Between July 4, 1998 and May 13, 2025, Justin Verlander struck out the most hitters, with 3,456 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Verlander | 3,456 | 535 | 262 | 150 | .636 | 535 | 3.31 | 26 | 9 | 0 | 3463.2 | 2,940 | 1,275 | 1,379 | 363 | 968 | 116 | 0 | 27 | 14,150 | 97 | 8.98 | 2.52 | 3.57 | 0.94 | 24.4 | 6.8 | 1.13 | .279 | 3.58 | 7.64 |
| 2 |  | M. Scherzer | 3,408 | 467 | 215 | 112 | .657 | 458 | 3.16 | 12 | 5 | 0 | 2881.0 | 2,349 | 1,012 | 1,085 | 337 | 756 | 112 | 2 | 20 | 11,640 | 78 | 10.65 | 2.36 | 4.51 | 1.05 | 29.3 | 6.5 | 1.08 | .286 | 3.39 | 7.34 |
| 3 |  | CC Sabathia | 3,093 | 561 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3577.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,989 | 74 | 7.78 | 2.76 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.56 |
| 4 |  | Z. Greinke | 2,979 | 586 | 225 | 156 | .591 | 541 | 3.49 | 17 | 5 | 1 | 3389.1 | 3,207 | 1,315 | 1,410 | 367 | 762 | 79 | 8 | 25 | 13,877 | 101 | 7.91 | 2.02 | 3.91 | 0.97 | 21.5 | 5.5 | 1.17 | .293 | 3.74 | 8.52 |
| 5 |  | C. Kershaw | 2,968 | 432 | 212 | 94 | .693 | 429 | 2.50 | 25 | 15 | 0 | 2742.2 | 2,091 | 762 | 835 | 227 | 678 | 44 | 1 | 28 | 10,816 | 103 | 9.74 | 2.22 | 4.38 | 0.74 | 27.4 | 6.3 | 1.01 | .270 | 2.74 | 6.86 |
| 6 |  | R. Johnson | 2,717 | 338 | 172 | 91 | .654 | 332 | 3.15 | 52 | 20 | 0 | 2283.1 | 1,909 | 800 | 907 | 251 | 593 | 101 | 3 | 26 | 9,260 | 39 | 10.71 | 2.34 | 4.58 | 0.99 | 29.3 | 6.4 | 1.10 | .296 | 3.58 | 7.52 |
| 7 |  | C. Hamels | 2,560 | 423 | 163 | 122 | .572 | 422 | 3.43 | 17 | 7 | 0 | 2698.0 | 2,424 | 1,027 | 1,103 | 310 | 767 | 100 | 0 | 43 | 11,115 | 57 | 8.54 | 2.56 | 3.34 | 1.03 | 23.0 | 6.9 | 1.18 | .287 | 3.68 | 8.09 |
| 8 |  | F. Hernandez | 2,524 | 419 | 169 | 136 | .554 | 418 | 3.42 | 25 | 11 | 0 | 2729.2 | 2,487 | 1,037 | 1,157 | 264 | 805 | 105 | 0 | 16 | 11,284 | 156 | 8.32 | 2.65 | 3.14 | 0.87 | 22.4 | 7.1 | 1.21 | .293 | 3.81 | 8.20 |
| 9 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 10 |  | J. Lester | 2,488 | 452 | 200 | 117 | .631 | 451 | 3.66 | 15 | 4 | 0 | 2740.0 | 2,610 | 1,114 | 1,215 | 294 | 892 | 90 | 0 | 13 | 11,487 | 63 | 8.17 | 2.93 | 2.79 | 0.97 | 21.7 | 7.8 | 1.28 | .300 | 3.99 | 8.57 |
| 11 |  | C. Sale | 2,478 | 381 | 139 | 86 | .618 | 301 | 3.06 | 16 | 3 | 12 | 2006.0 | 1,644 | 682 | 735 | 207 | 468 | 124 | 25 | 15 | 8,091 | 47 | 11.12 | 2.10 | 5.29 | 0.93 | 30.6 | 5.8 | 1.05 | .299 | 3.30 | 7.38 |
