Between April 19, 1996 and April 28, 2023, Max Scherzer and Randy Johnson were tied for striking out the most hitters, with 3,210 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Scherzer | 3,210 | 434 | 203 | 103 | .663 | 425 | 3.12 | 12 | 5 | 0 | 2701.1 | 2,194 | 935 | 1,006 | 304 | 710 | 107 | 2 | 20 | 10,908 | 74 | 10.69 | 2.37 | 4.52 | 1.01 | 29.4 | 6.5 | 1.08 | .287 | 3.35 | 7.31 |
| 2 |  | R. Johnson | 3,210 | 396 | 201 | 102 | .663 | 383 | 3.18 | 59 | 22 | 1 | 2646.2 | 2,207 | 934 | 1,057 | 290 | 730 | 123 | 5 | 28 | 10,770 | 50 | 10.92 | 2.48 | 4.40 | 0.99 | 29.8 | 6.8 | 1.11 | .299 | 3.59 | 7.50 |
| 3 |  | J. Verlander | 3,198 | 482 | 244 | 133 | .647 | 482 | 3.24 | 26 | 9 | 0 | 3163.0 | 2,654 | 1,139 | 1,235 | 322 | 880 | 104 | 0 | 27 | 12,880 | 90 | 9.10 | 2.50 | 3.63 | 0.92 | 24.8 | 6.8 | 1.12 | .278 | 3.51 | 7.55 |
| 4 |  | CC Sabathia | 3,093 | 561 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3577.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,989 | 74 | 7.78 | 2.76 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.56 |
| 5 |  | Z. Greinke | 2,904 | 562 | 223 | 145 | .606 | 520 | 3.45 | 17 | 5 | 1 | 3278.0 | 3,088 | 1,256 | 1,350 | 349 | 745 | 75 | 8 | 25 | 13,419 | 99 | 7.97 | 2.05 | 3.90 | 0.96 | 21.6 | 5.6 | 1.17 | .293 | 3.71 | 8.48 |
| 6 |  | C. Kershaw | 2,839 | 406 | 201 | 88 | .696 | 403 | 2.48 | 25 | 15 | 0 | 2612.0 | 1,977 | 719 | 788 | 210 | 634 | 40 | 1 | 27 | 10,281 | 96 | 9.78 | 2.18 | 4.48 | 0.72 | 27.6 | 6.2 | 1.00 | .269 | 2.72 | 6.81 |
| 7 |  | P. Martinez | 2,693 | 352 | 184 | 78 | .702 | 350 | 2.84 | 43 | 14 | 0 | 2357.0 | 1,848 | 744 | 821 | 200 | 585 | 115 | 1 | 22 | 9,477 | 48 | 10.28 | 2.23 | 4.60 | 0.76 | 28.4 | 6.2 | 1.03 | .280 | 3.13 | 7.06 |
| 8 |  | C. Hamels | 2,560 | 423 | 163 | 122 | .572 | 422 | 3.43 | 17 | 7 | 0 | 2698.0 | 2,424 | 1,027 | 1,103 | 310 | 767 | 100 | 0 | 43 | 11,115 | 57 | 8.54 | 2.56 | 3.34 | 1.03 | 23.0 | 6.9 | 1.18 | .287 | 3.68 | 8.09 |
| 9 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 10 |  | B. Colon | 2,535 | 565 | 247 | 188 | .568 | 552 | 4.12 | 38 | 13 | 0 | 3461.2 | 3,593 | 1,584 | 1,719 | 439 | 948 | 64 | 2 | 47 | 14,655 | 45 | 6.59 | 2.46 | 2.67 | 1.14 | 17.3 | 6.5 | 1.31 | .296 | 4.47 | 9.34 |
| 11 |  | F. Hernandez | 2,524 | 419 | 169 | 136 | .554 | 418 | 3.42 | 25 | 11 | 0 | 2729.2 | 2,487 | 1,037 | 1,157 | 264 | 805 | 105 | 0 | 16 | 11,284 | 156 | 8.32 | 2.65 | 3.14 | 0.87 | 22.4 | 7.1 | 1.21 | .293 | 3.81 | 8.20 |
