Hirequest (HQI) had the highest return between 2000 and 2005 by a US stock, returning 43,752,250%.

ASSET	YEARS	% RETURN
Hirequest (HQI)	2000-2005	43,752,250%
InterContinental Hotels Group PLC ADR (IHG)	2000-2005	9,399,400%
Perspective Therapeutics (CATX)	2000-2005	2,416,566.67%
National Grid PLC ADR (NGG)	2000-2005	864,752.94%
Houston American Energy (HUSA)	2000-2005	815,339.5%
Cryoport (CYRX)	2000-2005	71,251.35%
ImmunoPrecise Antibodies (HYFT)	2000-2005	64,185.71%
OPTIMIZERx (OPRX)	2000-2005	13,900%
NanoViricides (NNVC)	2000-2005	12,360%
Xcel Brands (XELB)	2000-2005	9,400%
First Majestic Silver (AG)	2000-2005	9,373.78%
TherapeuticsMD (TXMD)	2000-2005	7,400.01%
Dmc Global (BOOM)	2000-2005	4,728.89%
CBAK Energy Technology (CBAT)	2000-2005	4,320%
Monster Beverage (MNST)	2000-2005	3,581.39%
Protalix Biotherapeutics (PLX)	2000-2005	3,300%
Broadwind Energy (BWEN)	2000-2005	3,260.13%
American Vanguard (AVD)	2000-2005	2,987.78%
Gulf Resources (GURE)	2000-2005	2,900%
Oramed Pharmaceuticals (ORMP)	2000-2005	2,470.84%
Flexible Solutions International (FSI)	2000-2005	2,316.43%
Clean Harbors (CLH)	2000-2005	2,263.8%
Meritage (MTH)	2000-2005	2,241.13%
Cheniere Energy (LNG)	2000-2005	2,115.58%
Companhia Siderurgica Nacional ADR (SID)	2000-2005	1,940.78%