| 12 | | J. Vazquez | 2,458 | 432 | 162 | 154 | .513 | 425 | 4.17 | 28 | 8 | 0 | 2742.0 | 2,677 | 1,269 | 1,366 | 356 | 726 | 84 | 5 | 57 | 11,514 | 76 | 8.07 | 2.38 | 3.39 | 1.17 | 21.3 | 6.3 | 1.24 | .294 | 4.48 | 8.79 |
| 13 |  | B. Colon | 2,371 | 529 | 234 | 177 | .569 | 518 | 4.14 | 32 | 11 | 0 | 3243.1 | 3,386 | 1,491 | 1,614 | 420 | 862 | 58 | 2 | 44 | 13,719 | 36 | 6.58 | 2.39 | 2.75 | 1.17 | 17.3 | 6.3 | 1.31 | .296 | 4.48 | 9.40 |
| 14 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 15 |  | G. Cole | 2,251 | 317 | 153 | 80 | .657 | 317 | 3.18 | 8 | 5 | 0 | 1954.0 | 1,627 | 690 | 740 | 217 | 500 | 61 | 0 | 7 | 7,861 | 58 | 10.37 | 2.30 | 4.50 | 1.00 | 28.6 | 6.4 | 1.09 | .292 | 3.41 | 7.49 |
| 16 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
| 17 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 18 | | A. Wainwright | 2,202 | 478 | 200 | 128 | .610 | 411 | 3.53 | 28 | 11 | 3 | 2668.1 | 2,577 | 1,047 | 1,117 | 233 | 736 | 81 | 13 | 40 | 11,116 | 51 | 7.43 | 2.48 | 2.99 | 0.79 | 19.8 | 6.6 | 1.24 | .298 | 3.77 | 8.69 |
| 19 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 20 | | T. Hudson | 2,080 | 482 | 222 | 133 | .625 | 479 | 3.49 | 26 | 13 | 0 | 3126.2 | 2,957 | 1,213 | 1,319 | 248 | 917 | 124 | 0 | 84 | 13,005 | 84 | 5.99 | 2.64 | 2.27 | 0.71 | 16.0 | 7.1 | 1.24 | .281 | 3.80 | 8.51 |
| 21 |  | C. Morton | 2,077 | 393 | 138 | 130 | .515 | 388 | 4.09 | 3 | 2 | 0 | 2159.1 | 2,035 | 981 | 1,079 | 211 | 809 | 188 | 1 | 25 | 9,268 | 69 | 8.66 | 3.37 | 2.57 | 0.88 | 22.4 | 8.7 | 1.32 | .305 | 4.50 | 8.48 |
| 22 |  | D. Price | 2,076 | 400 | 157 | 82 | .657 | 322 | 3.32 | 17 | 3 | 3 | 2143.2 | 1,930 | 790 | 865 | 221 | 562 | 63 | 19 | 16 | 8,807 | 40 | 8.72 | 2.36 | 3.69 | 0.93 | 23.6 | 6.4 | 1.16 | .290 | 3.63 | 8.10 |
| 23 |  | M. Bumgarner | 2,070 | 358 | 134 | 124 | .519 | 355 | 3.47 | 16 | 7 | 0 | 2209.1 | 2,007 | 853 | 933 | 258 | 544 | 89 | 1 | 38 | 9,098 | 29 | 8.43 | 2.22 | 3.81 | 1.05 | 22.8 | 6.0 | 1.15 | .285 | 3.80 | 8.18 |
| 24 | | R. Dempster | 2,053 | 571 | 131 | 130 | .502 | 345 | 4.32 | 11 | 3 | 87 | 2355.1 | 2,311 | 1,130 | 1,224 | 262 | 1,049 | 84 | 186 | 46 | 10,259 | 77 | 7.84 | 4.01 | 1.96 | 1.00 | 20.0 | 10.2 | 1.43 | .301 | 4.68 | 8.83 |
| 25 |  | P. Martinez | 2,042 | 273 | 143 | 59 | .708 | 271 | 2.89 | 25 | 8 | 0 | 1789.2 | 1,420 | 575 | 627 | 151 | 420 | 98 | 1 | 13 | 7,200 | 36 | 10.27 | 2.11 | 4.86 | 0.76 | 28.4 | 5.8 | 1.03 | .283 | 3.15 | 7.14 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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