Babe Ruth has the most career RBIs per plate appearance when making 8,000+ plate appearances, with 0.21.

	NAME	RBI/PA	PA	RBI	G	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	0.21	10,617	2,214	2,503	8,399	2,174	2,873	506	136	714	2,062	43	1,330	123		5,793	1,356	113				.342	.474	.690	1.164	2727	1,436.8	.513	197	1,369.6
2	Lou Gehrig L. Gehrig	0.21	9,660	1,995	2,164	8,001	1,888	2,721	534	163	493	1,508	45	790	102		5,060	1,190	106			2	.340	.447	.632	1.080	2265	1,046.8	.477	173	980
3	Jimmie Foxx J. Foxx	0.2	9,670	1,922	2,317	8,134	1,751	2,646	458	125	534	1,452	13	1,311	87		4,956	1,117	71			69	.325	.428	.609	1.038	2135	934.1	.460	158	780.8
4	Al Simmons A. Simmons	0.19	9,515	1,828	2,215	8,759	1,507	2,927	539	149	307	615	30	737	88		4,685	995	111			23	.334	.380	.535	.915	1714	519.5	.410	130	400.1
5	Ted Williams T. Williams	0.19	9,791	1,839	2,292	7,706	1,798	2,654	525	71	521	2,021	39	709	24	4	4,884	1,117	5	20	86	197	.344	.482	.634	1.116	2349	1,219.7	.493	188	1,067
6	Manny Ramirez M. Ramirez	0.19	9,774	1,831	2,302	8,244	1,544	2,574	547	20	555	1,329	109	1,813	38	33	4,826	1,122	2	90	216	243	.312	.411	.585	.996	1931	719.5	.418	153	658.7
7	David Ortiz D. Ortiz	0.18	10,091	1,768	2,408	8,640	1,419	2,472	632	19	541	1,319	38	1,750	17	9	4,765	1,192	2	92	209	236	.286	.380	.552	.931	1760	559.9	.392	140	484.1
8	Carlos Delgado C. Delgado	0.17	8,657	1,512	2,035	7,283	1,241	2,038	483	18	473	1,109	172	1,745	14	8	3,976	974	0	93	186	152	.280	.383	.546	.929	1513	435.7	.391	135	394
9	Ed Delahanty E. Delahanty	0.17	8,400	1,466	1,837	7,511	1,600	2,597	522	186	101	741	94	366	455		3,794	809	54				.346	.411	.505	.916	1836	616.8	.428	144	559.3
10	Jose Canseco J. Canseco	0.17	8,129	1,407	1,887	7,057	1,186	1,877	340	14	462	906	84	1,942	200	88	3,631	816	1	81	63	178	.266	.353	.515	.867	1293	321.2	.375	130	300.8
11	Harry Heilmann H. Heilmann	0.17	8,960	1,540	2,147	7,787	1,291	2,660	542	151	183	856	40	550	113		4,053	876	277				.342	.410	.520	.930	1682	619.2	.427	144	524
12	Yogi Berra Y. Berra	0.17	8,364	1,430	2,120	7,555	1,175	2,150	321	49	358	704	52	414	30	19	3,643	728	9	44	49	146	.285	.348	.482	.830	1233	265.6	.370	124	245.8
13	Alex Rodriguez A. Rodriguez	0.17	12,207	2,086	2,784	10,566	2,021	3,115	548	31	696	1,338	176	2,287	329	76	5,813	1,275	16	111	97	261	.295	.380	.550	.930	2178	690.1	.395	141	629.5
14	Willie Stargell W. Stargell	0.17	9,026	1,540	2,360	7,927	1,194	2,232	423	55	475	937	78	1,936	17	16	4,190	953	9	75	227	143	.282	.360	.529	.889	1471	511.5	.387	145	459.3
15	Jim Bottomley J. Bottomley	0.17	8,355	1,422	1,991	7,471	1,177	2,313	465	151	219	664	43	591	58		3,737	835	177				.310	.369	.500	.869	1377	325.4	.393	124	259.7
16	Albert Pujols A. Pujols	0.17	13,041	2,218	3,080	11,421	1,914	3,384	686	16	703	1,373	123	1,404	117	43	6,211	1,405	1	123	316	426	.296	.374	.544	.918	2233	685	.385	141	673
17	Joe Medwick J. Medwick	0.17	8,142	1,383	1,984	7,635	1,198	2,471	540	113	205	437	26	551	42		3,852	858	44			112	.324	.362	.505	.867	1336	368.3	.393	133	329
18	Frank Thomas F. Thomas	0.17	10,074	1,704	2,322	8,199	1,494	2,468	495	12	521	1,667	87	1,397	32	23	4,550	1,028	0	121	168	226	.301	.419	.555	.974	1954	721.1	.416	154	692
19	Sammy Sosa S. Sosa	0.17	9,896	1,667	2,354	8,813	1,475	2,408	379	45	609	929	59	2,306	234	107	4,704	1,033	17	78	154	202	.273	.344	.534	.878	1559	345.1	.370	124	307.3
20	Rogers Hornsby R. Hornsby	0.17	9,475	1,584	2,259	8,173	1,579	2,930	541	169	301	1,038	48	679	135		4,712	1,011	216				.358	.434	.577	1.010	2018	899	.459	173	863.2
21	Vladimir Guerrero V. Guerrero	0.17	9,059	1,496	2,147	8,155	1,328	2,590	477	46	449	737	103	985	181	94	4,506	972	0	64	250	277	.318	.379	.553	.931	1575	464.6	.390	136	419
22	Hank Aaron H. Aaron	0.16	13,940	2,297	3,298	12,364	2,174	3,771	624	98	755	1,402	32	1,383	240	73	6,856	1,477	21	121	293	328	.305	.374	.555	.928	2453	936.4	.403	153	858.5
23	Jim Thome J. Thome	0.16	10,313	1,699	2,543	8,422	1,583	2,328	451	26	612	1,747	69	2,548	19	20	4,667	1,089	1	74	173	165	.276	.402	.554	.956	1925	653.9	.406	145	589.5
24	Goose Goslin G. Goslin	0.16	9,822	1,612	2,287	8,656	1,482	2,735	500	173	248	949	55	585	176		4,325	921	162				.316	.387	.500	.887	1695	458.2	.402	127	355.4
25	Mel Ott M. Ott	0.16	11,337	1,860	2,730	9,456	1,859	2,876	488	72	511	1,708	64	896	89		5,041	1,071	109			38	.304	.414	.533	.947	2204	826.4	.430	156	794.2