Applied Digital (APLD) had the highest return between 2021 and 2024 by a US stock with a market cap of $2B+, returning 3,295.6%.

ASSET	YEARS	% RETURN
Applied Digital (APLD)	2021-2024	3,295.56%
Vista Oil Gas ADR (VIST)	2021-2024	1,989.19%
Weatherford International (WFRD)	2021-2024	1,113.41%
Tecnoglass (TGLS)	2021-2024	1,086.43%
Celestica (CLS)	2021-2024	1,032.52%
Sezzle Inc Common Stock (SEZL)	2021-2024	1,029.36%
Permian Resources (PR)	2021-2024	941.34%
NVIDIA (NVDA)	2021-2024	927.3%
Super Micro Computer (SMCI)	2021-2024	858.49%
Modine Manufacturing (MOD)	2021-2024	818.62%
Sterling Construction (STRL)	2021-2024	801.77%
Grupo Financiero Galicia SA ADR (GGAL)	2021-2024	783.71%
YPF Sociedad Anonima (YPF)	2021-2024	780.12%
Fortress Transp & Infra Inv (FTAI)	2021-2024	749.94%
ADMA Biologics (ADMA)	2021-2024	749.01%
Alliance Resource Partners (ARLP)	2021-2024	739.23%
Dillards (DDS)	2021-2024	731.82%
Powell Industries (POWL)	2021-2024	721.27%
Comfort Systems USA (FIX)	2021-2024	720.24%
Banco Macro SA B ADR (BMA)	2021-2024	700.58%
BBVA Banco Frances SA ADR (BBAR)	2021-2024	698.83%
Vistra Energy (VST)	2021-2024	676.26%
Abercrombie & Fitch (ANF)	2021-2024	628.77%
Targa Resources (TRGP)	2021-2024	620.16%
Viking Therapeutics (VKTX)	2021-2024	605.96%