Phil Niekro has won the most career games by a pitcher 40 or older, with 121 wins.

Interpreted as:

most regular-season wins by a pitcher age 40+

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Phil Niekro P. Niekro	121	103	.540	300	294	3.84	1,148	62	11	1	1977.0	1,950	843	955	208	789	35	4	20	8,467	65	5.23	3.59	1.46	0.95	13.6	9.3	1.39	.277	4.35	8.88
2	Jamie Moyer J. Moyer	105	84	.556	257	251	4.44	913	8	2	0	1551.1	1,645	766	817	227	441	66	2	23	6,668	13	5.30	2.56	2.07	1.32	13.7	6.6	1.34	.282	4.74	9.54
3	Jack Quinn J. Quinn	104	90	.536	368	169	3.58	420	78	12	47	1566.0	1,805	623	777	52	343	44	129		6,751	20	2.41	1.97	1.22	0.30	6.2	5.1	1.37	.298	4.47	10.37
4	Randy Johnson R. Johnson	75	52	.591	167	162	3.83	1,030	13	3	0	1034.0	929	440	492	130	242	45	2	15	4,249	17	8.97	2.11	4.26	1.13	24.2	5.7	1.13	.285	4.28	8.09
5	Warren Spahn W. Spahn	75	62	.547	178	155	3.45	501	76	12	4	1153.0	1,133	442	490	120	274	11	17	15	4,756	18	3.91	2.14	1.83	0.94	10.5	5.8	1.22	.263	3.82	8.84
6	Bartolo Colon B. Colon	72	64	.529	175	168	4.28	672	5	3	0	1014.0	1,136	482	515	138	171	16	2	11	4,282	6	5.96	1.52	3.93	1.22	15.7	4.0	1.29	.304	4.57	10.08
7	Nolan Ryan N. Ryan	71	66	.518	196	196	3.33	1,437	19	7	0	1271.2	933	471	535	93	527	45	0	13	5,258	68	10.17	3.73	2.73	0.66	27.3	10.0	1.15	.266	3.79	6.60
8	Charlie Hough C. Hough	67	88	.432	209	207	4.06	756	29	3	0	1346.1	1,207	608	685	149	623	65	1	10	5,812	56	5.05	4.16	1.21	1.00	13.0	10.7	1.36	.251	4.58	8.07
9	Roger Clemens R. Clemens	66	36	.647	145	144	3.12	829	2	1	0	911.0	774	316	349	74	281	26	0	14	3,736	32	8.19	2.78	2.95	0.73	22.2	7.5	1.16	.277	3.45	7.65
10	Cy Young C. Young	54	45	.545	110	105	0.01	383	86	9	2	882.0	782		315	11	147	18	4		3,465	23	3.91	1.50	2.61	0.11	11.1	4.2	1.05	.265	3.21	7.98
11	Hoyt Wilhelm H. Wilhelm	52	41	.559	459	2	2.11	610	0	0	118	794.0	551	186	226	46	231	16	312	30	3,131	35	6.91	2.62	2.64	0.52	19.5	7.4	0.98	.227	2.56	6.25
12	Gaylord Perry G. Perry	50	59	.459	155	153	3.82	558	29	3	0	1025.2	1,113	435	497	86	261	24	2	22	4,348	36	4.90	2.29	2.14	0.75	12.8	6.0	1.34	.300	4.36	9.77
13	Tim Wakefield T. Wakefield	49	49	.500	151	128	4.83	486	4	0	0	814.2	826	437	480	108	265	42	16	5	3,510	53	5.37	2.93	1.83	1.19	13.8	7.5	1.34	.275	5.30	9.13
14	David Wells D. Wells	48	35	.578	125	124	4.50	392	4	0	0	758.0	895	379	396	94	112	18	0	6	3,214	9	4.65	1.33	3.50	1.12	12.2	3.5	1.33	.308	4.70	10.63
15	Tommy John T. John	48	58	.453	172	157	4.43	317	14	2	0	950.2	1,163	468	517	77	255	25	7	23	4,151	46	3.00	2.41	1.24	0.73	7.6	6.1	1.49	.312	4.89	11.01
16	Grover Alexander G. Alexander	46	30	.605	102	83	3.31	146	48	3	5	665.1	710	245	289	42	104	4	12		2,760	6	1.97	1.41	1.40	0.57	5.3	3.8	1.22	.271	3.91	9.60
17	Don Sutton D. Sutton	44	38	.537	119	118	4.06	366	5	2	0	712.0	703	321	339	101	179	11	0	8	2,971	19	4.63	2.26	2.04	1.28	12.3	6.0	1.24	.260	4.29	8.89
18	Kenny Rogers K. Rogers	43	33	.566	105	104	4.29	304	1	1	0	636.0	677	303	337	68	211	27	1	6	2,734	10	4.30	2.99	1.44	0.96	11.1	7.7	1.40	.287	4.77	9.58
19	Red Faber R. Faber	38	56	.404	186	87	3.78	232	32	2	12	816.2	890	343	430	33	240	19	68		3,545	11	2.56	2.64	0.97	0.36	6.5	6.8	1.38	.284	4.74	9.81
20	Greg Maddux G. Maddux	35	38	.479	99	99	4.24	311	1	0	0	589.2	637	278	304	54	88	12	0	15	2,450	7	4.75	1.34	3.53	0.82	12.7	3.6	1.23	.294	4.64	9.72
21	Dazzy Vance D. Vance	33	31	.516	130	70	3.87	390	24	3	7	621.1	642	267	307	33	179	8	26		2,653	8	5.65	2.59	2.18	0.48	14.7	6.7	1.32	.298	4.45	9.30
22	Connie Marrero C. Marrero	32	30	.516	90	74	3.49	228	42	6	2	574.1	570	223	247	43	192	12	10		2,448	10	3.57	3.01	1.19	0.67	9.3	7.8	1.33	.267	3.87	8.93
23	R.A. Dickey	31	36	.463	94	93	4.19	388	2	0	0	574.0	557	267	293	79	191	27	1	4	2,427	27	6.08	2.99	2.03	1.24	16.0	7.9	1.30	.274	4.59	8.73
24	Jerry Koosman J. Koosman	31	26	.544	92	76	4.05	287	8	3	2	493.0	515	222	247	41	147	12	6	10	2,113	13	5.24	2.68	1.95	0.75	13.6	7.0	1.34	.292	4.51	9.40
25	Tom Glavine T. Glavine	30	19	.612	79	79	4.33	257	1	1	0	461.2	488	222	236	56	163	11	0	13	1,978	3	5.01	3.18	1.58	1.09	13.0	8.2	1.41	.290	4.60	9.51