National Grid PLC ADR (NGG) had the highest return between 2004 and 2005 by a large-cap US stock, returning 864,752.9%.

ASSET	YEARS	% RETURN
National Grid PLC ADR (NGG)	2004-2005	864,752.94%
Monster Beverage (MNST)	2004-2005	1,772.18%
Intuitive Surgical (ISRG)	2004-2005	585.79%
Apple (AAPL)	2004-2005	567.35%
Cheniere Energy (LNG)	2004-2005	536.79%
Bancolombia SA ADR (CIB)	2004-2005	501.39%
CME (CME)	2004-2005	414.46%
Banco Bradesco SA ADR (BBD)	2004-2005	400.27%
WESCO International (WCC)	2004-2005	381.73%
Valero Energy (VLO)	2004-2005	345.38%
Hologic (HOLX)	2004-2005	333.62%
Alphabet Inc Class A (GOOGL)	2004-2005	314.82%
Canadian Natural Resources (CNQ)	2004-2005	297.71%
Nasdaq (NDAQ)	2004-2005	290.89%
Tenaris SA ADR (TS)	2004-2005	269.82%
Autodesk (ADSK)	2004-2005	253.9%
Woori Financial (WF)	2004-2005	239.85%
America Movil SAB de CV ADR (AMX)	2004-2005	230.46%
Cameco (CCJ)	2004-2005	228.2%
Clean Harbors (CLH)	2004-2005	224.07%
Suzano Papel e Celulose SA ADR (SUZ)	2004-2005	224.05%
EOG Resources (EOG)	2004-2005	220.96%
Teck Resources Ltd Class B (TECK)	2004-2005	220.26%
Vale SA ADR (VALE)	2004-2005	216.49%
Orix Corp Ads (IX)	2004-2005	212.8%

Large-cap stocks are treated as having a market cap of $10B+.