QXO (QXO) had the highest return between 2009 and 2012 by a large-cap US stock, returning 4,032,075%.

ASSET	YEARS	% RETURN
QXO (QXO)	2009-2012	4,032,075%
Ferguson (FERG)	2009-2012	785,661.9%
Lululemon Athletica (LULU)	2009-2012	1,817.74%
Ulta Beauty (ULTA)	2009-2012	1,095.65%
Pilgrims Pride (PPC)	2009-2012	980.65%
Domino's Pizza Inc Common Stock (DPZ)	2009-2012	896.96%
Regeneron Pharmaceuticals (REGN)	2009-2012	828.72%
Las Vegas Sands (LVS)	2009-2012	750.34%
Cheniere Energy Partners (CQP)	2009-2012	740.39%
Booking (BKNG)	2009-2012	735.32%
Expedia (EXPE)	2009-2012	727.74%
Teck Resources Ltd Class B (TECK)	2009-2012	674.9%
Baidu (BIDU)	2009-2012	659.77%
Seagate Technology (STX)	2009-2012	634.98%
Tenet Healthcare (THC)	2009-2012	587.92%
Ambev SA ADR (ABEV)	2009-2012	578.91%
Cheniere Energy (LNG)	2009-2012	561.25%
Apple (AAPL)	2009-2012	525.18%
Williams-Sonoma (WSM)	2009-2012	512.87%
Ford Motor (F)	2009-2012	473.4%
Wheaton Precious Metals (WPM)	2009-2012	473.17%
Starbucks (SBUX)	2009-2012	469.93%
Primo Brands (PRMB)	2009-2012	469.49%
Cooper Companies (COO)	2009-2012	461.81%
Smurfit WestRock (SW)	2009-2012	455.54%

Large-cap stocks are treated as having a market cap of $10B+.