Chris Sale has the highest career K/9, with 11.11 per nine innings.

Interpreted as:

highest k/9 with a minimum of 1500 IP by a player in a MLB all-time

	NAME	K/9	IP	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Chris Sale C. Sale	11.11	2047.2	387	143	87	.622	307	3.02	2,528	16	3	12	1,668	686	739	209	481	126	25	15	8,249	47	2.11	5.26	0.92	30.6	5.8	1.05	.297	3.25	71	2.88	69	7.33	297.2
2	Jacob deGrom J. deGrom	10.83	1507.1	242	94	62	.603	242	2.54	1,814	4	2	0	1,151	426	463	139	338	25	0	13	5,919	28	2.02	5.37	0.83	30.6	5.7	0.99	.281	2.76	65	2.66	65	6.87	239.8
3	Max Scherzer M. Scherzer	10.62	2932.0	476	218	114	.657	467	3.17	3,459	12	5	0	2,392	1,033	1,106	346	768	114	2	20	11,845	79	2.36	4.50	1.06	29.2	6.5	1.08	.286	3.39	76	3.20	77	7.34	307.5
4	Randy Johnson R. Johnson	10.61	4135.1	618	303	166	.646	603	3.29	4,875	100	37	2	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
5	Yu Darvish Y. Darvish	10.53	1739.2	289	112	91	.552	289	3.62	2,036	2	1	0	1,424	699	733	221	555	79	0	8	7,149	82	2.87	3.67	1.14	28.5	7.8	1.14	.283	3.79	86	3.54	84	7.37	125.7
6	Gerrit Cole G. Cole	10.37	1954.0	317	153	80	.657	317	3.18	2,251	8	5	0	1,627	690	740	217	500	61	0	8	7,861	58	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
7	Pedro Martinez P. Martinez	10.04	2827.1	476	219	100	.687	409	2.93	3,154	46	17	3	2,221	919	1,006	239	760	141	23	30	11,394	62	2.42	4.15	0.76	27.7	6.7	1.05	.279	3.20	66	2.91	68	7.07	454.6
8	Aaron Nola A. Nola	9.86	1671.0	277	105	86	.550	277	3.78	1,831	6	4	0	1,482	701	739	210	437	55	0	16	6,855	18	2.35	4.19	1.13	26.7	6.4	1.15	.294	3.98	90	3.49	81	7.98	146.1
9	Clayton Kershaw C. Kershaw	9.64	2814.1	446	218	96	.694	443	2.52	3,014	25	15	0	2,162	787	864	233	697	46	1	28	11,112	107	2.23	4.32	0.75	27.1	6.3	1.02	.271	2.76	64	2.84	70	6.91	369.9
10	Nolan Ryan N. Ryan	9.55	5386.0	807	324	292	.526	773	3.19	5,714	222	61	3	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56	370.2
11	Zack Wheeler Z. Wheeler	9.48	1728.1	283	113	75	.601	283	3.28	1,820	5	3	0	1,475	630	683	166	490	76	0	14	7,086	41	2.55	3.71	0.86	25.7	6.9	1.14	.289	3.56	82	3.28	80	7.68	164.4
12	Corey Kluber C. Kluber	9.46	1641.2	271	116	77	.601	260	3.44	1,725	18	8	1	1,486	627	684	177	368	65	4	9	6,688	31	2.02	4.69	0.97	25.8	5.5	1.13	.301	3.75	83	3.22	78	8.15	161.7
13	Tim Lincecum T. Lincecum	9.29	1682.0	278	110	89	.553	270	3.74	1,736	10	7	1	1,506	699	746	147	669	44	3	33	7,120	107	3.58	2.59	0.79	24.4	9.4	1.29	.300	3.99	99	3.44	90	8.06	81.5
14	Sandy Koufax S. Koufax	9.28	2324.1	397	165	87	.655	314	2.76	2,396	137	40	9	1,754	713	806	204	817	18	44	48	9,497	87	3.16	2.93	0.79	25.2	8.6	1.11	.256	3.12	75	2.69	75	6.79	226.6
15	Kevin Gausman K. Gausman	9.20	1860.2	353	110	111	.498	314	3.84	1,903	3	1	0	1,790	793	849	231	525	38	11	11	7,785	63	2.54	3.62	1.12	24.4	6.7	1.24	.306	4.11	93	3.63	86	8.66	122
16	Carlos Carrasco C. Carrasco	9.05	1687.1	335	112	105	.516	286	4.22	1,696	11	4	2	1,673	792	832	221	468	56	23	21	7,073	61	2.50	3.62	1.18	24.0	6.6	1.27	.313	4.44	102	3.76	90	8.92	74.1
17	Lance Lynn L. Lynn	9.04	2006.1	364	143	99	.591	340	3.74	2,015	4	2	1	1,856	834	916	231	704	89	4	21	8,520	61	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
18	Francisco Liriano F. Liriano	9.01	1813.2	419	112	114	.496	300	4.15	1,815	3	1	1	1,649	837	911	184	816	62	19	15	7,781	100	4.05	2.22	0.91	23.3	10.5	1.36	.299	4.52	101	3.88	95	8.18	39.3
19	Sonny Gray S. Gray	9.00	1872.2	331	122	99	.552	322	3.55	1,872	7	5	0	1,624	738	809	184	605	57	2	5	7,751	105	2.91	3.09	0.88	24.2	7.8	1.19	.286	3.89	86	3.49	84	7.80	136.6
20	Justin Verlander J. Verlander	8.97	3515.0	546	263	156	.628	546	3.33	3,503	26	9	0	3,004	1,302	1,410	367	988	120	0	27	14,389	99	2.53	3.55	0.94	24.3	6.9	1.14	.280	3.61	79	3.43	81	7.69	306.1
21	Sam McDowell S. McDowell	8.86	2492.1	425	141	134	.513	346	3.17	2,453	103	23	14	1,948	879	999	164	1,312	59	39	74	10,587	140	4.74	1.87	0.59	23.2	12.4	1.31	.270	3.61	90	3.06	84	7.03	160.4
22	Johan Santana J. Santana	8.83	2025.2	360	139	78	.641	284	3.20	1,988	15	10	1	1,726	721	773	220	567	36	23	13	8,262	68	2.52	3.51	0.98	24.1	6.9	1.13	.276	3.43	74	3.43	81	7.67	187.6
23	Hideo Nomo H. Nomo	8.73	1976.1	323	123	109	.530	318	4.24	1,918	16	9	0	1,768	932	993	251	908	38	2	31	8,462	109	4.13	2.11	1.14	22.7	10.7	1.35	.284	4.52	102	4.22	98	8.05	14.5
24	David Price D. Price	8.72	2143.2	400	157	82	.657	322	3.32	2,076	17	3	3	1,930	790	865	221	562	63	19	16	8,807	40	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
25	Charlie Morton C. Morton	8.70	2243.1	409	146	133	.523	402	4.08	2,169	3	2	0	2,114	1,016	1,115	221	840	198	1	27	9,633	70	3.37	2.58	0.89	22.5	8.7	1.32	.305	4.47	101	3.87	96	8.48	42.4