best performing stocks in the large cap 2000 to 2025

InterContinental Hotels Group PLC ADR (IHG) has had the highest return between 2000 and 2025 by a large-cap US stock, returning 123,259,900%.

ASSETYEARS% RETURN
InterContinental Hotels Group PLC ADR (IHG)
2000-2025
123,259,900%
Ferguson (FERG)
2000-2025
8,474,727.59%
National Grid PLC ADR (NGG)
2000-2025
4,473,429.41%
Natwest (NWG)
2000-2025
1,548,900%
Insmed (INSM)
2000-2025
252,461.77%
NVIDIA (NVDA)
2000-2025
224,833.48%
Monster Beverage (MNST)
2000-2025
149,160.09%
QXO (QXO)
2000-2025
126,757.14%
Axon Enterprise (AXON)
2000-2025
126,572.38%
Netflix (NFLX)
2000-2025
94,071.57%
Texas Pacific Land Trust (TPL)
2000-2025
70,161.07%
Deckers Outdoor (DECK)
2000-2025
55,380.11%
Clean Harbors (CLH)
2000-2025
35,231.47%
Tesla (TSLA)
2000-2025
34,643.82%
Apple (AAPL)
2000-2025
34,381.01%
Tractor Supply (TSCO)
2000-2025
32,719.89%
Broadcom (AVGO)
2000-2025
31,777.22%
Sterling Construction (STRL)
2000-2025
30,222.4%
Old Dominion Freight Line (ODFL)
2000-2025
30,184.64%
Intuitive Surgical (ISRG)
2000-2025
26,402.33%
NetEase (NTES)
2000-2025
22,975.01%
Altria (MO)
2000-2025
19,532.3%
Southern Copper (SCCO)
2000-2025
18,136.37%
Comfort Systems USA (FIX)
2000-2025
16,181.59%
IDEXX Laboratories (IDXX)
2000-2025
15,574.31%
Large-cap stocks are treated as having a market cap of $10B+.