Between July 1, 1936 and September 29, 1963, Bob Feller struck out the most batters, with 2,581 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | B. Feller | 2,581 | 570 | 266 | 162 | .621 | 484 | 3.26 | 279 | 44 | 22 | 3827.0 | 3,271 | 1,385 | 1,557 | 223 | 1,764 | 60 | 52 | 6 | 16,172 | 69 | 6.07 | 4.15 | 1.46 | 0.52 | 16.0 | 10.9 | 1.32 | .264 | 3.66 | 7.69 |
| 2 | | W. Spahn | 2,415 | 676 | 350 | 216 | .618 | 610 | 2.98 | 370 | 62 | 24 | 4872.1 | 4,419 | 1,611 | 1,804 | 385 | 1,324 | 36 | 53 | 19,950 | 70 | 4.46 | 2.45 | 1.82 | 0.71 | 12.1 | 6.6 | 1.18 | .255 | 3.33 | 8.16 | |
| 3 | | E. Wynn | 2,340 | 691 | 300 | 244 | .551 | 611 | 3.54 | 289 | 49 | 15 | 4564.0 | 4,292 | 1,793 | 2,037 | 339 | 1,775 | 64 | 67 | 19,406 | 53 | 4.61 | 3.50 | 1.32 | 0.67 | 12.1 | 9.1 | 1.33 | .266 | 4.02 | 8.46 | |
| 4 | | R. Roberts | 2,102 | 591 | 258 | 221 | .539 | 532 | 3.42 | 287 | 37 | 24 | 4182.0 | 4,067 | 1,588 | 1,754 | 454 | 798 | 49 | 44 | 17,130 | 28 | 4.52 | 1.72 | 2.63 | 0.98 | 12.3 | 4.7 | 1.16 | .263 | 3.77 | 8.75 | |
| 5 | | B. Pierce | 1,969 | 551 | 208 | 169 | .552 | 432 | 3.28 | 193 | 38 | 29 | 3257.2 | 2,949 | 1,186 | 1,310 | 278 | 1,169 | 30 | 71 | 13,656 | 47 | 5.44 | 3.23 | 1.68 | 0.77 | 14.4 | 8.6 | 1.26 | .262 | 3.62 | 8.15 | |
| 6 | | H. Newhouser | 1,795 | 488 | 207 | 150 | .580 | 374 | 3.06 | 212 | 33 | 26 | 2993.0 | 2,675 | 1,016 | 1,197 | 137 | 1,248 | 19 | 79 | 1 | 12,643 | 65 | 5.40 | 3.75 | 1.44 | 0.41 | 14.2 | 9.9 | 1.31 | .269 | 3.60 | 8.04 |
| 7 | | B. Newsom | 1,774 | 491 | 175 | 175 | .500 | 401 | 3.91 | 203 | 24 | 12 | 3098.2 | 3,071 | 1,347 | 1,539 | 174 | 1,400 | 56 | 52 | 13,555 | 43 | 5.15 | 4.07 | 1.27 | 0.51 | 13.1 | 10.3 | 1.44 | .285 | 4.47 | 8.92 | |
| 8 | | W. Ford | 1,561 | 393 | 199 | 78 | .718 | 350 | 2.78 | 133 | 34 | 9 | 2564.1 | 2,194 | 793 | 899 | 186 | 946 | 25 | 25 | 34 | 10,544 | 59 | 5.48 | 3.32 | 1.65 | 0.65 | 14.8 | 9.0 | 1.22 | .257 | 3.16 | 7.70 |
| 9 | | V. Trucks | 1,535 | 517 | 177 | 135 | .567 | 328 | 3.38 | 124 | 33 | 30 | 2682.1 | 2,416 | 1,007 | 1,125 | 189 | 1,088 | 49 | 114 | 20 | 11,381 | 64 | 5.15 | 3.65 | 1.41 | 0.63 | 13.5 | 9.6 | 1.31 | .261 | 3.77 | 8.11 |
| 10 | | C. Pascual | 1,521 | 348 | 113 | 120 | .485 | 249 | 3.67 | 98 | 29 | 10 | 1938.2 | 1,800 | 790 | 876 | 163 | 718 | 37 | 59 | 8,231 | 51 | 7.06 | 3.33 | 2.12 | 0.76 | 18.5 | 8.7 | 1.30 | .283 | 4.07 | 8.36 | |
| 11 | | D. Drysdale | 1,487 | 313 | 123 | 90 | .577 | 262 | 3.11 | 93 | 22 | 5 | 1945.0 | 1,752 | 673 | 771 | 175 | 547 | 93 | 33 | 66 | 8,064 | 43 | 6.88 | 2.53 | 2.72 | 0.81 | 18.4 | 6.8 | 1.18 | .274 | 3.57 | 8.11 |
| 12 | | B. Friend | 1,480 | 499 | 170 | 188 | .475 | 408 | 3.58 | 140 | 30 | 9 | 3017.2 | 3,135 | 1,201 | 1,388 | 246 | 772 | 33 | 46 | 88 | 12,722 | 47 | 4.41 | 2.30 | 1.92 | 0.73 | 11.6 | 6.1 | 1.29 | .283 | 4.14 | 9.35 |
