Wilmer Difo had the highest ERA with 2.0+ innings pitched in a season in 2021, with an ERA of 36.00.
| NAME | ERA | IP | SEASON | TM | G | W | L | W% | GS | SO | CG | SHO | SV | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | W. Difo | 36.00 | 2.0 | 2021 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9 | 8 | 8 | 1 | 3 | 0 | 2 | 0 | 18 | 0 | 4.50 | 13.50 | 0.33 | 4.50 | 5.6 | 16.7 | 6.00 | .615 | 36.00 | 850 | 13.16 | 310 | 40.50 | -2 | ||
| 2 | | J. Topa | 29.70 | 3.1 | 2021 | 4 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 12 | 11 | 11 | 2 | 1 | 0 | 0 | 1 | 23 | 0 | 2.70 | 2.70 | 1.00 | 5.40 | 4.3 | 4.3 | 3.90 | .526 | 29.70 | 708 | 11.26 | 263 | 32.40 | -2.6 | ||
| 3 | | F. MejÃa | 27.00 | 2.0 | 2021 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 6 | 6 | 1 | 0 | 2 | 2 | 0 | 14 | 0 | 0.00 | 0.00 | 4.50 | 0.0 | 0.0 | 3.00 | .455 | 27.00 | 658 | 12.66 | 308 | 27.00 | -2 | |||
| 4 | | E. Peguero | 27.00 | 2.1 | 2021 | 3 | 0 | 1 | .000 | 0 | 0 | 0 | 0 | 0 | 7 | 7 | 7 | 0 | 3 | 1 | 0 | 0 | 17 | 0 | 0.00 | 11.57 | 0.00 | 0.00 | 0.0 | 17.6 | 4.29 | .538 | 27.00 | 613 | 8.31 | 190 | 27.00 | -1 | |
| 5 | | K. Crawford | 22.50 | 2.0 | 2021 | 1 | 0 | 1 | .000 | 1 | 2 | 0 | 0 | 0 | 5 | 5 | 5 | 1 | 2 | 0 | 0 | 0 | 13 | 0 | 9.00 | 9.00 | 1.00 | 4.50 | 15.4 | 15.4 | 3.50 | .500 | 22.50 | 491 | 10.66 | 247 | 22.50 | -1.4 | |
| 6 | | G. Santos | 22.50 | 2.0 | 2021 | 3 | 0 | 2 | .000 | 0 | 3 | 0 | 0 | 0 | 5 | 5 | 6 | 3 | 2 | 0 | 1 | 0 | 13 | 0 | 13.50 | 9.00 | 1.50 | 13.50 | 23.1 | 15.4 | 3.50 | .400 | 27.00 | 559 | 22.66 | 557 | 22.50 | -4.3 | |
| 7 | | M. Jannis | 18.90 | 3.1 | 2021 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 8 | 7 | 7 | 3 | 4 | 0 | 0 | 0 | 21 | 0 | 2.70 | 10.80 | 0.25 | 8.10 | 4.8 | 19.0 | 3.60 | .385 | 18.90 | 429 | 17.86 | 394 | 21.60 | -4.6 | ||
| 8 | | J. Newberry | 16.62 | 4.1 | 2021 | 4 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 10 | 8 | 8 | 2 | 3 | 0 | 1 | 0 | 24 | 1 | 10.38 | 6.23 | 1.67 | 4.15 | 20.8 | 12.5 | 3.00 | .571 | 16.62 | 370 | 8.93 | 211 | 20.77 | -2.3 | ||
| 9 | | J. Guerra | 16.50 | 6.0 | 2021 | 6 | 0 | 1 | .000 | 0 | 4 | 0 | 0 | 0 | 12 | 11 | 13 | 3 | 3 | 3 | 1 | 0 | 37 | 1 | 6.00 | 4.50 | 1.33 | 4.50 | 10.8 | 8.1 | 2.50 | .375 | 19.50 | 393 | 11.33 | 265 | 18.00 | -4.6 | |
