who has the highest career batting average against the white sox with at least 200 plate appearances

George Sisler has the best career batting average when making 200+ plate appearances against the White Sox, with an average of .379.

	NAME	AVG	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	OBP	SLG	OPS
1	George Sisler G. Sisler	.379	959	219	883	155	335	44	20	12		46	5	42	41		455	76	25				.413	.515	.929
2	Dale Alexander D. Alexander	.359	384	92	334	53	120	32	7	5	65	41	1	17	3		181	44	8				.431	.542	.973
3	Ty Cobb T. Cobb	.355	1,853	427	1,621	301	575	96	30	11		177	13		108		764	137	42				.422	.471	.894
4	Josh Naylor J. Naylor	.353	215	55	201	36	71	20	0	11	42	13	1	31	5	0	124	31	0	0	1	1	.395	.617	1.012
5	Tom McBride T. McBride	.351	297	78	268	39	94	17	3	1	36	24	0	11	3		120	21	5			8	.404	.448	.852
6	Lou Gehrig L. Gehrig	.350	1,381	303	1,158	280	405	84	22	77	300	198	4	84	17		764	183	21				.446	.660	1.106
7	Dick Porter D. Porter	.348	359	82	328	71	114	27	6	2	40	27	0	13	3		159	35	4				.397	.485	.882
8	Harry Heilmann H. Heilmann	.347	1,178	277	1,037	162	360	74	18	20		102	3	61	14		530	112	36				.407	.511	.918
9	Tristram Speaker T. Speaker	.346	1,712	405	1,477	240	511	119	32	11		189	10		46		727	162	36				.424	.492	.916
10	Ryan Garko R. Garko	.346	204	53	185	29	64	6	0	9	37	15	2	29	0	0	97	15	0	2	0	3	.397	.524	.921
11	Steve Kemp S. Kemp	.346	241	58	217	34	75	10	2	6	44	22	0	25	3	1	107	18	1	1	1	3	.404	.493	.897
12	Mule Haas M. Haas	.343	426	95	379	67	130	19	4	6	49	23	1	22	0		175	29	23				.382	.462	.844
13	Heinie Manush H. Manush	.342	1,176	281	1,076	198	368	67	30	17	182	60	9	40	16		546	114	31				.382	.507	.889
14	Joe Jackson J. Jackson	.340	429	104	376	59	128	21	8	0		42	4		22		165	29	7				.412	.439	.851
15	Babe Ruth B. Ruth	.340	1,491	354	1,188	303	404	74	18	98	331	287	4	173	16		808	190	12				.470	.680	1.150
16	Roy Johnson R. Johnson	.339	646	149	578	113	196	40	8	7	87	62	2	39	30		273	55	4				.405	.472	.877
17	Bernie Williams B. Williams	.339	526	123	466	94	158	30	4	20	90	54	2	69	10	2	256	54	1	3	1	9	.408	.549	.957
18	Nap Lajoie N. Lajoie	.339	1,164	283	1,056	151	358	71	11	6		69	10		43		469	88	29				.385	.444	.829
19	Johnny Bassler J. Bassler	.337	424	121	347	43	117	21	2	0	58	61	2	4	2		142	23	14				.439	.409	.848
20	Al Simmons A. Simmons	.337	1,101	253	1,028	188	346	53	21	37	243	60	2	57	6		552	111	11			4	.374	.537	.911
21	Barney McCosky B. McCosky	.336	672	160	586	104	197	27	9	1	51	69	2	32	11	0	245	37	15			7	.408	.418	.826
22	Johnny Hodapp J. Hodapp	.335	372	93	346	46	116	21	3	2	55	19	1	21	1		149	26	6				.372	.431	.802
23	Bob Fothergill B. Fothergill	.335	307	104	278	39	93	16	3	3	44	20	1	19	5		124	22	8				.381	.446	.827
24	Darin Erstad D. Erstad	.334	339	75	311	55	104	22	0	8	47	19	2	42	11	4	150	30	2	5	2	4	.371	.482	.853
25	Delmon Young D. Young	.334	365	90	335	50	112	22	2	13	57	19	8	69	3	2	177	37	0	3	4	9	.381	.528	.909