Barry Bonds played the most seasons with 68+ runs, with 21 seasons.

	NAME	SEAS	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Barry Bonds B. Bonds	21	2,219	2,972	9,805	2,923	600	77	757	1,986	2,549	106	1,533	514	141	12,554	5,948	1,434	4	90	685	165	.298	.444	.607	1.051	2653	1,138.9	.435	173	1,138
2	Rickey Henderson R. Henderson	20	2,066	2,691	9,656	2,705	446	61	274	994	1,963	82	1,481	1,308	305	11,779	4,095	781	20	58	58	157	.280	.404	.424	.828	1859	486.3	.376	135	486.9
3	Ty Cobb T. Cobb	20	2,078	2,721	10,340	3,847	658	281	110	1,782	1,160	86	600	857		11,844	5,397	1,049	258				.372	.440	.522	.962	2356	1,052.9	.452	170	944.2
4	Pete Rose P. Rose	19	1,931	2,963	12,028	3,730	684	124	154	1,130	1,322	92	971	175	130	13,555	5,124	962	48	65	153	207	.310	.381	.426	.807	1959	506.7	.363	127	406.8
5	Carl Yastrzemski C. Yastrzemski	19	1,640	2,862	10,447	3,009	565	56	404	1,613	1,639	36	1,248	168	112	12,229	4,898	1,025	12	95	169	279	.288	.383	.469	.852	1924	607.3	.379	133	452.5
6	Hank Aaron H. Aaron	19	2,002	2,842	10,820	3,378	557	90	700	2,064	1,230	28	1,226	237	69	12,198	6,215	1,347	13	107	283	286	.312	.380	.574	.955	2241	915.3	.412	159	845.6
7	Tristram Speaker T. Speaker	19	1,842	2,687	9,869	3,434	768	218	114	1,491	1,366	99	377	428		11,631	4,980	1,100	297				.348	.432	.505	.937	2228	925.2	.440	159	819.3
8	Frank Robinson F. Robinson	18	1,764	2,620	9,479	2,814	517	71	555	1,719	1,325	196	1,429	202	74	11,110	5,138	1,143	16	94	215	256	.297	.391	.542	.933	1992	780.6	.406	154	693.1
9	Derek Jeter D. Jeter	17	1,863	2,570	10,503	3,292	520	64	255	1,247	1,036	163	1,732	348	95	11,844	4,705	839	89	53	38	269	.313	.382	.448	.830	1815	367.2	.366	122	329.2
10	Alex Rodriguez A. Rodriguez	17	1,895	2,511	9,616	2,885	507	29	659	1,953	1,245	168	2,035	311	71	11,147	5,427	1,195	14	104	95	239	.300	.386	.564	.950	2059	694.2	.403	145	639.7
11	Rafael Palmeiro R. Palmeiro	17	1,575	2,615	9,809	2,843	553	37	534	1,733	1,286	83	1,273	92	37	11,302	5,072	1,124	15	109	167	215	.290	.373	.517	.890	1872	509.4	.382	131	444.1
12	Dave Winfield D. Winfield	17	1,505	2,544	9,567	2,729	473	79	417	1,631	1,076	22	1,453	200	87	10,762	4,611	969	17	80	159	275	.285	.356	.482	.838	1614	398.9	.368	131	386.7
13	Willie Mays W. Mays	17	1,863	2,566	9,434	2,907	461	127	609	1,707	1,255	36	1,283	316	91	10,818	5,449	1,197	7	86	179	214	.308	.388	.578	.966	2038	850.2	.417	160	769.6
14	Mel Ott M. Ott	17	1,762	2,453	8,781	2,713	466	67	491	1,786	1,591	61	815	79		10,532	4,786	1,024	99			33	.309	.418	.545	.963	2103	813	.436	159	786.6
15	Craig Biggio C. Biggio	16	1,646	2,415	9,378	2,666	604	45	263	1,033	990	260	1,508	350	107	10,776	4,149	912	78	70	54	121	.284	.366	.442	.808	1561	243	.356	117	235.5
16	Cal Ripken Jr. C. Ripken Jr.	16	1,444	2,520	9,793	2,710	517	43	370	1,453	1,015	54	1,098	36	34	10,975	4,423	930	4	109	103	298	.277	.344	.452	.796	1512	237.7	.350	115	193
17	Lou Brock L. Brock	16	1,522	2,400	9,618	2,833	462	137	144	850	720	46	1,655	900	290	10,470	4,001	743	46	40	121	103	.295	.345	.416	.761	1338	229	.340	112	133.9
18	Al Kaline A. Kaline	16	1,371	2,236	8,202	2,471	418	65	348	1,337	1,065	45	821	114	53	9,427	4,063	831	33	82	110	204	.301	.381	.495	.877	1549	510.2	.386	138	421.5
19	Eddie Collins E. Collins	16	1,609	2,358	8,608	2,907	365	172	42	1,144	1,286	71	397	691		10,413	3,742	579	448				.338	.428	.435	.863	1786	623.7	.413	146	563.7
20	Honus Wagner H. Wagner	16	1,530	2,271	8,570	2,891	570	225	94	1,524	813	108	577	643		9,667	4,193	889	176				.337	.402	.489	.891	1793	699.7	.423	155	631.9
21	Jake Beckley J. Beckley	16	1,484	2,065	8,306	2,587	419	225	86	1,443	565	171	377	280		9,183	3,714	730	141				.311	.368	.447	.815	1639	336.1	.383	120	276.2
22	Albert Pujols A. Pujols	15	1,621	2,327	8,747	2,724	583	16	574	1,753	1,174	95	998	106	40	10,109	5,061	1,173	1	92	294	318	.311	.395	.579	.974	1898	698.6	.406	155	688.3
23	Adrian Beltre A. Beltre	15	1,247	2,248	8,617	2,521	503	30	394	1,365	677	67	1,288	88	33	9,446	4,266	927	9	76	102	214	.293	.346	.495	.841	1391	267.9	.359	121	237.2
24	Johnny Damon J. Damon	15	1,550	2,234	8,824	2,530	483	97	222	1,047	943	46	1,144	372	98	9,921	3,873	802	45	63	35	87	.287	.356	.439	.795	1372	156.1	.348	108	103.3
25	Roberto Alomar R. Alomar	15	1,426	2,211	8,490	2,542	475	76	192	1,050	978	46	1,066	465	109	9,741	3,745	743	138	89	60	192	.299	.371	.441	.812	1426	257.1	.359	118	215.2