Between the 1876 and 1952 seasons, the Chicago Cubs had the most wins by a team, with 5,895 wins.

Interpreted as:

Most games won in the regular season MLB team 1876 to 1952

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	GIDP	AVG	OBP	SLG	OPS
1	Cubs	5,895	4,853	.548	10,884	374,066	53,317	100,729	16,136	4,775	4,287	41,764	32,159	2,320	31,588	10,037	70	417,012	139,276	25,198	8,467	1,618	.269	.331	.372	.703
2	Giants	5,684	4,511	.558	10,351	354,725	50,936	96,536	14,076	4,459	4,943	43,439	30,562	2,763	28,792	10,444	65	394,812	134,359	23,478	6,762	1,707	.272	.335	.379	.713
3	Pirates	5,349	4,964	.519	10,438	358,845	49,020	96,361	14,305	5,904	3,148	41,311	30,270	2,383	28,326	9,145	68	399,427	131,918	23,357	7,806	1,658	.269	.330	.368	.697
4	Dodgers	5,152	4,983	.508	10,266	351,414	47,841	93,310	14,307	4,699	3,560	41,015	30,757	2,313	30,774	9,657	119	391,969	127,695	22,566	7,409	1,605	.266	.329	.363	.692
5	Reds	5,132	5,211	.496	10,471	357,082	47,022	94,149	14,002	5,240	3,023	39,133	28,755	2,345	28,306	10,133	82	396,349	127,700	22,265	7,999	1,583	.264	.323	.358	.681
6	Braves	5,118	5,598	.478	10,854	373,968	48,766	97,880	14,675	4,197	3,424	38,635	30,184	2,335	30,412	8,324	68	414,334	131,221	22,296	7,847	1,633	.262	.321	.351	.672
7	Phillies	4,586	5,589	.451	10,279	354,049	46,874	94,386	15,414	3,876	4,034	40,041	29,411	2,334	31,519	8,199	69	393,336	129,654	23,324	7,542	1,672	.267	.327	.366	.693
8	Cardinals	4,530	4,596	.496	9,240	316,820	41,928	85,462	13,519	4,304	3,591	37,055	27,250	2,220	30,527	7,099	62	353,721	118,362	21,414	7,431	1,528	.270	.332	.374	.705
9	Yankees	4,344	3,234	.573	7,650	259,974	38,077	70,283	11,062	3,431	4,763	34,346	27,749	1,830	28,082	5,528	81	296,029	102,496	19,256	6,476	1,650	.270	.345	.394	.739
10	Indians	4,127	3,751	.524	7,960	271,134	36,241	73,728	13,243	3,503	2,973	32,506	24,811	1,688	27,545	5,281	74	305,337	102,896	19,719	7,704	1,670	.272	.337	.380	.716
11	Tigers	4,103	3,779	.521	7,963	271,305	37,761	74,042	12,255	3,649	3,050	33,486	27,566	1,567	26,232	6,068	72	308,137	102,745	18,954	7,699	1,900	.273	.343	.379	.722
12	Red Sox	3,959	3,899	.504	7,935	269,184	35,424	71,586	12,315	3,353	2,922	31,761	26,120	1,671	27,021	4,836	68	304,473	99,373	18,590	7,498	1,872	.266	.335	.369	.704
13	White Sox	3,880	3,972	.494	7,936	267,488	33,706	69,961	11,000	3,192	1,893	29,753	25,591	1,803	25,647	6,737	108	303,162	93,024	16,085	8,280	1,732	.262	.330	.348	.678
14	Athletics	3,776	4,050	.482	7,900	268,185	35,324	71,583	11,992	3,228	3,292	31,586	25,249	1,642	27,870	4,930	79	302,315	99,907	18,512	7,239	1,873	.267	.334	.373	.706
15	Senators	3,717	4,140	.473	7,954	270,490	34,042	71,447	11,354	3,683	1,902	30,258	25,155	1,931	26,510	6,377	75	304,380	95,873	16,939	6,804	1,663	.264	.331	.354	.686
16	Browns	3,408	4,454	.433	7,960	269,501	33,628	70,443	11,675	3,092	2,928	30,006	25,231	1,488	29,792	5,064	72	303,248	97,086	17,695	7,028	1,670	.261	.328	.360	.688
17	Colonels	993	1,320	.429	2,355	82,256	12,464	21,505	2,816	1,292	436	8,508	6,080	757	3,638	3,474		89,787	28,213	4,544	609		.261	.319	.343	.662
18	Spiders	827	938	.469	1,802	63,232	10,057	17,006	2,308	961	292	8,238	5,871	580	3,144	2,800		70,233	22,112	3,561	550		.269	.337	.350	.686
19	Browns	781	432	.644	1,233	43,777	7,933	11,555	1,658	602	304	4,657	3,473	353	436	2,307		47,743	15,329	2,564			.264	.325	.350	.675
20	Orioles	730	530	.579	1,294	45,361	8,530	13,521	1,814	865	218	6,940	4,345	992	2,952	2,993		51,317	17,719	2,897	619		.298	.372	.391	.763
21	Athletics	633	564	.529	1,219	43,556	7,481	11,208	1,782	741	284	4,168	3,158	351	548	1,900		47,191	15,324	2,807			.257	.315	.352	.666
22	Senators	454	788	.366	1,265	43,645	6,912	11,886	1,615	787	357	5,764	4,269	575	3,492	1,975		48,963	16,146	2,759	474		.272	.345	.370	.715
23	Grays	438	278	.612	725	26,572	4,037	6,764	1,084	341	98	292	1,192					27,764	8,824	1,523			.255		.332
24	Wolverines	426	437	.494	880	31,647	4,849	8,116	1,241	537	264	2,412	1,880	84		654		33,611	11,223	2,042			.256	.300	.355	.655
25	Orioles	403	519	.437	944	32,654	4,964	7,699	1,083	504	136	2,635	2,289	208		1,451		35,293	10,198	1,723			.236	.293	.312	.605