Booking (BKNG) had the highest return between 1990 and 2022 by a US stock, returning 660,945,133.3%.

ASSET	YEARS	% RETURN
Booking (BKNG)	1990-2022	660,945,133.33%
Johnson Controls International (JCI)	1990-2022	15,051,025%
Universal Insurance (UVE)	1990-2022	9,620,900%
Hirequest (HQI)	1990-2022	7,498,550%
GeoVax Labs (GOVX)	1990-2022	3,526,019.4%
AngloGold Ashanti (AU)	1990-2022	2,999,483.33%
BioNexus Gene Lab Corp Common stock (BGLC)	1990-2022	2,780,387.8%
KULR Technology (KULR)	1990-2022	2,399,900%
Nutex Health (NUTX)	1990-2022	1,899,900%
Zivo Bioscience (ZIVO)	1990-2022	1,363,536.36%
QXO (QXO)	1990-2022	1,102,329.41%
Sequans Communications (SQNS)	1990-2022	999,900%
MDxHealth SA ADR (MDXH)	1990-2022	734,344.44%
Future Fintech (FTFT)	1990-2022	591,900%
Connexa Sports Technologies (YYAI)	1990-2022	467,900%
Jack Henry & Associates (JKHY)	1990-2022	440,442.3%
Live Ventures (LIVE)	1990-2022	287,055.96%
Monster Beverage (MNST)	1990-2022	268,497.88%
Heart Test Laboratories Inc Common Stock (HSCS)	1990-2022	246,958.82%
AquaBounty Technologies (AQB)	1990-2022	212,122.22%
Immatics (IMTX)	1990-2022	174,100%
UnitedHealth (UNH)	1990-2022	170,161.57%
Iqstel (IQST)	1990-2022	146,895.96%
Eastside Distilling (BLNE)	1990-2022	137,437.54%
Integra Resources (ITRG)	1990-2022	126,500%