| 12 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 13 | | C. Schilling | 2,498 | 363 | 173 | 104 | .625 | 341 | 3.43 | 64 | 14 | 9 | 2456.0 | 2,267 | 935 | 970 | 283 | 470 | 40 | 21 | 20 | 9,933 | 49 | 9.15 | 1.72 | 5.31 | 1.04 | 25.1 | 4.7 | 1.11 | .299 | 3.55 | 8.31 |
| 14 |  | J. Lester | 2,488 | 452 | 200 | 117 | .631 | 451 | 3.66 | 15 | 4 | 0 | 2740.0 | 2,610 | 1,114 | 1,215 | 294 | 892 | 90 | 0 | 13 | 11,487 | 63 | 8.17 | 2.93 | 2.79 | 0.97 | 21.7 | 7.8 | 1.28 | .300 | 3.99 | 8.57 |
| 15 | | A. Pettitte | 2,321 | 497 | 241 | 144 | .626 | 492 | 3.84 | 23 | 4 | 0 | 3120.0 | 3,244 | 1,331 | 1,480 | 272 | 962 | 54 | 2 | 39 | 13,245 | 61 | 6.70 | 2.78 | 2.41 | 0.78 | 17.5 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 16 |  | R. Clemens | 2,319 | 356 | 172 | 83 | .675 | 355 | 3.25 | 24 | 10 | 0 | 2359.1 | 2,020 | 852 | 933 | 186 | 814 | 75 | 0 | 21 | 9,774 | 78 | 8.85 | 3.11 | 2.85 | 0.71 | 23.7 | 8.3 | 1.20 | .287 | 3.56 | 7.71 |
| 17 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 18 | | M. Mussina | 2,239 | 408 | 196 | 122 | .616 | 407 | 3.85 | 33 | 13 | 0 | 2638.1 | 2,634 | 1,128 | 1,213 | 287 | 576 | 52 | 0 | 20 | 10,887 | 55 | 7.64 | 1.96 | 3.89 | 0.98 | 20.6 | 5.3 | 1.22 | .304 | 4.14 | 8.99 |
| 19 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
| 20 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 21 | | A. Wainwright | 2,147 | 457 | 195 | 117 | .625 | 390 | 3.38 | 28 | 11 | 3 | 2567.1 | 2,426 | 964 | 1,028 | 213 | 695 | 80 | 13 | 40 | 10,632 | 50 | 7.53 | 2.44 | 3.09 | 0.75 | 20.2 | 6.5 | 1.22 | .295 | 3.60 | 8.50 |
| 22 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 23 |  | C. Sale | 2,094 | 328 | 115 | 77 | .599 | 248 | 3.10 | 16 | 3 | 12 | 1701.0 | 1,392 | 586 | 634 | 183 | 397 | 106 | 25 | 15 | 6,862 | 38 | 11.08 | 2.10 | 5.27 | 0.97 | 30.5 | 5.8 | 1.05 | .296 | 3.35 | 7.37 |
| 24 | | K. Millwood | 2,083 | 451 | 169 | 152 | .526 | 443 | 4.11 | 22 | 6 | 0 | 2720.1 | 2,770 | 1,243 | 1,357 | 296 | 843 | 74 | 3 | 46 | 11,616 | 67 | 6.89 | 2.79 | 2.47 | 0.98 | 17.9 | 7.3 | 1.33 | .297 | 4.49 | 9.16 |
| 25 | | T. Hudson | 2,080 | 482 | 222 | 133 | .625 | 479 | 3.49 | 26 | 13 | 0 | 3126.2 | 2,957 | 1,213 | 1,319 | 248 | 917 | 124 | 0 | 84 | 13,005 | 84 | 5.99 | 2.64 | 2.27 | 0.71 | 16.0 | 7.1 | 1.24 | .281 | 3.80 | 8.51 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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