Between the 1876 and 1947 seasons, Charlie Root pitched in the most games for the Cubs, with 605 games.

Interpreted as:

Most regular-season games cubs pitcher 1876 to 1947

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Charlie Root C. Root	605	201	156	.563	339	3.55	1,432	177	21	42	3137.1	3,184	1,236	1,422	185	871	73	171	13,266	21	4.11	2.50	1.64	0.53	10.8	6.6	1.29	.280	4.08	90	3.78	94	9.13	85.7
2	Guy Bush G. Bush	428	152	101	.601	252	3.81	712	127	14	27	2201.2	2,354	933	1,101	121	734	36	110	9,506	44	2.91	3.00	0.97	0.49	7.5	7.7	1.40	.283	4.50	93	4.18	102	9.62	-24.3
3	William Hutchinson W. Hutchinson	368	180	158	.533	339	3.56	1,225	317	21	4	3022.1	3,055	1,196	1,861	99	1,109	84	28	13,196	120	3.65	3.30	1.10	0.29	9.3	8.4	1.38	.277	5.54	86	3.74	89	9.10	161
4	Bill Lee B. Lee	364	139	123	.531	297	3.51	874	153	25	9	2271.1	2,317	885	1,013	111	704	19	37	9,631	45	3.46	2.79	1.24	0.44	9.1	7.3	1.33	.278	4.01	93	3.74	95	9.18	44.5
5	Mordecai Brown M. Brown	346	188	86	.686	241	1.80	1,043	206	48	39	2329.0	1,879	465	679	19	445	44	98	8,967	41	4.03	1.72	2.34	0.07	11.6	5.0	1.00	.251	2.62	64	2.21	78	7.26	159.6
6	Hippo Vaughn H. Vaughn	305	151	105	.590	270	2.33	1,138	177	35	4	2216.1	1,971	575	789	35	621	63	31	9,097	41	4.62	2.52	1.83	0.14	12.5	6.8	1.17	.267	3.20	79	2.56	86	8.00	96.3
7	Claude Passeau C. Passeau	292	124	94	.569	234	2.96	754	143	22	15	1914.2	1,919	629	751	73	474	21	44	8,063	17	3.54	2.23	1.59	0.34	9.4	5.9	1.25	.274	3.53	83	3.09	86	9.02	111
8	Ed Reulbach E. Reulbach	281	136	65	.677	216	2.24	799	149	31	9	1864.2	1,459	464	606	21	650	85	54	7,405	29	3.86	3.14	1.23	0.10	10.8	8.8	1.13	.246	2.92	79	2.87	99	7.04	0
9	Larry French L. French	272	95	84	.531	185	3.54	642	87	21	8	1486.0	1,586	585	659	89	382	17	50	6,331	15	3.89	2.31	1.68	0.54	10.1	6.0	1.32	.288	3.99	92	3.71	93	9.61	48.9
10	Larry Corcoran L. Corcoran	270	175	85	.673	262	2.26	1,086	252	22	2	2338.1	2,084	588	1,181	65	462		8	9,740	111	4.18	1.78	2.35	0.25	11.1	4.7	1.09		4.55	77	2.94	96	8.02	51.8
11	Pat Malone P. Malone	265	115	79	.593	199	3.57	878	106	15	9	1632.0	1,628	648	766	87	577	36	45	6,998	40	4.84	3.18	1.52	0.48	12.5	8.2	1.35	.284	4.22	88	3.85	93	8.98	59.1
12	Clark Griffith C. Griffith	265	152	96	.613	252	3.40	573	240	9	1	2188.2	2,445	826	1,249	42	517	116	13	9,360	36	2.36	2.13	1.11	0.17	6.1	5.5	1.35	.296	5.14	77	3.82	88	10.05	130.9
13	Lon Warneke L. Warneke	262	109	72	.602	190	2.84	706	122	17	12	1624.2	1,549	512	613	71	413	17	48	6,708	33	3.91	2.29	1.71	0.39	10.5	6.2	1.21	.269	3.40	75	3.46	90	8.58	68.5
14	Sheriff Blake S. Blake	255	81	92	.468	183	3.95	551	78	11	7	1455.1	1,555	639	757	60	661	26	42	6,378	27	3.41	4.09	0.83	0.37	8.6	10.4	1.52	.294	4.68	94	4.28	102	9.62	-13.2
15	Grover Alexander G. Alexander	242	128	83	.607	224	2.84	614	158	24	10	1884.1	1,919	595	717	70	268	10	15	7,647	13	2.93	1.28	2.29	0.33	8.0	3.5	1.16	.277	3.42	75	3.17	84	9.17	120.9
16	Jack Taylor J. Taylor	216	109	90	.548	197	2.65	430	189	14	3	1810.0	1,772	532	857	23	370	63	19	7,355	26	2.14	1.84	1.16	0.11	5.8	5.0	1.18	.270	4.26	83	3.15	98	8.81	8.7
17	Percy Jones P. Jones	207	46	41	.529	90	4.22	309	38	7	8	818.2	892	384	456	35	399	33	73	3,664	18	3.40	4.39	0.77	0.38	8.4	10.9	1.58	.297	5.01	106	4.38	109	9.81	-34.3
18	John Clarkson J. Clarkson	199	137	57	.706	197	2.39	960	186	15	0	1730.2	1,523	460	850	69	300	8	2	7,062	63	4.99	1.56	3.20	0.36	13.6	4.2	1.05	.254	4.42	67	3.03	82	7.92	155.6
19	Hank Wyse H. Wyse	198	69	54	.561	133	3.03	321	63	11	8	1063.0	1,105	358	432	50	268	15	38	4,452	9	2.72	2.27	1.20	0.42	7.2	6.0	1.29	.278	3.66	85	3.29	93	9.36	25.5
20	Paul Erickson P. Erickson	198	35	48	.422	84	3.81	422	27	5	6	790.1	748	335	378	40	400	19	56	3,487	18	4.81	4.56	1.06	0.46	12.1	11.5	1.45	.272	4.30	107	3.69	103	8.52	-11.9
21	Jimmy Lavender J. Lavender	196	57	68	.456	128	3.03	495	58	10	11	1078.0	978	363	486	33	403	53	41	4,522	25	4.13	3.36	1.23	0.28	10.9	8.9	1.28	.267	4.06	102	3.28	108	8.17	-29.3
22	Carl Lundgren C. Lundgren	179	91	55	.623	149	2.42	535	125	19	6	1322.0	1,129	355	496	16	476	35	28	5,320	26	3.64	3.24	1.12	0.11	10.1	8.9	1.21	.261	3.38	90	2.94	106	7.69	-23.7
23	Fred Goldsmith F. Goldsmith	177	107	63	.629	174	2.78	391	164	16	1	1516.2	1,595	468	834	38	168		2	6,382	54	2.32	1.00	2.33	0.23	6.1	2.6	1.16		4.95	92	3.04	100	9.46	13.1
24	Larry Cheney L. Cheney	174	76	51	.598	132	2.74	512	80	14	16	1061.0	900	323	444	22	407	29	37	4,418	71	4.34	3.45	1.26	0.19	11.6	9.2	1.23	.255	3.77	90	3.13	100	7.63	1.2
25	Tony Kaufmann T. Kaufmann	172	63	57	.525	116	3.89	324	70	9	10	999.2	1,065	432	510	73	333	37	40	4,311	12	2.92	3.00	0.97	0.66	7.5	7.7	1.40	.280	4.59	97	4.42	110	9.59	-43.7