Next Technology (NXTT) had the highest return in 2022 by a US stock in the Nasdaq Composite (IXIC), returning 417,756.9%.

ASSET	YEAR	% RETURN
Next Technology (NXTT)	2022	417,756.91%
Heart Test Laboratories Inc Common Stock (HSCS)	2022	246,958.82%
SS Innovations International Inc Common Stock (SSII)	2022	126,150%
Clearmind Medicine Inc Common Shares (CMND)	2022	27,815.19%
Sunshine Biopharma (SBFM)	2022	10,747.46%
Applied Digital (APLD)	2022	9,384.54%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2022	2,400%
Electra Battery Materials (ELBM)	2022	564.27%
ENDRA Life Sciences (NDRA)	2022	473.39%
KLX Energy Services (KLXE)	2022	453.04%
United Maritime (USEA)	2022	450%
Kolibri Global Energy Inc Common stock (KGEI)	2022	391.67%
Mammoth Energy Services (TUSK)	2022	367.57%
Synergy CHC Corp Common Stock (SNYR)	2022	327.27%
Target Hospitality (TH)	2022	313.66%
Hallador Energy (HNRG)	2022	306.1%
Torm PLC Class A (TRMD)	2022	294.69%
Madrigal Pharmaceuticals (MDGL)	2022	238.09%
SurgePays (SURG)	2022	228%
TransMedics (TMDX)	2022	221.29%
Clean Energy Technologies, Inc Common Stock (CETY)	2022	203.08%
Rhythm Pharmaceuticals (RYTM)	2022	191.2%
RDE (GIFT)	2022	183%
ADMA Biologics (ADMA)	2022	177.14%
Catalyst Pharmaceuticals (CPRX)	2022	173.93%