best performing large cap stocks in the 2000 to 2025

InterContinental Hotels Group PLC ADR (IHG) has had the highest return between 2000 and 2025 by a large-cap US stock, returning 135,649,900%.

ASSETYEARS% RETURN
InterContinental Hotels Group PLC ADR (IHG)
2000-2025
135,649,900%
Ferguson (FERG)
2000-2025
8,708,175.86%
Natwest (NWG)
2000-2025
1,637,900%
Insmed (INSM)
2000-2025
265,842.78%
NVIDIA (NVDA)
2000-2025
199,744.79%
Monster Beverage (MNST)
2000-2025
168,151.12%
QXO (QXO)
2000-2025
130,328.57%
Netflix (NFLX)
2000-2025
91,716.61%
Axon Enterprise (AXON)
2000-2025
91,305.79%
Texas Pacific Land Trust (TPL)
2000-2025
65,197.77%
Deckers Outdoor (DECK)
2000-2025
59,701.1%
Clean Harbors (CLH)
2000-2025
37,162.88%
Apple (AAPL)
2000-2025
35,198.23%
Tesla (TSLA)
2000-2025
33,576.48%
Broadcom (AVGO)
2000-2025
33,563.84%
Tractor Supply (TSCO)
2000-2025
33,150.15%
Old Dominion Freight Line (ODFL)
2000-2025
29,668.31%
Intuitive Surgical (ISRG)
2000-2025
28,612.94%
Sterling Construction (STRL)
2000-2025
27,080%
NetEase (NTES)
2000-2025
22,732.72%
Altria (MO)
2000-2025
20,061.46%
IDEXX Laboratories (IDXX)
2000-2025
18,751.87%
Southern Copper (SCCO)
2000-2025
17,457.08%
CoreSite Realty (COR)
2000-2025
16,700.24%
Comfort Systems USA (FIX)
2000-2025
16,321.15%
Large-cap stocks are treated as having a market cap of $10B+.