Alex Rodriguez has launched the most career home runs against the Angels, with 70 homers.

Interpreted as:

most home runs by a player vs angels all-time

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Alex Rodriguez A. Rodriguez	70	207	806	173	257	44	3	169	90	19	189	25	11	929	517	117	2	12	6	14	.319	.395	.641	1.036
2	Nelson Cruz N. Cruz	51	192	702	108	200	28	0	127	59	8	179	13	3	774	381	79	1	4	4	14	.285	.345	.543	.888
3	Rafael Palmeiro R. Palmeiro	49	210	771	126	228	40	2	153	109	7	85	6	3	895	419	91	1	7	8	15	.296	.385	.543	.928
4	Adrian Beltre A. Beltre	48	261	1,011	133	276	52	4	168	73	10	162	13	3	1,101	480	104	0	7	6	24	.273	.326	.475	.801
5	Harmon Killebrew H. Killebrew	45	225	741	102	186	24	1	122	166	4	169	1	2	917	347	70	0	6	20	23	.251	.388	.468	.857
6	Reggie Jackson R. Jackson	40	206	745	118	198	35	8	131	106	11	212	24	12	869	369	83	3	4	6	12	.266	.364	.495	.859
7	Cal Ripken Jr. C. Ripken Jr.	38	235	894	127	266	45	2	157	89	7	86	1	2	1,010	429	85	1	19	5	34	.298	.359	.480	.839
8	Juan Gonzalez J. Gonzalez	36	142	546	83	169	29	1	120	43	4	108	4	5	598	308	66	0	5	7	14	.310	.361	.564	.925
9	Jose Canseco J. Canseco	36	151	541	91	140	21	0	107	95	13	168	14	9	654	269	57	0	5	6	17	.259	.379	.497	.876
10	Willie Horton W. Horton	36	186	655	74	188	17	0	114	63	3	125	2	2	727	313	53	1	5	3	12	.287	.350	.478	.828
11	Carl Yastrzemski C. Yastrzemski	36	280	988	135	281	53	5	164	169	4	127	14	9	1,169	452	94	1	7	16	19	.284	.389	.457	.846
12	Frank Thomas F. Thomas	35	173	600	109	193	34	3	122	134	6	100	3	2	751	338	72	0	11	12	14	.322	.443	.563	1.007
13	David Ortiz D. Ortiz	32	126	448	79	122	24	2	91	69	2	110	0	1	526	246	58	0	7	8	10	.272	.367	.549	.916
14	Albert Belle A. Belle	32	108	403	58	116	15	1	115	53	5	60	8	0	471	229	48	0	10	6	10	.288	.369	.568	.938
15	Sal Bando S. Bando	31	210	736	92	177	34	4	122	106	9	139	8	4	862	312	69	4	7	9	12	.240	.340	.424	.764
16	Boog Powell B. Powell	31	179	594	79	162	22	0	109	86	2	122	0	4	694	277	53	3	9	12	17	.273	.362	.466	.828
17	George Springer G. Springer	30	127	480	90	123	10	4	76	64	7	111	8	4	556	231	44	0	5	1	18	.256	.349	.481	.830
18	Hank Blalock H. Blalock	30	123	471	75	139	31	2	82	45	1	80	1	1	519	264	63	0	2	2	8	.295	.356	.561	.917
19	Ken Griffey Jr. K. Griffey Jr.	30	133	490	86	133	26	0	93	63	5	88	13	4	567	249	56	1	8	7	15	.271	.355	.508	.863
20	Al Kaline A. Kaline	30	175	610	102	167	24	5	94	90	6	61	8	3	710	291	59	2	2	10	16	.274	.371	.477	.849
21	Mark McGwire M. McGwire	29	108	363	66	93	17	0	81	83	6	84	1	0	455	197	46	0	3	7	11	.256	.400	.543	.943
22	Eddie Murray E. Murray	29	155	579	93	188	33	2	111	82	1	76	10	1	671	312	64	0	9	18	19	.325	.404	.539	.943
23	Jason Giambi J. Giambi	28	150	491	73	131	35	0	79	94	15	97	1	1	606	250	63	1	5	8	12	.267	.397	.509	.906
24	Jim Thome J. Thome	28	120	411	67	115	23	1	81	72	2	126	0	1	490	224	52	0	5	7	8	.280	.386	.545	.931
25	Marcus Semien M. Semien	27	161	629	110	177	40	4	87	79	2	121	16	2	715	306	71	2	3	0	7	.281	.362	.486	.848