GT Biopharma (GTBP) had the highest return between 2008 and 2012 by a US stock, returning 845,749,475%.

ASSET	YEARS	% RETURN
GT Biopharma (GTBP)	2008-2012	845,749,475%
Sequans Communications (SQNS)	2008-2012	2,819,177.11%
QXO (QXO)	2008-2012	1,791,977.78%
Castellum (CTM)	2008-2012	815,117.39%
Metalla Royalty & Streaming (MTA)	2008-2012	488,471.43%
Versus Systems Inc. (VS)	2008-2012	79,772%
PharmaCyte Biotech (PMCB)	2008-2012	27,135.71%
Aris Mining (ARMN)	2008-2012	22,581.91%
Kartoon Studios (TOON)	2008-2012	20,900%
Cementos Pacasmayo SAA ADR (CPAC)	2008-2012	17,249.33%
Pioneer Power Solutions (PPSI)	2008-2012	11,111.15%
Arena (AREN)	2008-2012	9,382.76%
INVO Fertility (IVF)	2008-2012	8,540%
Intellinetics (INLX)	2008-2012	8,066.67%
Cocrystal Pharma (COCP)	2008-2012	4,233.33%
Par Pacific (PARR)	2008-2012	1,900%
Altisource Portfolio Solutions (ASPS)	2008-2012	1,563.42%
Oxley Bridge Acquisition Limited Class A Ordinary Shares (OBA)	2008-2012	1,472.96%
Astrana Health (ASTH)	2008-2012	1,438.46%
Actinium Pharmaceuticals (ATNM)	2008-2012	1,263.64%
Virtus Investment Partners (VRTS)	2008-2012	1,243.79%
LifeMD (LFMD)	2008-2012	1,233.33%
N2OFF (NITO)	2008-2012	1,150%
Brand House Collective (TBHC)	2008-2012	1,014.72%
Lifevantage (LFVN)	2008-2012	995.04%