who has the highest career slug against the white sox with at least 200 plate appearances

Babe Ruth has the best career slugging percentage when making 200+ plate appearances against the White Sox, with a slugging percentage of .680.

	NAME	SLG	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	OPS
1	Babe Ruth B. Ruth	.680	1,491	354	1,188	303	404	74	18	98	331	287	4	173	16		808	190	12				.340	.470	1.150
2	Lou Gehrig L. Gehrig	.660	1,381	303	1,158	280	405	84	22	77	300	198	4	84	17		764	183	21				.350	.446	1.106
3	Jimmie Foxx J. Foxx	.628	1,320	309	1,090	240	362	57	20	75	267	220	2	159	10		684	152	8			9	.332	.445	1.073
4	Jim Thome J. Thome	.626	588	144	486	95	146	25	2	43	117	94	2	145	3	1	304	70	0	6	10	8	.300	.412	1.037
5	Josh Naylor J. Naylor	.617	215	55	201	36	71	20	0	11	42	13	1	31	5	0	124	31	0	0	1	1	.353	.395	1.012
6	Joe DiMaggio J. DiMaggio	.609	1,037	236	935	192	303	42	25	58	203	96	5	44	5	0	569	125	1			19	.324	.390	.999
7	Byron Buxton B. Buxton	.593	377	99	339	69	96	30	3	23	56	29	5	100	11	3	201	56	1	3	2	2	.283	.346	.939
8	Richie Sexson R. Sexson	.592	203	49	184	27	52	12	0	15	36	17	1	38	0	1	109	27	0	1	2	6	.283	.345	.937
9	Danny Tartabull D. Tartabull	.588	397	97	340	58	102	23	3	23	71	53	1	86	1	2	200	49	0	3	1	11	.300	.393	.981
10	Josh Donaldson J. Donaldson	.587	313	75	259	49	72	11	0	23	59	48	1	52	0	0	152	34	0	5	0	10	.278	.387	.973
11	Mike Trout M. Trout	.585	318	75	248	57	74	12	1	19	50	61	7	84	10	4	145	32	0	2	12	2	.298	.447	1.031
12	Jason Kubel J. Kubel	.579	312	84	285	51	78	15	3	22	77	20	0	69	1	0	165	40	1	6	2	3	.274	.315	.894
13	Ted Williams T. Williams	.574	1,388	330	1,125	226	364	63	12	65	244	256	4	101	2	0	646	140	0	3	19	30	.324	.450	1.024
14	Darrell Porter D. Porter	.573	348	97	293	50	96	10	7	16	56	47	1	46	0	4	168	33	2	5	2	4	.328	.416	.990
15	Sammy Sosa S. Sosa	.571	227	53	198	32	56	15	0	14	49	22	1	56	2	2	113	29	0	6	2	3	.283	.348	.919
16	Cecil Fielder C. Fielder	.570	479	118	409	68	111	20	0	34	97	62	4	104	0	2	233	54	0	4	3	12	.271	.370	.939
17	Troy Glaus T. Glaus	.564	282	66	243	51	64	10	0	21	49	33	2	50	4	3	137	31	0	4	0	4	.263	.351	.915
18	Bobby Abreu B. Abreu	.563	229	54	192	40	59	13	0	12	48	34	0	45	10	2	108	25	0	3	1	4	.307	.406	.969
19	Jermaine Dye J. Dye	.560	248	57	225	43	67	12	1	15	44	19	2	29	0	2	126	28	0	2	3	9	.298	.355	.915
20	Hank Greenberg H. Greenberg	.556	780	181	649	129	187	42	12	36	144	120	5	103	12		361	90	6			1	.288	.403	.959
21	Manny Ramirez M. Ramirez	.556	510	120	423	83	136	24	0	25	91	76	6	89	4	2	235	49	0	5	11	13	.322	.427	.983
22	Mickey Mantle M. Mantle	.552	1,333	322	1,121	210	329	54	10	72	192	206	0	231	23	6	619	136	3	3	23	22	.293	.402	.954
23	Mark McGwire M. McGwire	.551	420	105	354	61	89	10	0	32	75	55	6	82	0	1	195	42	0	5	7	7	.251	.357	.908
24	Bob Allison B. Allison	.550	732	189	633	107	176	27	8	43	107	91	1	103	15	8	348	78	4	3	11	11	.278	.368	.918
25	Bernie Williams B. Williams	.549	526	123	466	94	158	30	4	20	90	54	2	69	10	2	256	54	1	3	1	9	.339	.408	.957