40 best performing large cap stocks during 2000 to 2026

QXO (QXO) has had the highest return between 2000 and 2026 by a large-cap US stock, returning 5,319,900%.

ASSETYEARS% RETURN
QXO (QXO)
2000-2026
5,319,900%
NVIDIA (NVDA)
2000-2026
251,366.67%
Monster Beverage (MNST)
2000-2026
196,133.18%
Netflix (NFLX)
2000-2026
60,981.31%
Texas Pacific Land (TPL)
2000-2026
58,699.29%
Deckers Outdoor (DECK)
2000-2026
57,698.35%
Clean Harbors (CLH)
2000-2026
52,249.85%
Apple (AAPL)
2000-2026
43,379.98%
Old Dominion Freight Line (ODFL)
2000-2026
40,288.54%
Sterling Infrastructure (STRL)
2000-2026
39,995.2%
HF Sinclair (DINO)
2000-2026
35,300.35%
Broadcom (AVGO)
2000-2026
30,161.9%
Tesla (TSLA)
2000-2026
29,743.69%
Southern Copper (SCCO)
2000-2026
27,964.82%
Comfort Systems USA (FIX)
2000-2026
27,642.87%
Altria (MO)
2000-2026
26,187.6%
Intuitive Surgical (ISRG)
2000-2026
21,283.07%
NetEase (NTES)
2000-2026
21,213.73%
Tractor Supply (TSCO)
2000-2026
20,663.5%
Amphenol (APH)
2000-2026
18,822.06%
EMCOR (EME)
2000-2026
18,426.73%
Valero Energy (VLO)
2000-2026
18,216.25%
Cheniere Energy (LNG)
2000-2026
17,574.4%
XPO Logistics (XPO)
2000-2026
17,309.59%
Elbit Systems (ESLT)
2000-2026
17,131.26%
Large-cap stocks are treated as having a market cap of $10B+.