| NAME | SO | G | H | HR | BB | HBP | IBB | K/BB | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R. Johnson | 399 | 314 | 223 | 22 | 110 | 14 | 0 | 3.63 | |
| 2 | R. Clemens | 387 | 368 | 289 | 18 | 133 | 20 | 2 | 2.91 | |
| 3 | N. Ryan | 350 | 333 | 224 | 17 | 191 | 8 | 1 | 1.83 | |
| 4 | J. Verlander | 295 | 278 | 217 | 39 | 97 | 10 | 0 | 3.04 | |
| 5 | M. Mussina | 288 | 275 | 233 | 28 | 62 | 5 | 0 | 4.65 | |
| 6 | M. Scherzer | 286 | 232 | 201 | 34 | 64 | 10 | 0 | 4.47 | |
| 7 | G. Maddux | 279 | 369 | 367 | 29 | 92 | 13 | 9 | 3.03 | |
| 8 | CC Sabathia | 278 | 275 | 211 | 27 | 83 | 8 | 0 | 3.35 | |
| 9 | C. Kershaw | 258 | 228 | 175 | 19 | 61 | 8 | 1 | 4.23 | |
| 10 | F. Tanana | 258 | 314 | 300 | 23 | 100 | 5 | 12 | 2.58 | |
| 11 | Z. Greinke | 255 | 276 | 269 | 20 | 55 | 5 | 0 | 4.64 | |
| 12 | B. Blyleven | 244 | 282 | 264 | 16 | 76 | 12 | 2 | 3.21 | |
| 13 | B. Colon | 240 | 276 | 262 | 23 | 78 | 10 | 2 | 3.08 | |
| 14 | D. Cone | 233 | 204 | 160 | 18 | 72 | 6 | 0 | 3.24 | |
| 15 | A.J. Burnett | 231 | 208 | 153 | 13 | 76 | 9 | 0 | 3.04 | |
| 16 | C. Schilling | 230 | 222 | 198 | 23 | 57 | 4 | 3 | 4.04 | |
| 17 | C. Morton | 226 | 210 | 166 | 18 | 81 | 25 | 1 | 2.79 | |
| 18 | A. Pettitte | 223 | 258 | 238 | 26 | 69 | 7 | 1 | 3.23 | |
| 19 | J. Lester | 221 | 226 | 227 | 35 | 86 | 7 | 0 | 2.57 | |
| 20 | C. Sale | 219 | 151 | 128 | 17 | 43 | 12 | 0 | 5.09 | |
| 21 | P. Martinez | 219 | 193 | 153 | 13 | 44 | 9 | 0 | 4.98 | |
| 22 | J. Smoltz | 217 | 238 | 206 | 24 | 86 | 2 | 7 | 2.52 | |
| 23 | C. Hamels | 214 | 205 | 168 | 26 | 63 | 10 | 2 | 3.40 | |
| 24 | J. Vazquez | 211 | 216 | 210 | 32 | 47 | 8 | 1 | 4.49 | |
| 25 | J. Lackey | 208 | 222 | 200 | 23 | 71 | 10 | 0 | 2.93 | |