| 10 | | Z. Godley | 16.20 | 3.1 | 2021 | 2 | 0 | 1 | .000 | 1 | 5 | 0 | 0 | 0 | 4 | 6 | 7 | 2 | 5 | 1 | 0 | 0 | 21 | 2 | 13.50 | 13.50 | 1.00 | 5.40 | 23.8 | 23.8 | 2.70 | .250 | 18.90 | 386 | 13.36 | 312 | 10.80 | -3.3 | |
| 11 | | J. Weems | 15.88 | 5.2 | 2021 | TOT | 7 | 0 | 1 | .000 | 0 | 7 | 0 | 0 | 0 | 6 | 10 | 10 | 2 | 6 | 1 | 3 | 1 | 30 | 1 | 11.12 | 9.53 | 1.17 | 3.18 | 23.3 | 20.0 | 2.12 | .286 | 15.88 | 381 | 8.99 | 217 | 9.53 | -3.2 |
| 12 | | T. Hildenberger | 15.43 | 2.1 | 2021 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3 | 4 | 4 | 1 | 3 | 1 | 1 | 0 | 14 | 1 | 15.43 | 11.57 | 1.33 | 3.86 | 28.6 | 21.4 | 2.57 | .400 | 15.43 | 387 | 10.45 | 249 | 11.57 | -1.6 | ||
| 13 | | B. Peacock | 15.19 | 5.1 | 2021 | 2 | 0 | 1 | .000 | 1 | 3 | 0 | 0 | 0 | 6 | 9 | 9 | 2 | 3 | 1 | 1 | 0 | 26 | 0 | 5.06 | 5.06 | 1.00 | 3.38 | 11.5 | 11.5 | 1.69 | .235 | 15.19 | 332 | 9.16 | 212 | 10.13 | -2.8 | |
| 14 | | J. Nogowski | 15.00 | 3.0 | 2021 | TOT | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 5 | 5 | 0 | 0 | 0 | 3 | 0 | 16 | 0 | 0.00 | 0.00 | 0.00 | 0.0 | 0.0 | 2.67 | .500 | 15.00 | 354 | 3.16 | 75 | 24.00 | 0.4 | ||
| 15 | | J. Petricka | 15.00 | 6.0 | 2021 | 7 | 0 | 1 | .000 | 0 | 8 | 0 | 0 | 0 | 6 | 10 | 10 | 1 | 7 | 1 | 1 | 1 | 32 | 1 | 12.00 | 10.50 | 1.14 | 1.50 | 25.0 | 21.9 | 2.17 | .333 | 15.00 | 340 | 6.66 | 153 | 9.00 | -1.5 | |
| 16 | | S. Martinez | 15.00 | 3.0 | 2021 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5 | 5 | 5 | 0 | 3 | 0 | 3 | 0 | 16 | 0 | 9.00 | 9.00 | 1.00 | 0.00 | 18.8 | 18.8 | 2.67 | .500 | 15.00 | 351 | 4.16 | 98 | 15.00 | 0 | ||
| 17 | | T. Szapucki | 14.73 | 3.2 | 2021 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 7 | 6 | 6 | 2 | 3 | 0 | 0 | 0 | 20 | 0 | 9.82 | 7.36 | 1.33 | 4.91 | 20.0 | 15.0 | 2.73 | .455 | 14.73 | 369 | 10.53 | 251 | 17.18 | -2.6 | ||
| 18 | | B. Kriske | 14.29 | 11.1 | 2021 | TOT | 12 | 2 | 1 | .667 | 0 | 11 | 0 | 0 | 0 | 17 | 18 | 19 | 7 | 6 | 1 | 8 | 0 | 56 | 5 | 8.74 | 4.76 | 1.83 | 5.56 | 19.6 | 10.7 | 2.03 | .323 | 15.09 | 334 | 11.10 | 254 | 13.50 | -8.3 |
| 19 | | M. Sceroler | 14.09 | 7.2 | 2021 | 5 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 15 | 12 | 15 | 6 | 7 | 1 | 3 | 0 | 48 | 1 | 12.91 | 8.22 | 1.57 | 7.04 | 22.9 | 14.6 | 2.87 | .391 | 17.61 | 320 | 13.60 | 300 | 17.61 | -7.3 | ||
| 20 | | B. Burrows | 13.91 | 11.0 | 2021 | TOT | 6 | 0 | 1 | .000 | 1 | 8 | 0 | 0 | 0 | 16 | 17 | 18 | 5 | 10 | 0 | 2 | 0 | 58 | 0 | 6.55 | 8.18 | 0.80 | 4.09 | 13.8 | 17.2 | 2.36 | .314 | 14.73 | 324 | 10.34 | 244 | 13.09 | -7.5 |
