Houston Astros (74-71, first in the AL West) vs. Philadelphia Phillies (81-64, second in the NL East)

Philadelphia; Wednesday, 6:40 p.m. EDT

PITCHING PROBABLES: Astros: Hunter Brown (5-3, 3.31 ERA, 1.30 WHIP, 93 strikeouts); Phillies: Cristopher Sanchez (16-5, 2.58 ERA, 1.20 WHIP, 207 strikeouts)

LINE: Phillies -165, Astros +134; over/under is 8 runs

BOTTOM LINE: The Houston Astros play the Philadelphia Phillies leading the series 1-0.

Philadelphia has a 40-33 record in home games and an 81-64 record overall. The Phillies have a 25-14 record in games decided by one run.

Houston is 37-33 on the road and 74-71 overall. The Astros have gone 50-29 in games when they record eight or more hits.

The matchup Wednesday is the second time these teams match up this season.

TOP PERFORMERS: Luis Arraez leads the Phillies with a .316 batting average, and has 29 doubles, seven triples, six home runs, 28 walks and 57 RBIs. Bryce Harper is 12 for 35 with three RBIs over the last 10 games.

Yordan Alvarez has 38 home runs, 99 walks and 95 RBIs while hitting .311 for the Astros. Yainer Diaz is 13 for 36 with two doubles, three home runs and five RBIs over the past 10 games.

LAST 10 GAMES: Phillies: 6-4, .229 batting average, 2.40 ERA, outscored opponents by nine runs

Astros: 6-4, .223 batting average, 3.00 ERA, outscored opponents by five runs

INJURIES: Phillies: Caleb Kilian: 15-Day IL (oblique), Felix Reyes: 60-Day IL (wrist), Tanner Banks: 60-Day IL (forearm), Brad Keller: 60-Day IL (elbow), Johan Rojas: 60-Day IL (elbow), Adolis Garcia: 60-Day IL (lat)

Astros: Mike Burrows: 60-Day IL (elbow), Steven Okert: 15-Day IL (hamstring), Brice Matthews: 60-Day IL (knee), Carlos Correa: 60-Day IL (ankle), Brandon Walter: 60-Day IL (elbow)

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The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.