,255	2,454	421	27	396	1,001	15	1,156	79	29	9,550	4,117	844	2	92	148	227	.291	.363	.488	.851	1469	363.8	.371	130	338.1