Globus Medical (GMED) has had the highest return this month by a large-cap US stock, returning 38.9%.

ASSET	MONTH	% RETURN
Globus Medical (GMED)	November 2025	38.94%
Madrigal Pharmaceuticals (MDGL)	November 2025	31.25%
Penumbra (PEN)	November 2025	23.45%
Coca-Cola Consolidated (COKE)	November 2025	22.5%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	November 2025	22.01%
BeiGene (ONC)	November 2025	21.25%
Albemarle (ALB)	November 2025	20.67%
Teva Pharma Industries Ltd ADR (TEVA)	November 2025	19.37%
Eli Lilly and (LLY)	November 2025	18.08%
Revolution Medicines (RVMD)	November 2025	17.33%
Expeditors International of Washington (EXPD)	November 2025	16.84%
Akamai Technologies (AKAM)	November 2025	16.5%
Lumentum (LITE)	November 2025	16%
Huazhu (HTHT)	November 2025	15.97%
Dupont De Nemours (DD)	November 2025	14.72%
AngloGold Ashanti (AU)	November 2025	14.67%
Amgen (AMGN)	November 2025	14.5%
argenx NV ADR (ARGX)	November 2025	13.97%
Equinox Gold (EQX)	November 2025	13.59%
Expand Energy (EXE)	November 2025	13.32%
Exelixis (EXEL)	November 2025	12.97%
Ecopetrol SA ADR (EC)	November 2025	12.88%
Centrais Electricas Brasileiras (EBR)	November 2025	12.73%
On (ONON)	November 2025	12.65%
Tower Semiconductor (TSEM)	November 2025	12.16%

Large-cap stocks are treated as having a market cap of $10B+.