Ben Sheets has fanned the most hitters in a game on May 16, with 18 strikeouts against the Braves on May 16, 2004.
| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | B. Sheets | 18 | 5/16/2004 |  MIL | vs |  ATL | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 31 | 0 |
| 2 | | M. Mussina | 14 | 5/16/1993 |  BAL | @ |  DET | W | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 6 | 2 | 2 | 2 | 2 | 0 | 0 | 0 | 30 | 1 |
| 3 |  | R. Johnson | 14 | 5/16/1993 |  SEA | @ |  OAK | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 30 | 0 |
| 4 | | B. Hurst | 14 | 5/16/1986 |  BOS | vs |  TEX | L | 1 | 3.00 | 1 | 0 | 0 | 9.0 | 8 | 3 | 4 | 3 | 0 | 0 | 0 | 0 | 35 | 0 |
| 5 | | J. Schmidt | 13 | 5/16/2003 |  SFG | vs |  NYM | 1 | 6.75 | 0 | 0 | 0 | 6.2 | 6 | 5 | 5 | 2 | 2 | 0 | 0 | 0 | 28 | 0 | |
| 6 | | R. Guidry | 13 | 5/16/1979 |  NYY | vs | DET | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 9 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 34 | 0 |
| 7 |  | T. Seaver | 13 | 5/16/1978 |  CIN | @ |  MON | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 7 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 34 | 0 |
| 8 | | B. Veale | 13 | 5/16/1968 |  PIT | vs |  STL | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 8 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 36 | 0 |
| 9 |  | S. Koufax | 13 | 5/16/1957 |  BKN | @ |  CHC | W | 1 | 0.00 | 1 | 0 | 0 | 9.0 | 4 | 0 | 2 | 0 | 7 | 0 | 0 | 0 | 39 | 0 |
| 10 |  | R. Johnson | 12 | 5/16/2000 |  ARI | @ | MON | L | 1 | 1.13 | 1 | 0 | 0 | 8.0 | 5 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 28 | 0 |
| 11 |  | N. Pivetta | 11 | 5/16/2018 |  PHI | @ | BAL | W | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 24 | 0 |
| 12 |  | M. Scherzer | 11 | 5/16/2015 |  WSH | @ |  SDP | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 4 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 27 | 1 |
| 13 |  | Y. Darvish | 11 | 5/16/2014 |  TEX | vs |  TOR | L | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 5 | 2 | 2 | 0 | 3 | 0 | 0 | 1 | 31 | 0 |
| 14 | | C. Hamels | 11 | 5/16/2007 | PHI | vs | MIL | W | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 2 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 27 | 0 |
| 15 | | R. Oswalt | 11 | 5/16/2002 |  HOU | vs | PIT | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 7 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 31 | 0 |
| 16 | | A. Benes | 11 | 5/16/1997 | STL | @ | ATL | 1 | 0.00 | 0 | 0 | 0 | 9.0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 31 | 0 | |
| 17 |  | J. Morris | 11 | 5/16/1987 | DET | vs |  CLE | W | 1 | 3.00 | 1 | 0 | 0 | 9.0 | 5 | 3 | 3 | 3 | 2 | 1 | 0 | 0 | 36 | 1 |
| 18 |  | N. Ryan | 11 | 5/16/1984 |  HOU | @ | PIT | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 31 | 0 |
| 19 | | G. Perry | 11 | 5/16/1982 |  SEA | vs |  BAL | L | 1 | 4.82 | 0 | 0 | 0 | 9.1 | 8 | 5 | 5 | 2 | 5 | 0 | 0 | 0 | 41 | 1 |
| 20 | | M. Paul | 11 | 5/16/1969 | CLE | vs | OAK | L | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 4 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 27 | 0 |
| 21 | | S. McDowell | 11 | 5/16/1967 | CLE | @ | NYY | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 6 | 2 | 3 | 0 | 7 | 0 | 0 | 0 | 36 | 0 | |
| 22 | | M. McDermott | 11 | 5/16/1952 |  BSA | @ |  SLA | L | 1 | 1.93 | 0 | 0 | 0 | 9.1 | 3 | 2 | 2 | 1 | 7 | 0 | 0 | 0 | 38 | 0 |
| 23 |  | C. Burnes | 10 | 5/16/2025 |  AZ | vs |  COL | W | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 23 | 0 |
| 24 |  | K. Gausman | 10 | 5/16/2023 | TOR | vs | NYY | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 5 | 2 | 3 | 1 | 2 | 0 | 0 | 0 | 26 | 0 | |
| 25 |  | F. Peralta | 10 | 5/16/2022 |  MIL | vs | ATL | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 24 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Cubs 
Dodgers 
Padres 
Red Sox 
Guardians 
Astros 
KCR 
CWS 
