Since 1979, Brooks Kieschnick has the highest OPS by a pitcher when making 50+ plate appearances, with an OPS of .837.

	NAME	OPS	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	WRC	WRAA	WOBA	WRC+	BRAA
1	Brooks Kieschnick B. Kieschnick	.837	144	144	133	14	38	4	0	8	19	11	0	29	0	0	66	12	0	0	1	5	.286	.340	.496	21	3.4	.358	114	2.7
2	Micah Owings M. Owings	.813	219	174	205	27	58	14	2	9	35	8	1	72	0	0	103	25	3	2	0	2	.283	.310	.502	30	3.7	.347	104	1.6
3	Ron Reed R. Reed	.747	53	275	45	2	14	4	0	0	4	3	0	13	0	0	18	4	4	1	0	0	.311	.347	.400	6	0.5	.335	106	0.3
4	Brandon Backe B. Backe	.731	158	109	133	22	34	5	2	4	16	10	2	48	1	0	55	11	13	0	0	1	.256	.317	.414	18	-0.9	.321	92	-1.6
5	Brad Woodall B. Woodall	.718	60	59	48	7	13	1	0	1	3	7	0	12	0	0	17	2	5	0	0	0	.271	.364	.354	7	-0.2	.330	94	-0.4
6	Renie Martin R. Martin	.711	90	88	83	8	25	3	3	0	4	0	0	23	2	0	34	6	7	0	0	0	.301	.301	.410	10	-0.5	.313	96	-0.4
7	Michael Lorenzen M. Lorenzen	.710	147	321	133	20	31	3	1	7	24	7	2	47	5	2	57	11	5	0	0	5	.233	.282	.429	16	-1.7	.304	84	-3
8	Dontrelle Willis D. Willis	.665	447	198	389	43	95	13	6	9	39	22	2	69	0	1	147	28	33	1	0	5	.244	.287	.378	41	-13.5	.291	75	-14.6
9	Tim Lollar T. Lollar	.662	255	124	231	27	54	3	3	8	38	18	0	64	0	0	87	14	3	3	0	3	.234	.286	.377	24	-4	.297	88	-3.3
10	Dan Schatzeder D. Schatzeder	.654	216	355	191	19	46	6	2	4	21	16	0	60	0	0	68	12	8	1	0	3	.241	.298	.356	21	-4	.296	85	-3.9
11	Mike Hampton M. Hampton	.650	845	412	725	97	178	22	5	16	79	47	5	195	3	4	258	43	63	5	0	12	.246	.294	.356	74	-31.9	.289	67	-35.5
12	Dennis Cook D. Cook	.638	122	394	110	15	29	2	1	2	9	3	0	13	0	0	39	5	9	0	0	3	.264	.283	.355	10	-3.1	.286	73	-3.4
13	Allen Watson A. Watson	.636	197	104	175	13	45	13	1	0	19	9	0	22	0	0	60	14	13	0	0	8	.257	.293	.343	16	-8.4	.285	68	-8
14	Carlos Zambrano C. Zambrano	.636	744	365	693	75	165	26	3	24	71	10	0	240	1	0	269	53	37	4	0	14	.238	.248	.388	55	-34.2	.273	57	-40.3
15	Tom Urbani T. Urbani	.627	79	67	65	6	16	1	0	1	4	7	0	18	0	0	20	2	7	0	0	0	.246	.319	.308	7	-2.7	.290	73	-2.7
16	Mark Bomback M. Bomback	.615	53	37	43	5	10	3	0	0	5	3	2	15	0	0	13	3	5	0	0	0	.233	.313	.302	5	-1.3	.289	79	-1.2
17	Steven Brault S. Brault	.612	101	103	89	11	23	4	0	1	4	2	0	15	0	0	30	5	10	0	0	1	.258	.275	.337	8	-4.3	.263	62	-4.8
18	Omar Olivares O. Olivares	.608	263	220	242	25	58	10	1	5	29	6	0	71	0	0	85	16	14	1	0	1	.240	.257	.351	19	-11.2	.269	61	-11.9
19	Zack Greinke Z. Greinke	.598	600	260	521	49	117	29	1	9	34	26	2	114	9	1	175	39	47	4	0	8	.225	.262	.336	42	-27	.261	59	-29.9
20	Rick Rhoden R. Rhoden	.597	579	248	536	39	133	31	0	5	49	12	0	68	0	1	179	36	27	4	0	15	.248	.263	.334	43	-22.4	.266	64	-23.9
21	Don Robinson D. Robinson	.596	576	513	546	45	126	21	0	13	66	16	2	146	0	1	186	34	11	1	1	6	.231	.255	.341	42	-22.9	.267	65	-23.1
22	Brian Bohanon B. Bohanon	.584	265	144	231	16	53	11	1	3	30	10	0	69	0	0	75	15	22	2	0	5	.229	.259	.325	16	-18	.257	32	-23.9
23	Willie Hernandez W. Hernandez	.581	50	269	46	3	12	2	0	0	3	1	0	20	2	0	14	2	3	0	0	0	.261	.277	.304	3	-2.3	.263	52	-2.7
24	Chris Hammond C. Hammond	.575	286	276	238	30	48	7	1	4	14	28	0	96	0	0	69	12	19	1	0	2	.202	.285	.290	20	-13.8	.268	59	-14.3
25	Roger McDowell R. McDowell	.574	83	620	72	6	16	5	0	0	6	5	1	28	0	0	21	5	5	0	0	0	.222	.282	.292	6	-3.9	.264	63	-3.6