best performing stocks in nasdaq last week market cap bigger than 1 billion

Uniqure (QURE) had the highest return last week by a US stock in the Nasdaq Composite (IXIC), returning 290.7%.

ASSET WEEK % RETURN
Uniqure (QURE)
9/22/2025 - 9/28/2025
290.72%
New Era Helium Inc Common Stock (NEHC)
9/22/2025 - 9/28/2025
180.06%
Applied Therapeutics (APLT)
9/22/2025 - 9/28/2025
175.56%
PepGen (PEPG)
9/22/2025 - 9/28/2025
172.58%
Datavault AI (DVLT)
9/22/2025 - 9/28/2025
136.96%
LakeShore Biopharma (LSB)
9/22/2025 - 9/28/2025
128.57%
Soluna (SLNH)
9/22/2025 - 9/28/2025
127.27%
SHF (SHFS)
9/22/2025 - 9/28/2025
123.62%
RedCloud Holdings plc Ordinary Shares (RCT)
9/22/2025 - 9/28/2025
105.68%
DarioHealth (DRIO)
9/22/2025 - 9/28/2025
100.76%
Clearpoint Neuro (CLPT)
9/22/2025 - 9/28/2025
93.1%
Chardan NexTech Acquisition 2 (DFLI)
9/22/2025 - 9/28/2025
85.82%
Mercurity Fintech Holding Inc ADR (MFH)
9/22/2025 - 9/28/2025
81.9%
Aqua Metals (AQMS)
9/22/2025 - 9/28/2025
79.8%
American Rebel (AREB)
9/22/2025 - 9/28/2025
69.67%
Medirom Healthcare Technologies (MRM)
9/22/2025 - 9/28/2025
68%
Better Home & Finance (BETR)
9/22/2025 - 9/28/2025
59.51%
Kodiak Sciences (KOD)
9/22/2025 - 9/28/2025
58%
Skyline Builders Group Holding Limited Class A Ordinary Shares (SKBL)
9/22/2025 - 9/28/2025
55.46%
Palisade Bio (PALI)
9/22/2025 - 9/28/2025
54.86%
Galecto  (GLTO)
9/22/2025 - 9/28/2025
53.66%
Alx Oncology Holdings  (ALXO)
9/22/2025 - 9/28/2025
53.28%
STRATA Skin Sciences (SSKN)
9/22/2025 - 9/28/2025
52.9%
Prelude Therapeutics  (PRLD)
9/22/2025 - 9/28/2025
51.52%
Sunrise New Energy (EPOW)
9/22/2025 - 9/28/2025
48.19%