QVC (QVCGA) had the highest return between 2000 and 2008 by a US stock, returning 1,617,809.3%.

ASSET	YEARS	% RETURN
QVC (QVCGA)	2000-2008	1,617,809.26%
Global Ship Lease (GSL)	2000-2008	1,384,370%
Houston American Energy (HUSA)	2000-2008	853,743.24%
National Grid PLC ADR (NGG)	2000-2008	594,562.96%
Know Labs (KNW)	2000-2008	534,224.43%
Ring Energy (REI)	2000-2008	146,566.67%
Ocean Power Technologies (OPTT)	2000-2008	74,233.33%
Perspective Therapeutics (CATX)	2000-2008	66,566.67%
India Globalization Capital (IGC)	2000-2008	17,829.76%
Future Fintech (FTFT)	2000-2008	12,400%
Northern Oil & Gas (NOG)	2000-2008	9,354.68%
MAG Silver (MAG)	2000-2008	8,478.52%
First Majestic Silver (AG)	2000-2008	7,846.22%
TherapeuticsMD (TXMD)	2000-2008	7,439.95%
Monster Beverage (MNST)	2000-2008	6,165.02%
Gulf Resources (GURE)	2000-2008	5,900%
Broadwind Energy (BWEN)	2000-2008	5,300.22%
Clean Harbors (CLH)	2000-2008	5,105.12%
Companhia Siderurgica Nacional ADR (SID)	2000-2008	4,336.27%
Amedisys (AMED)	2000-2008	3,908.92%
Oramed Pharmaceuticals (ORMP)	2000-2008	3,134.28%
Dmc Global (BOOM)	2000-2008	3,047.74%
Deckers Outdoor (DECK)	2000-2008	2,943.35%
BRF SA ADR (BRFS)	2000-2008	2,860.41%
Team (TISI)	2000-2008	2,854.67%