The Cleveland Indians have a 42-36 record on April 21 all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Indians	4/21/1915	1-0	CLE	@	SLA	W 3-1	1.000	22	3	6	1	0	0		3	0	0	0		27	7	1	2				.273	.360	.318	.678
2	Indians	4/21/1916	0-1	CLE	@	SLA	L 1-11	.000	27	1	1	1	0	0		5	0	0	3		33	2	1	1				.037	.188	.074	.262
3	Indians	4/21/1917	0-1	CLE	vs	DET	L 4-5	.000	30	4	6	0	1	0	3	7	2	2	2		40	8	1	1				.200	.385	.267	.651
4	Indians	4/21/1918	0-1	CLE	vs	SLA	L 7-11	.000	33	7	11	3	0	0	6	10	1	4	1		44	14	3	0				.333	.500	.424	.924
5	Indians	4/21/1921	1-0	CLE	vs	SLA	W 4-3	1.000	32	4	11	7	0	0	4	2	0	2	0	0	37	18	7	3				.344	.382	.563	.945
6	Indians	4/21/1922	0-1	CLE	@	DET	L 7-15	.000	36	7	16	2	0	0	7	4	1	1	0	0	44	18	2	3				.444	.512	.500	1.012
7	Indians	4/21/1923	1-0	CLE	vs	CWS	W 5-1	1.000	31	5	11	1	0	0	5	2	0	1	1	2	35	12	1	2				.355	.394	.387	.781
8	Indians	4/21/1925	0-1	CLE	@	DET	L 3-4	.000	35	3	10	2	0	1	3	4	0	2	0	2	39	15	3	0				.286	.359	.429	.788
9	Indians	4/21/1926	1-0	CLE	vs	DET	W 12-2	1.000	37	12	16	7	0	0	10	6	0	1	0	0	46	23	7	3				.432	.512	.622	1.133
10	Indians	4/21/1930	1-0	CLE	@	DET	W 6-1	1.000	34	6	10	2	0	0	5	1	1	0	0	0	38	12	2	2				.294	.333	.353	.686
11	Indians	4/21/1931	1-0	CLE	vs	DET	W 5-4	1.000	30	5	8	2	1	0	5	5	0	1	1	0	38	12	3	3				.267	.371	.400	.771
12	Indians	4/21/1932	0-1	CLE	vs	DET	L 3-5	.000	32	3	7	2	0	0	3	5	0	5	0	0	37	9	2	0				.219	.324	.281	.606
13	Indians	4/21/1933	1-0	CLE	vs	DET	W 5-0	1.000	30	5	9	3	0	1	3	0	0	9	0	1	31	15	4	1				.300	.300	.500	.800
14	Indians	4/21/1935	0-1	CLE	@	DET	L 2-3	.000	46	2	10	1	0	1	2	3	0	5	1	1	49	14	2	0				.217	.265	.304	.570
15	Indians	4/21/1938	1-0	CLE	vs	SLA	W 4-3	1.000	34	4	11	4	0	0	4	5	0	5	0	0	39	15	4	0				.324	.410	.441	.851
16	Indians	4/21/1939	1-0	CLE	vs	DET	W 5-1	1.000	35	5	11	3	1	0	5	3	0	4	0	0	38	16	4	0			0	.314	.368	.457	.826
17	Indians	4/21/1940	0-1	CLE	vs	DET	L 2-12	.000	31	2	5	2	0	1	2	2	0	1	0	0	33	10	3	0			0	.161	.212	.323	.535
18	Indians	4/21/1942	1-0	CLE	vs	SLA	W 4-2	1.000	31	4	7	2	0	0	3	4	0	1	0	0	35	9	2	0			0	.226	.314	.290	.605
19	Indians	4/21/1943	1-0	CLE	vs	DET	W 1-0	1.000	29	1	6	1	0	0	1	5	0	2	0	1	36	7	1	2			0	.207	.324	.241	.565
20	Indians	4/21/1944	1-0	CLE	vs	DET	W 7-4	1.000	35	7	12	2	0	1	7	1	0	3	0	0	37	17	3	1			1	.343	.361	.486	.847
21	Indians	4/21/1945	0-1	CLE	@	DET	L 2-3	.000	38	2	5	2	0	0	1	5	0	8	0	0	44	7	2	1			0	.132	.233	.184	.417
22	Indians	4/21/1946	0-1	CLE	vs	DET	L 2-3	.000	33	2	4	0	0	0	2	4	0	6	0	0	38	4	0	1			1	.121	.216	.121	.337
23	Indians	4/21/1949	1-0	CLE	@	SLA	W 8-2	1.000	34	8	10	4	0	2	8	10	0	4	0	2	45	20	6	1			0	.294	.455	.588	1.043
24	Indians	4/21/1951	0-1	CLE	vs	SLA	L 1-9	.000	30	1	5	0	0	0	1	3	0	3	0	0	33	5	0	0		0	2	.167	.242	.167	.409
25	Indians	4/21/1953	1-0	CLE	vs	SLA	W 4-3	1.000	29	4	7	3	0	0	3	4	0	3	0	1	34	10	3	1		0	0	.241	.333	.345	.678
	Total		42-36					.538	2,611	369	688	131	12	74		306	21	370	43	22	3,006	1,065	217	51	17	9	43	.264	.343	.408	.751