Pedro Martinez has struck out the most hitters in a game on April 8, with 16 strikeouts against the Tampa Bay Devil Rays on April 8, 2001.
| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Martinez | 16 | 4/8/2001 |  BOS | vs |  TBD | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 29 | 0 |
| 2 |  | J. Moyer | 13 | 4/8/1989 |  TEX | vs |  TOR | W | 1 | 4.50 | 0 | 0 | 0 | 8.0 | 4 | 4 | 4 | 1 | 3 | 0 | 0 | 0 | 31 | 0 |
| 3 |  | N. Ryan | 13 | 4/8/1978 |  CAL | vs |  OAK | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 24 | 0 | |
| 4 |  | N. Lodolo | 12 | 4/8/2023 |  CIN | @ |  PHI | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 27 | 0 | |
| 5 |  | S. Ohtani | 12 | 4/8/2018 |  LAA | vs | OAK | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 23 | 0 |
| 6 | | D. Selma | 12 | 4/8/1969 |  SDP | vs |  HOU | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 5 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 34 | 0 |
| 7 |  | C. Ragans | 11 | 4/8/2025 |  KCR | vs |  MIN | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 23 | 0 | |
| 8 | | L. Lynn | 11 | 4/8/2021 |  CWS | vs | KCR | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 32 | 0 |
| 9 |  | B. Snell | 11 | 4/8/2019 |  TBR | @ | CWS | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 6 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 23 | 1 |
| 10 | | P. Astacio | 11 | 4/8/1994 |  LAD | vs |  ATL | L | 1 | 4.70 | 0 | 0 | 0 | 7.2 | 5 | 4 | 4 | 3 | 2 | 0 | 0 | 0 | 29 | 0 |
| 11 |  | N. Ryan | 11 | 4/8/1988 |  HOU | @ | CIN | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 4 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 27 | 1 | |
| 12 | | F. Viola | 11 | 4/8/1987 |  MIN | vs | OAK | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 5 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 25 | 0 |
| 13 | | P. Jarvis | 11 | 4/8/1970 | ATL | @ | SDP | W | 1 | 0.00 | 1 | 0 | 0 | 9.0 | 5 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 33 | 0 |
| 14 |  | C. Holmes | 10 | 4/8/2025 |  NYM | vs |  MIA | W | 1 | 6.75 | 0 | 0 | 0 | 5.1 | 5 | 4 | 4 | 0 | 3 | 0 | 0 | 0 | 23 | 0 |
| 15 |  | Z. Gallen | 10 | 4/8/2024 |  ARI | @ |  COL | 1 | 5.40 | 0 | 0 | 0 | 5.0 | 8 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 23 | 0 | |
| 16 |  | J. Ryan | 10 | 4/8/2023 | MIN | vs |  HOU | W | 1 | 6.00 | 0 | 0 | 0 | 6.0 | 3 | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 23 | 0 |
| 17 |  | M. Wacha | 10 | 4/8/2023 |  SDP | @ | ATL | W | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 21 | 0 |
| 18 | | C. Carrasco | 10 | 4/8/2015 |  CLE | @ | HOU | W | 1 | 0.00 | 0 | 0 | 0 | 6.1 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 23 | 0 |
| 19 | | S. Kazmir | 10 | 4/8/2015 | OAK | vs |  TEX | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 25 | 0 |
| 20 | | J. Garcia | 10 | 4/8/2013 |  STL | vs | CIN | 1 | 4.05 | 0 | 0 | 0 | 6.2 | 6 | 3 | 3 | 1 | 3 | 0 | 0 | 0 | 29 | 1 | |
| 21 | | S. Kazmir | 10 | 4/8/2007 | TBD | vs |  TOR | L | 1 | 5.14 | 0 | 0 | 0 | 7.0 | 6 | 4 | 4 | 2 | 2 | 0 | 0 | 0 | 29 | 1 |
| 22 | | A. Harang | 10 | 4/8/2006 | CIN | vs |  PIT | W | 1 | 6.75 | 0 | 0 | 0 | 6.2 | 8 | 5 | 5 | 1 | 0 | 0 | 0 | 0 | 28 | 0 |
| 23 | | K. Mercker | 10 | 4/8/1994 | ATL | @ | LAD | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 31 | 0 |
| 24 | | J. McDowell | 10 | 4/8/1991 | CWS | @ |  BAL | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 4 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 32 | 1 |
| 25 | | N. Ryan | 10 | 4/8/1987 | HOU | vs | LAD | W | 1 | 3.86 | 0 | 0 | 0 | 7.0 | 8 | 3 | 3 | 0 | 1 | 0 | 0 | 1 | 30 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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