| 21 | | M. Barreda | 13.50 | 2.2 | 2021 | 3 | 1 | 0 | 1.000 | 0 | 2 | 0 | 0 | 0 | 4 | 4 | 4 | 2 | 2 | 0 | 2 | 0 | 14 | 0 | 6.75 | 6.75 | 1.00 | 6.75 | 14.3 | 14.3 | 2.25 | .250 | 13.50 | 306 | 13.66 | 301 | 13.50 | -2.5 | |
| 22 | | A. Bellatti | 13.50 | 3.1 | 2021 | 3 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6 | 5 | 5 | 0 | 2 | 0 | 0 | 0 | 19 | 0 | 10.80 | 5.40 | 2.00 | 0.00 | 21.1 | 10.5 | 2.40 | .462 | 13.50 | 322 | 2.56 | 62 | 16.20 | 0.6 | ||
| 23 | | B. Dickson | 13.50 | 2.0 | 2021 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 3 | 3 | 1 | 0 | 0 | 1 | 0 | 10 | 0 | 4.50 | 0.00 | 4.50 | 10.0 | 0.0 | 2.50 | .500 | 13.50 | 332 | 8.66 | 208 | 22.50 | -1 | |||
| 24 | | J. Hahn | 13.50 | 3.1 | 2021 | 5 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 5 | 5 | 5 | 2 | 4 | 1 | 1 | 0 | 19 | 1 | 8.10 | 10.80 | 0.75 | 5.40 | 15.8 | 21.1 | 2.70 | .333 | 13.50 | 300 | 13.66 | 323 | 13.50 | -3.5 | ||
| 25 | | M. Kickham | 13.50 | 2.0 | 2021 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 5 | 3 | 3 | 1 | 1 | 1 | 1 | 0 | 12 | 0 | 9.00 | 4.50 | 2.00 | 4.50 | 16.7 | 8.3 | 3.00 | .571 | 13.50 | 332 | 10.66 | 249 | 22.50 | -1.4 | ||
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
80 | 82 | .494 | 14.0 | |
77 | 85 | .475 | 17.0 | |
74 | 88 | .457 | 20.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 103 | 59 | .636 | |
 Cubs - w | 89 | 73 | .549 | 14.0 |
82 | 80 | .506 | 21.0 | |
77 | 85 | .475 | 26.0 | |
75 | 87 | .463 | 28.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 100 | 62 | .617 | |
 Padres - w | 91 | 71 | .562 | 9.0 |
86 | 76 | .531 | 14.0 | |
65 | 97 | .401 | 35.0 | |
58 | 104 | .358 | 42.0 |
Diamondbacks
Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Rays - y | 98 | 64 | .605 | |
 Yankees - w | 93 | 68 | .578 | 4.5 |
 Red Sox - w | 87 | 75 | .537 | 11.0 |
79 | 82 | .491 | 18.5 | |
79 | 83 | .488 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 85 | 77 | .525 | |
 White Sox - w | 84 | 78 | .519 | 1.0 |
77 | 85 | .475 | 8.0 | |
76 | 86 | .469 | 9.0 | |
69 | 93 | .426 | 16.0 | |
| AL West | W | L | PCT | GB |
 Astros - y | 81 | 81 | .500 | |
80 | 82 | .494 | 1.0 | |
76 | 86 | .469 | 5.0 | |
64 | 98 | .395 | 17.0 | |
62 | 100 | .383 | 19.0 |
Blue Jays
Twins
Tigers
Rangers
Mariners