InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2003 and 2007 by a US stock with a market cap of $1B+, returning 11,160,200%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	2003-2007	11,160,200%
Natwest (NWG)	2003-2007	9,034,940%
Northern Oil & Gas (NOG)	2003-2007	2,241,830.77%
National Grid PLC ADR (NGG)	2003-2007	1,704,843.75%
Americas Silver (USAS)	2003-2007	11,734.48%
Monster Beverage (MNST)	2003-2007	8,307.29%
BlackBerry (BB)	2003-2007	5,066.29%
Cheniere Energy (LNG)	2003-2007	4,921.47%
Deckers Outdoor (DECK)	2003-2007	4,584.28%
Companhia Siderurgica Nacional ADR (SID)	2003-2007	4,192.4%
DXP Enterprises (DXPE)	2003-2007	4,182.57%
Axon Enterprise (AXON)	2003-2007	4,163.7%
Denison Mines (DNN)	2003-2007	4,093.52%
ArcelorMittal SA ADR (MT)	2003-2007	3,840.47%
Frontline (FRO)	2003-2007	2,829.59%
Apple (AAPL)	2003-2007	2,658.07%
Intuitive Surgical (ISRG)	2003-2007	2,526.15%
Williams Companies (WMB)	2003-2007	2,493.2%
Gerdau SA ADR (GGB)	2003-2007	2,394.18%
Banco Bradesco SA ADR (BBD)	2003-2007	2,377.73%
Vale SA ADR (VALE)	2003-2007	2,113.18%
Hub (HUBG)	2003-2007	2,105.8%
Southern Copper (SCCO)	2003-2007	2,025.47%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2003-2007	1,997.51%
Cleveland-Cliffs (CLF)	2003-2007	1,966.26%