Monster Beverage (MNST) had the highest return between 2003 and 2009 by a large-cap US stock, returning 7,189.3%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2003-2009	7,189.29%
Banco Bradesco SA ADR (BBD)	2003-2009	4,426.34%
Deckers Outdoor (DECK)	2003-2009	2,972.92%
Apple (AAPL)	2003-2009	2,835.44%
Grupo Cibest (CIB)	2003-2009	2,516.26%
ArcelorMittal SA ADR (MT)	2003-2009	2,484.84%
Intuitive Surgical (ISRG)	2003-2009	2,367.03%
Booking (BKNG)	2003-2009	2,147.02%
Southern Copper (SCCO)	2003-2009	2,095.24%
Vale SA ADR (VALE)	2003-2009	1,974%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2003-2009	1,764.28%
Illumina (ILMN)	2003-2009	1,699.37%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	2003-2009	1,649.64%
Ambev SA ADR (ABEV)	2003-2009	1,623.39%
Itau Unibanco Banco (ITUB)	2003-2009	1,619.13%
Williams Companies (WMB)	2003-2009	1,498.01%
Alamos Gold (AGI)	2003-2009	1,434.52%
Akamai Technologies (AKAM)	2003-2009	1,307.78%
Chunghwa Telecom (CHT)	2003-2009	1,286.52%
Tenaris SA ADR (TS)	2003-2009	1,241.68%
Axon Enterprise (AXON)	2003-2009	1,197.78%
NetEase (NTES)	2003-2009	1,185.05%
Trip Group Ltd ADR (TCOM)	2003-2009	1,118.93%
U-Haul (UHAL)	2003-2009	1,018.46%
Elbit Systems (ESLT)	2003-2009	1,004.24%

Large-cap stocks are treated as having a market cap of $10B+.