India Globalization Capital (IGC) had the highest return between 2000 and 2008 by a US stock, returning 1,616,566.7%.

ASSET	YEARS	% RETURN
India Globalization Capital (IGC)	2000-2008	1,616,566.67%
Cemtrex (CETX)	2000-2008	1,489,046.69%
Hirequest (HQI)	2000-2008	929,050%
Taoping (TAOP)	2000-2008	863,957.6%
Houston American Energy (HUSA)	2000-2008	853,743.24%
Northern Oil & Gas (NOG)	2000-2008	838,607.69%
NextTrip (NTRP)	2000-2008	159,900%
Ring Energy (REI)	2000-2008	146,566.67%
Inseego (INSG)	2000-2008	77,233.33%
Ocean Power Technologies (OPTT)	2000-2008	74,233.33%
Perspective Therapeutics (CATX)	2000-2008	66,566.67%
ProMIS Neurosciences (PMN)	2000-2008	64,385.98%
Alto Ingredients (ALTO)	2000-2008	32,230.3%
Frontline (FRO)	2000-2008	19,305.16%
PharmaCyte Biotech (PMCB)	2000-2008	12,988.89%
NanoViricides (NNVC)	2000-2008	11,240%
TherapeuticsMD (TXMD)	2000-2008	7,439.95%
Monster Beverage (MNST)	2000-2008	6,165.02%
Broadwind Energy (BWEN)	2000-2008	5,300.22%
Clean Harbors (CLH)	2000-2008	5,105.12%
Companhia Siderurgica Nacional ADR (SID)	2000-2008	4,336.27%
MiMedx (MDXG)	2000-2008	4,300%
ImmunoPrecise Antibodies (HYFT)	2000-2008	4,185.71%
Oramed Pharmaceuticals (ORMP)	2000-2008	3,134.28%
Dmc Global (BOOM)	2000-2008	3,047.74%