5 players are tied for the most RBIs in a loss, with 8 RBIs. The first three are Shohei Ohtani on June 21, 2022, Jason Bay on September 19, 2003 and Mike Epstein on June 19, 1970.

Interpreted as:

most rbi in a regular-season loss all-time by a player

	NAME	RBI	L	DATE	TM		OPP	W	L%	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Shohei Ohtani S. Ohtani	8	1	6/21/2022	LAA	vs	KCR	0	1.000	4	2	3	0	0	2	0	0	0	0	0	6	9	2	0	2	0	0
2	Jason Bay J. Bay	8	1	9/19/2003	PIT	vs	CHC	0	1.000	4	2	3	1	0	2	0	0	1	0	0	4	10	3	0	0	0	0
3	Mike Epstein M. Epstein	8	1	6/19/1970	WSH	@	BAL	0	1.000	4	2	3	0	0	2	1	0	0	0	0	5	9	2	0	0	0	0
4	Lee Thomas L. Thomas	8	1	9/5/1961	LAA	@	KCA	0	1.000	6	3	4	0	0	3	0	0	1	0	0	6	13	3	0	0	0	0
5	Lou Gehrig L. Gehrig	8	1	9/9/1932	NYY	@	DET	0	1.000	6	2	2	1	0	1	2	0	0	0	0	8	6	2	0
6	Austin Riley A. Riley	7	1	7/18/2023	ATL	vs	ARI	0	1.000	5	3	3	1	0	2	0	0	1	0	0	5	10	3	0	0	0	0
7	Nelson Cruz N. Cruz	7	1	6/22/2018	SEA	@	BOS	0	1.000	5	2	4	0	0	2	0	0	0	0	0	5	10	2	0	0	0	0
8	J.P. Arencibia	7	1	7/29/2014	TEX	vs	NYY	0	1.000	5	2	4	2	0	2	0	0	1	0	0	5	12	4	0	0	0	0
9	Jonathan Lucroy J. Lucroy	7	1	8/30/2012	MIL	@	CHC	0	1.000	5	1	3	0	0	1	0	0	0	0	0	5	6	1	0	0	0	0
10	Carlos Ruiz C. Ruiz	7	1	5/2/2012	PHI	@	ATL	0	1.000	5	2	3	2	0	1	0	1	0	0	0	6	8	3	0	0	0	1
11	Justin Morneau J. Morneau	7	1	7/20/2009	MIN	@	OAK	0	1.000	5	4	3	1	0	2	1	0	1	0	0	6	10	3	0	0	0	0
12	Jose Guillen J. Guillen	7	1	6/7/2008	KCR	@	NYY	0	1.000	4	2	3	0	0	2	0	0	0	0	0	4	9	2	0	0	0	0
13	Albert Pujols A. Pujols	7	1	8/22/2006	STL	@	NYM	0	1.000	4	2	2	0	0	2	0	0	1	0	0	4	8	2	0	0	0	1
14	Tadahito Iguchi T. Iguchi	7	1	6/25/2006	CWS	vs	HOU	0	1.000	5	2	2	0	0	2	1	0	0	0	0	6	8	2	0	0	0	0
15	Ryan Howard R. Howard	7	1	6/20/2006	PHI	vs	NYY	0	1.000	4	2	3	0	1	2	1	0	0	0	0	5	11	3	0	0	1	0
16	Juan Uribe J. Uribe	7	1	6/19/2004	CWS	@	MON	0	1.000	6	1	3	1	0	1	0	0	2	0	0	6	7	2	0	0	0	0
17	Carlos Pena C. Pena	7	1	5/19/2003	DET	@	CLE	0	1.000	4	3	3	0	0	3	1	0	0	0	0	5	12	3	0	0	0	0
18	Phil Nevin P. Nevin	7	1	9/27/2001	SDP	@	COL	0	1.000	5	2	3	1	0	2	0	0	0	0	0	5	10	3	0	0	0	0
19	Bernie Williams B. Williams	7	1	6/17/2000	NYY	vs	CWS	0	1.000	4	3	4	2	0	1	1	0	0	0	0	5	9	3	0	0	0	0
20	Henry Rodriguez H. Rodriguez	7	1	5/14/2000	CHC	@	MON	0	1.000	6	2	4	0	0	2	0	0	1	0	0	6	10	2	0	0	0	0
21	Gary Sheffield G. Sheffield	7	1	9/18/1995	FLA	@	PHI	0	1.000	3	3	3	0	0	2	1	0	0	2	0	5	9	2	0	1	0	0
22	Mike Stanley M. Stanley	7	1	8/10/1995	NYY	vs	CLE	0	1.000	4	3	3	0	0	3	0	0	0	0	0	4	12	3	0	0	0	0
23	Troy Neel T. Neel	7	1	7/8/1993	OAK	vs	BOS	0	1.000	5	2	4	0	0	2	0	0	1	0	0	5	10	2	0	0	0	0
24	Rafael Ramirez R. Ramirez	7	1	8/29/1989	HOU	@	CHC	0	1.000	5	1	3	1	0	1	0	0	0	0	0	5	7	2	0	0	0	0
25	Todd Benzinger T. Benzinger	7	1	9/15/1987	BOS	@	DET	0	1.000	4	1	3	0	0	1	0	0	0	0	0	4	6	1	0	0	0	0