Lou Gehrig has the highest career OPS + 100 in the postseason when making 100+ plate appearances, with 101.21.

Interpreted as:

highest postseason ops+ 100 by a player pas

	NAME	OPS+100	PA	OPS	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG
1	Lou Gehrig L. Gehrig	101.21	150	1.214	34	119	30	43	8	3	10	35	26	2	17	0	1	87	21	1		2	1	.361	.483	.731
2	Babe Ruth B. Ruth	101.21	167	1.214	41	129	37	42	5	2	15	33	33	2	30	4	3	96	22	2		2	3	.326	.470	.744
3	Lenny Dykstra L. Dykstra	101.09	136	1.094	32	112	27	36	6	1	10	19	20	2	23	5	0	74	17	2	0	3	0	.321	.433	.661
4	Vladimir Guerrero Jr. V. Guerrero Jr.	101.09	114	1.091	24	95	19	32	6	0	8	16	16	2	12	0	0	62	14	0	1	7	2	.337	.439	.653
5	Paul Molitor P. Molitor	101.05	132	1.050	29	117	28	43	5	3	6	22	12	2	15	3	2	72	14	1	0	1	2	.368	.435	.615
6	Hank Greenberg H. Greenberg	101.04	101	1.044	23	85	17	27	7	2	5	22	13	2	19	1	0	53	14	1		0	4	.318	.420	.624
7	George Brett G. Brett	101.02	184	1.023	43	166	30	56	8	5	10	23	17	0	20	2	3	104	23	0	1	6	4	.337	.397	.627
8	Carlos Beltran C. Beltran	101.02	256	1.021	65	215	45	66	15	1	16	42	37	2	33	11	0	131	32	1	1	2	3	.307	.412	.609
9	Albert Pujols A. Pujols	100.99	360	.995	88	304	57	97	18	1	19	54	50	5	46	1	2	174	38	0	1	20	7	.319	.422	.572
10	Daniel Murphy D. Murphy	100.99	113	.986	25	97	21	30	3	0	8	19	15	0	21	3	2	57	11	0	1	4	1	.309	.398	.588
11	Bryce Harper B. Harper	100.99	250	.986	57	208	42	57	14	1	17	34	38	2	56	8	1	124	32	1	1	4	5	.274	.390	.596
12	Nelson Cruz N. Cruz	100.98	207	.979	50	187	35	52	12	0	18	38	19	1	45	1	1	118	30	0	0	2	5	.278	.348	.631
13	Nomar Garciaparra N. Garciaparra	100.98	127	.975	32	112	16	36	7	1	7	24	12	1	18	2	0	66	15	0	2	4	3	.321	.386	.589
14	Gene Woodling G. Woodling	100.97	104	.972	26	85	21	27	5	2	3	6	19	0	8	0	1	45	10	0		2	0	.318	.442	.529
15	Will Clark W. Clark	100.96	132	.956	31	117	20	39	8	1	5	16	13	2	19	1	1	64	14	0	0	3	2	.333	.409	.547
16	Rafael Devers R. Devers	100.96	102	.955	26	89	21	27	0	0	8	26	12	0	25	1	0	51	8	0	1	0	1	.303	.382	.573
17	Lance Berkman L. Berkman	100.95	224	.949	52	186	38	59	11	1	9	41	31	3	41	4	1	99	21	0	3	6	4	.317	.417	.532
18	David Ortiz D. Ortiz	100.95	369	.947	85	304	51	88	22	2	17	61	59	2	72	0	1	165	41	0	4	11	4	.289	.404	.543
19	Dave Henderson D. Henderson	100.95	141	.946	36	121	24	36	10	1	7	20	14	3	35	1	0	69	18	0	3	1	2	.298	.376	.570
20	Randy Arozarena R. Arozarena	100.95	184	.946	45	161	33	47	6	1	12	19	17	6	52	8	2	91	19	0	0	2	3	.292	.380	.565
21	Duke Snider D. Snider	100.95	149	.945	36	133	21	38	8	0	11	26	13	1	33	1	0	79	19	1	1	4	2	.286	.351	.594
22	Yordan Alvarez Y. Alvarez	100.94	252	.944	60	214	39	63	13	3	12	41	31	5	69	0	0	118	28	0	2	5	1	.294	.393	.551
23	Kevin Youkilis K. Youkilis	100.94	125	.944	29	111	22	34	9	1	6	17	13	0	18	0	0	63	16	0	1	0	4	.306	.376	.568
24	Shohei Ohtani S. Ohtani	100.94	159	.940	33	129	27	32	4	1	11	24	29	1	45	1	3	71	16	0	0	9	0	.248	.390	.550
25	Manny Ramirez M. Ramirez	100.94	493	.937	111	410	67	117	19	0	29	78	72	5	91	1	1	223	48	0	6	12	17	.285	.394	.544