FirstEnergy (FE) had the highest return between 1997 and 2022 by a US stock, returning 37,743,500%.

ASSET	YEARS	% RETURN
FirstEnergy (FE)	1997-2022	37,743,500%
JJill (JILL)	1997-2022	4,084,933.33%
BioNexus Gene Lab Corp Common stock (BGLC)	1997-2022	2,780,387.8%
Graphex (GRFX)	1997-2022	799,900%
Monster Beverage (MNST)	1997-2022	373,172.06%
Ferguson (FERG)	1997-2022	272,487.92%
Immatics (IMTX)	1997-2022	174,100%
Know Labs (KNW)	1997-2022	162,749.87%
AppTech Payments Corp Warrant (APCXW)	1997-2022	140,200%
Eastside Distilling (BLNE)	1997-2022	137,437.54%
Suburban Propane Partners (SPH)	1997-2022	119,200%
Perspective Therapeutics (CATX)	1997-2022	83,233.33%
Texas Pacific Land Trust (TPL)	1997-2022	82,906.03%
Apple (AAPL)	1997-2022	80,728.63%
Amazon (AMZN)	1997-2022	68,808.94%
ReShape Lifesciences (RSLS)	1997-2022	65,053.33%
NVIDIA (NVDA)	1997-2022	36,316.71%
NVR (NVR)	1997-2022	35,381.38%
Old Dominion Freight Line (ODFL)	1997-2022	32,259.71%
Cognizant Technology Solutions Corp Class A (CTSH)	1997-2022	29,378.93%
Faraday Future Intelligent Electric (FFIE)	1997-2022	28,779.58%
Axon Enterprise (AXON)	1997-2022	28,346.77%
Riley Exploration Permian (REPX)	1997-2022	27,562.33%
Netflix (NFLX)	1997-2022	25,399.83%
Smith & Wesson Brands (SWBI)	1997-2022	23,751.65%