| 13 |  | S. Koufax | 1,474 | 284 | 93 | 65 | .589 | 204 | 3.32 | 68 | 20 | 6 | 1442.2 | 1,143 | 532 | 593 | 146 | 616 | 13 | 41 | 35 | 6,056 | 60 | 9.20 | 3.84 | 2.39 | 0.91 | 24.3 | 10.2 | 1.22 | .262 | 3.70 | 7.13 |
| 14 | | H. Haddix | 1,465 | 380 | 128 | 106 | .547 | 286 | 3.69 | 99 | 20 | 10 | 2111.2 | 2,055 | 865 | 964 | 231 | 554 | 39 | 46 | 8,821 | 53 | 6.24 | 2.36 | 2.64 | 0.98 | 16.6 | 6.3 | 1.24 | .279 | 4.11 | 8.76 | |
| 15 | | A. Reynolds | 1,423 | 434 | 182 | 107 | .630 | 309 | 3.30 | 137 | 36 | 48 | 2492.0 | 2,193 | 913 | 1,026 | 133 | 1,261 | 56 | 97 | 10,654 | 59 | 5.14 | 4.55 | 1.13 | 0.48 | 13.4 | 11.8 | 1.39 | .265 | 3.71 | 7.92 | |
| 16 | | C. Simmons | 1,416 | 441 | 156 | 143 | .522 | 363 | 3.45 | 138 | 31 | 4 | 2674.0 | 2,596 | 1,026 | 1,220 | 191 | 895 | 38 | 43 | 11,327 | 33 | 4.77 | 3.01 | 1.58 | 0.64 | 12.5 | 7.9 | 1.31 | .274 | 4.11 | 8.74 | |
| 17 | | J. Bunning | 1,406 | 304 | 118 | 87 | .576 | 251 | 3.44 | 78 | 16 | 12 | 1867.0 | 1,692 | 714 | 796 | 223 | 564 | 73 | 27 | 31 | 7,812 | 26 | 6.78 | 2.72 | 2.49 | 1.07 | 18.0 | 7.2 | 1.21 | .265 | 3.84 | 8.16 |
| 18 | | S. Jones | 1,372 | 315 | 102 | 101 | .502 | 222 | 3.59 | 76 | 17 | 10 | 1633.0 | 1,396 | 652 | 749 | 150 | 817 | 60 | 41 | 37 | 7,035 | 45 | 7.56 | 4.50 | 1.68 | 0.83 | 19.5 | 11.6 | 1.36 | .269 | 4.13 | 7.69 |
| 19 | | J. Vander Meer | 1,303 | 346 | 119 | 121 | .496 | 286 | 3.44 | 131 | 29 | 2 | 2103.2 | 1,800 | 804 | 915 | 99 | 1,132 | 23 | 28 | 9,061 | 37 | 5.57 | 4.84 | 1.15 | 0.42 | 14.4 | 12.5 | 1.39 | .262 | 3.91 | 7.70 | |
| 20 | | M. Dickson | 1,289 | 625 | 172 | 181 | .487 | 338 | 3.69 | 149 | 27 | 23 | 3052.2 | 3,027 | 1,250 | 1,431 | 302 | 1,059 | 36 | 148 | 12,948 | 34 | 3.80 | 3.12 | 1.22 | 0.89 | 10.0 | 8.2 | 1.34 | .266 | 4.22 | 8.92 | |
| 21 | | B. Lemon | 1,278 | 460 | 207 | 128 | .618 | 350 | 3.24 | 188 | 31 | 22 | 2851.1 | 2,559 | 1,025 | 1,184 | 180 | 1,251 | 57 | 73 | 12,106 | 63 | 4.03 | 3.95 | 1.02 | 0.57 | 10.6 | 10.3 | 1.34 | .255 | 3.74 | 8.08 | |
| 22 | | J. Podres | 1,267 | 336 | 129 | 96 | .573 | 286 | 3.66 | 72 | 22 | 5 | 1891.0 | 1,876 | 770 | 853 | 193 | 627 | 23 | 22 | 7,990 | 50 | 6.03 | 2.98 | 2.02 | 0.92 | 15.9 | 7.8 | 1.32 | .286 | 4.06 | 8.93 | |
| 23 | | B. Turley | 1,265 | 310 | 101 | 85 | .543 | 237 | 3.64 | 78 | 24 | 13 | 1713.0 | 1,365 | 693 | 752 | 140 | 1,068 | 56 | 38 | 21 | 7,445 | 39 | 6.65 | 5.61 | 1.18 | 0.74 | 17.0 | 14.3 | 1.42 | .249 | 3.95 | 7.17 |
| 24 | | D. Trout | 1,256 | 521 | 170 | 161 | .514 | 322 | 3.26 | 158 | 28 | 37 | 2725.2 | 2,641 | 986 | 1,169 | 112 | 1,047 | 34 | 134 | 0 | 11,612 | 50 | 4.15 | 3.46 | 1.20 | 0.37 | 10.8 | 9.0 | 1.35 | .276 | 3.86 | 8.72 |
| 25 | | B. Rush | 1,249 | 417 | 127 | 152 | .455 | 321 | 3.65 | 118 | 16 | 8 | 2410.2 | 2,338 | 978 | 1,128 | 176 | 788 | 34 | 44 | 30 | 10,224 | 52 | 4.66 | 2.94 | 1.59 | 0.66 | 12.2 | 7.7 | 1.30 | .271 | 4.21 | 8.73 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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