Reggie Jackson has the most career strikeouts in the month of September, with 473 strikeouts.

Interpreted as:

most strikeouts by a player in september all-time

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reggie Jackson R. Jackson	473	487	1,677	253	421	70	2	98	293	205	13	45	12	1,911	789	170	4	12	33	26	.251	.335	.470	.806
2	Alex Rodriguez A. Rodriguez	410	467	1,713	320	476	74	5	113	364	244	30	57	10	2,014	899	192	3	24	17	34	.278	.373	.525	.898
3	Jim Thome J. Thome	399	409	1,339	255	352	53	6	93	277	269	12	2	3	1,634	696	152	0	14	21	25	.263	.387	.520	.907
4	Mike Schmidt M. Schmidt	376	426	1,474	246	373	56	12	97	282	277	12	46	20	1,787	744	165	3	21	44	23	.253	.371	.505	.876
5	Dave Kingman D. Kingman	370	370	1,295	163	310	55	8	70	192	123	7	15	9	1,443	591	133	3	15	15	29	.239	.306	.456	.762
6	Adam Dunn A. Dunn	359	302	999	133	210	50	0	43	128	181	14	7	3	1,195	389	93	0	1	17	19	.210	.339	.389	.728
7	Giancarlo Stanton G. Stanton	350	271	964	135	226	48	1	68	176	128	6	5	3	1,105	480	117	0	7	15	29	.234	.326	.498	.824
8	Willie Stargell W. Stargell	348	425	1,406	218	384	67	14	71	264	199	19	2	5	1,636	692	152	0	12	57	27	.273	.368	.492	.860
9	Miguel Cabrera M. Cabrera	347	468	1,720	266	525	88	0	87	330	207	15	7	1	1,961	874	175	2	17	44	55	.305	.381	.508	.889
10	Andres Galarraga A. Galarraga	347	367	1,310	196	381	80	7	55	228	87	19	27	13	1,431	640	142	0	15	19	29	.291	.340	.489	.829
11	Curtis Granderson C. Granderson	335	382	1,288	223	312	64	16	67	178	157	14	19	4	1,467	609	147	3	5	5	12	.242	.330	.473	.803
12	Bobby Bonds B. Bonds	333	320	1,197	205	278	46	6	60	170	167	4	74	22	1,374	516	112	2	4	12	25	.232	.327	.431	.758
13	Nelson Cruz N. Cruz	330	367	1,318	207	375	64	5	73	209	124	8	10	6	1,463	668	142	1	12	13	34	.285	.347	.507	.854
14	Paul Goldschmidt P. Goldschmidt	329	329	1,180	201	320	88	6	47	174	172	6	29	3	1,371	561	141	0	13	22	37	.271	.363	.475	.839
15	Derek Jeter D. Jeter	323	454	1,775	330	559	87	7	42	213	201	32	56	15	2,030	786	136	12	10	5	43	.315	.392	.443	.835
16	Jose Canseco J. Canseco	323	305	1,103	175	281	46	3	63	217	130	18	26	16	1,267	522	112	0	16	13	20	.255	.339	.473	.812
17	Sammy Sosa S. Sosa	321	331	1,158	210	290	30	3	74	202	133	8	43	13	1,310	548	107	1	10	29	27	.250	.329	.473	.802
18	Harmon Killebrew H. Killebrew	321	441	1,445	249	365	42	2	115	269	284	4	3	3	1,744	756	159	0	11	22	26	.253	.374	.523	.898
19	Jayson Werth J. Werth	319	333	1,190	189	299	57	7	43	171	174	15	33	4	1,388	499	107	3	6	5	24	.251	.352	.419	.772
20	Evan Longoria E. Longoria	318	381	1,381	178	349	72	4	62	219	138	18	8	4	1,556	615	138	0	19	14	49	.253	.325	.445	.770
21	David Ortiz D. Ortiz	317	421	1,470	247	425	108	2	99	314	223	4	1	1	1,713	834	209	1	15	44	35	.289	.381	.567	.948
22	J.D. Martinez	315	292	1,088	146	306	58	4	56	181	109	6	6	3	1,216	540	118	0	13	16	35	.281	.346	.496	.843
23	Chris Davis C. Davis	308	247	873	120	224	45	3	47	122	94	10	8	1	978	416	95	0	1	10	17	.257	.335	.477	.812
24	Ryan Howard R. Howard	306	279	945	159	254	57	5	73	213	157	12	3	1	1,120	540	135	0	6	44	22	.269	.378	.571	.949
25	Andrew McCutchen A. McCutchen	305	362	1,301	213	344	72	9	58	175	216	22	25	16	1,551	608	139	0	12	9	28	.264	.375	.467	.843