Since 2010, the Chicago Cubs have the worst record by a team versus the Yankees, with a record of 5-14.

	TEAM	REC	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	5-14	.263	19	5	14	664	50	127	23	9	11	48	60	6	183	9	7	741	201	43	7	4	6	10	.191	.263	.303	.566
2	Giants	5-13	.278	18	5	13	595	56	122	30	1	14	53	61	6	177	6	2	664	196	45	0	2	0	9	.205	.285	.329	.614
3	Twins	28-66	.298	94	28	66	3,214	389	785	160	10	120	372	245	27	806	32	17	3,511	1,325	290	8	17	7	59	.244	.302	.412	.714
4	Royals	32-69	.317	101	32	69	3,419	385	826	157	15	105	369	266	33	791	82	31	3,758	1,328	277	14	26	13	59	.242	.300	.388	.689
5	Mariners	37-65	.363	102	37	65	3,392	328	740	133	8	97	318	276	43	950	45	27	3,747	1,180	238	18	18	12	63	.218	.284	.348	.632
6	Guardians	40-61	.396	101	40	61	3,407	409	792	150	14	104	383	332	33	896	73	20	3,812	1,282	268	14	26	8	63	.232	.305	.376	.681
7	White Sox	37-55	.402	92	37	55	3,126	368	786	153	8	99	353	235	27	777	49	22	3,410	1,252	260	8	14	6	67	.251	.308	.401	.709
8	Angels	40-59	.404	99	40	59	3,331	412	820	148	11	118	397	316	39	809	59	21	3,723	1,344	277	17	20	17	66	.246	.317	.403	.721
9	Reds	9-13	.409	22	9	13	733	88	154	26	2	24	86	58	12	212	12	8	811	256	52	4	4	0	12	.210	.278	.349	.627
10	Pirates	8-11	.421	19	8	11	615	78	133	25	4	25	75	61	6	182	8	4	694	241	54	2	10	2	9	.216	.289	.392	.681
11	Astros	32-44	.421	76	32	44	2,566	314	618	128	8	96	306	207	28	660	53	13	2,818	1,050	232	5	12	5	56	.241	.303	.409	.712
12	Braves	11-15	.423	26	11	15	871	103	211	40	2	33	100	84	8	237	9	1	970	354	75	4	3	3	14	.242	.314	.406	.720
13	Orioles	112-152	.424	264	112	152	9,054	1,114	2,233	461	21	323	1,070	715	95	2,317	114	34	9,959	3,705	805	35	60	31	165	.247	.307	.409	.716
14	Brewers	9-12	.429	21	9	12	751	103	195	39	2	23	98	70	12	209	19	3	842	307	64	2	7	1	10	.260	.330	.409	.739
15	Tigers	42-56	.429	98	42	56	3,301	381	826	152	17	94	368	258	28	897	35	12	3,633	1,294	263	11	35	12	68	.250	.307	.392	.699
16	Phillies	10-13	.435	23	10	13	790	111	194	36	5	22	105	86	14	202	12	1	898	306	63	4	4	7	9	.246	.329	.387	.716
17	Athletics	46-58	.442	104	46	58	3,518	396	812	152	15	117	384	311	36	883	50	16	3,900	1,345	284	13	22	9	60	.231	.298	.382	.680
18	Padres	8-10	.444	18	8	10	581	62	127	22	2	16	59	63	9	152	16	3	659	201	40	1	5	2	9	.219	.302	.346	.648
19	Rangers	45-56	.446	101	45	56	3,382	446	817	165	10	104	421	315	43	845	75	27	3,778	1,314	279	21	17	14	62	.242	.313	.389	.701
20	Marlins	9-11	.450	20	9	11	672	78	152	17	5	14	74	55	8	185	8	3	745	221	36	6	4	2	15	.226	.291	.329	.620
21	Rockies	10-12	.455	22	10	12	748	104	186	43	3	31	99	66	5	213	17	3	828	328	77	4	5	3	12	.249	.312	.439	.750
22	Blue Jays	123-141	.466	264	123	141	8,841	1,108	2,153	459	16	317	1,058	822	94	2,216	132	39	9,849	3,595	792	35	57	24	170	.244	.313	.407	.719
23	Red Sox	125-142	.468	267	125	142	9,236	1,265	2,378	529	31	322	1,209	849	97	2,258	147	36	10,285	3,935	882	24	79	50	197	.257	.324	.426	.750
24	Nationals	11-12	.478	23	11	12	764	83	174	31	1	35	78	60	7	191	14	4	840	312	67	6	3	3	15	.228	.289	.408	.697
25	Mets	37-40	.481	77	37	40	2,572	342	633	140	5	95	329	226	35	660	33	17	2,859	1,068	240	10	16	9	46	.246	.314	.415	.729