National CineMedia (NCMI) had the highest return in April 2023 by a US stock with a market cap of $300M to $10B, returning 122.6%.

ASSET	MONTH	% RETURN
National CineMedia (NCMI)	April 2023	122.64%
Eyepoint Pharmaceuticals (EYPT)	April 2023	114.33%
Pulse Biosciences (PLSE)	April 2023	87.76%
Terawulf (WULF)	April 2023	87.37%
Mereo BioPharma Group PLC ADR (MREO)	April 2023	84.51%
Trevi Therapeutics (TRVI)	April 2023	83.96%
TG Therapeutics (TGTX)	April 2023	65.42%
Sana Biotechnology (SANA)	April 2023	64.29%
Soleno Therapeutics (SLNO)	April 2023	60.48%
Akebia Ther (AKBA)	April 2023	58.22%
Disc Medicine (IRON)	April 2023	54.31%
Tourmaline Bio (TRML)	April 2023	54.01%
Phathom Pharmaceuticals (PHAT)	April 2023	52.2%
Immunitybio (IBRX)	April 2023	52.17%
Collective Mining (CNL)	April 2023	51.67%
American Coastal Insurance (ACIC)	April 2023	49.64%
Oculis Holding AG Ordinary shares (OCS)	April 2023	48.6%
Legend Biotech (LEGN)	April 2023	45.76%
CleanSpark (CLSK)	April 2023	44.81%
Brookdale Senior Living (BKD)	April 2023	43.96%
Bright Minds Biosciences (DRUG)	April 2023	42.95%
Applied Digital (APLD)	April 2023	40.97%
Arrowhead Pharmaceuticals (ARWR)	April 2023	39.52%
Arcellx (ACLX)	April 2023	39.3%
Annexon (ANNX)	April 2023	38.51%